Treatment of cerebral cysticercosis with albendazole in elevated dosages

Rocha, Marco Antônio; Santos, Juliana Machado Santiago dos; Gomes, Elisa Conci de Souza; Rocha, Cristiane Franklin; Carvalho, Gervásio Teles Cardoso de; Costa, Bruno Silva

doi:10.1590/s0004-282x2008000100032

Cited by 8 publications

(7 citation statements)

References 6 publications

(16 reference statements)

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“…Other non-responsive NC cases have been previously published (Table 1, [9-12]) but including patients that differ in the clinical picture, the parasite localization and cysticidal doses used. Even though the causes of the parasite's persistence, despite the ABZ treatment, are still unknown, multiple host and parasite factors may be involved.…”

Section: Resultsmentioning

confidence: 99%

Subarachnoidal Neurocysticercosis non-responsive to cysticidal drugs: a case series

et al. 2010

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BackgroundNeurocysticercosis (NC) is one of the most frequent parasitic diseases of the central nervous system. Cysticidal drugs, albendazole and praziquantel, are generally effective when parasites localize in the parenchyma. In contrast, parasites lodged in the subarachnoid basal cisterns are less responsive to treatment.Case PresentationThe clinical and radiological pictures of six Mexican patients non-respondent to cysticidal treatment are presented.ConclusionsThe possible factors involved in the cysticidal non-response are discussed and hints are provided of potentially useful changes to therapeutic protocols.

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Section: Resultsmentioning

confidence: 99%

Subarachnoidal Neurocysticercosis non-responsive to cysticidal drugs: a case series

et al. 2010

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“…No caso relatado, tendo-se em vista a magnitude da lesão intracraniana e a sintomatologia de compressão do parênquima cerebral pelo cisto gigante, com instabilidade importante do quadro neurológico, a intervenção cirúrgica é a conduta terapêutica mais recomendada 13 . A NCC é uma doença relativamente prevalente no nosso meio.…”

Section: Imagem Em Medicinaunclassified

“…Colli ainda cita que o melhor tratamento para a forma tumoral da NCC é a exérese cirúrgica por acesso direto 12 . No caso relatado optou-se por tratamento cirúrgico da lesão 13 . Essa cirurgia visa a exérese dos cistos por abordagem direta, ou pelo menos à sua ressecção parcial, e é realizada com relativa facilidade quando o cisto gigante está …”

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Neurocisticercose gigante: diagnóstico e tratamento

Brandão¹,

Nunes²,

Filho³

et al. 2010

Rev. Assoc. Med. Bras.

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“…Most patients respond to praziquantel, if cystic lesions are located in the parenchymal tissue, and albendazole when parasites are located in the ventricular system and subarachnoid space, including patients with an associated HIV infection [2]. A well-designed clinical trial about treatment response in subarachnoid neurocysticercosis (SNCC) has not been published; however, some authors have reported the effectiveness of these drugs in SNCC [3][4][5], while others have found that parasites remain alive at the subarachnoid space even after high dose of albendazole/praziquantel/prednisone was administered [6][7][8][9][10].…”

Section: Introductionmentioning

confidence: 99%

Subarachnoid Cysticercosis and Ischaemic Stroke in Epileptic Patients

Foyaca-Sibat¹,

Valdés²

2018

Seizures

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Whether subarachnoid neurocysticercosis (SNCC) induces ischaemic stroke (IS) in epileptic patients is not yet confirmed because only short-case series and anecdotal case reports have been published, and no observational studies exist in the literature to date. Our main goals are: to estimate the prevalence of ischaemic stroke in epileptic patients presenting with SNCC and stroke frequency among HIV-positive patients in three subgroups; to determine if the odds of ischaemic stroke are elevated in SNCCepileptic patients compared to epileptic patients with intraparenchymal NCC (INCC); to determine whether the risk for stroke is elevated in HIV-seropositive patients presenting with SNCC or INCC and epilepsy; and to evaluate if and when the potential interaction varies by location of NCC in the brain (intraparenchymal or subarachnoid). Eligible epileptic patients' seropositive status was recorded, and cross-associations for the independent variables (NCC status and HIV status) and outcome variables (ischaemic stroke event) were performed. Compared to the reference group, the odds of IS in PLWNCC were 2.0 and 2.6 times greater in patients with SNCC and INCC, respectively. The frequency of IS was greater in HIV-positive patients in all three groups, but the risk was especially pronounced when seropositive epileptic patients were both NCC groups when compared with the reference group. Subarachnoid NCC increased the risk of IS three time more.

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Treatment of cerebral cysticercosis with albendazole in elevated dosages

Cited by 8 publications

References 6 publications

Subarachnoidal Neurocysticercosis non-responsive to cysticidal drugs: a case series

Subarachnoidal Neurocysticercosis non-responsive to cysticidal drugs: a case series

Neurocisticercose gigante: diagnóstico e tratamento

Subarachnoid Cysticercosis and Ischaemic Stroke in Epileptic Patients

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