Hellp syndrome, reversible posterior leukoencephalopathy syndrome and eclampsia

Grzesiuk, Anderson Kuntz; Melo, Renato de Souza; Carvalho, Ademar Rodrigues

doi:10.1590/s0004-282x2009000600028

Cited by 4 publications

(2 citation statements)

References 11 publications

(13 reference statements)

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“…Consequently, this autoregulation affords better protection against damaging hypertension to the anterior than the posterior circulation. However, the protective sympathetic mechanism of the anterior circulation also may be overcome in severe cases and the brain stem, basal ganglia, frontal and temporal lobes, and cerebellum may also be involved [7], [8], [10], [13]- [16], [18], [19], [21]- [23]. In our case, the involvement of the left occipital lobe, both hemispheres of parietal and frontal lobes bilaterally, and the cerebellum bilaterally indicates a severe disturbance in cerebral autoregulation.…”

Section: Discussionmentioning

confidence: 81%

Postpartum HELLP syndrome associated with posterior reversible encephalopathy syndrome: a case report and literature review

Incognito¹,

Genovese²,

Incognito³

et al. 2023

Ital J Gynaecol Obstet

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Background: Hemolysis, elevated liver enzymes, low platelets (HELLP) syndrome is a lifethreatening pregnancy complication. Various mechanism may lead to diffuse endothelial damage which causes multi-organ dysfunctions, with possible brain involvement. We report a rare case of postpartum HELLP syndrome associated with posterior reversible encephalopathy syndrome (PRES) and conducted a literature review from the PubMed, Embase, and Cochrane databases to summarize the clinical, laboratory and radiological characteristics. We found only 10 papers describing this association occurring during pregnancy and 7 articles in the post-partum.Case presentation: Our patient developed brief hypertensive peaks followed by two episodes of generalized tonic-clonic convulsions during postpartum. Brain magnetic resonance imaging allowed the diagnosis of PRES and an association with HELLP syndrome was established after blood exams. After medical therapy, the follow-up was marked by full recovery. Conclusion:Patients with PRES do not always show typical manifestations and MRI is crucial for its diagnosis. Cases of postpartum PRES with involvement of anterior brain regions after HELLP syndrome are rare but must be considered and they should be kept in mind as a differential diagnosis in women presenting with seizures, headache and altered mentation. Clinicians should be aware of this neurological syndrome because prompt diagnosis and treatment may result in complete resolution.

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Section: Discussionmentioning

confidence: 81%

Postpartum HELLP syndrome associated with posterior reversible encephalopathy syndrome: a case report and literature review

Incognito¹,

Genovese²,

Incognito³

et al. 2023

Ital J Gynaecol Obstet

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“…This syndrome is characterized by microangiopathic hemolytic anemia, increased circulating liver enzymes and thrombocytopenia. It is an important complication regarding the third semester, and it usually happens in women diagnosed with preeclampsia, although it was also described in women without this diagnosis, as originally described by Weinstein in 1982. (GRZESIUK et al, 2009.…”

Section: Discussionmentioning

confidence: 99%

Nível Cognitivo De Pacientes Admitidos Em Asilos E Sua Correlação Ocupacional

Santos¹,

Macedo²,

Rebello³

et al. 2020

Frente Diagnóstica E Terapêutica Na Neurologia

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Todo o conteúdo deste livro está licenciado sob uma Licença de Atribuição Creative Commons. Atribuição 4.0 Internacional (CC BY 4.0). O conteúdo dos artigos e seus dados em sua forma, correção e confiabilidade são de responsabilidade exclusiva dos autores. Permitido o download da obra e o compartilhamento desde que sejam atribuídos créditos aos autores, mas sem a possibilidade de alterá-la de nenhuma forma ou utilizá-la para fins comerciais.

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Features of magnetic resonance imaging brain in eclampsia: clinicoradiologic correlation

Mubarak¹,

Idris²,

Hadi³

2012

RMI

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Objective: Eclampsia is a gestational hypertensive condition that typically occurs after 20 weeks of pregnancy and is characterized by hypertension, peripheral edema, proteinuria, and seizures. Magnetic resonance imaging (MRI) plays a vital role in the diagnosis and management of these patients, so it is essential to describe features of the brain MRI in these cases. Methods: MRI was performed on eleven consecutive patients with eclampsia. All patients underwent follow-up neurologic examinations until all symptoms resolved. Nine of those eleven patients underwent follow-up MRI. The clinical signs and symptoms were correlated with findings on initial and follow-up MRI. Results: MRI typically demonstrated bilateral hyperintense lesions on T2-weighted images and hypointense lesions on T1-weighted images without diffusion restriction. MRI abnormalities are most commonly located in the distribution of the posterior cerebral circulation mainly in occipital and parietal lobes, and are associated with visual disturbances and dizziness. Almost all lesions seen at MRI in patients with eclampsia were reversible in our series of patients. Conclusion: Involvement of the parietal and occipital lobes is common in patients with eclampsia, and the signal abnormalities on MRI are reversible if recognized and treated early.

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Hellp syndrome, reversible posterior leukoencephalopathy syndrome and eclampsia

Cited by 4 publications

References 11 publications

Postpartum HELLP syndrome associated with posterior reversible encephalopathy syndrome: a case report and literature review

Postpartum HELLP syndrome associated with posterior reversible encephalopathy syndrome: a case report and literature review

Nível Cognitivo De Pacientes Admitidos Em Asilos E Sua Correlação Ocupacional

Features of magnetic resonance imaging brain in eclampsia: clinicoradiologic correlation

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