Padronização da Multiple Sclerosis Functional Composite Measure (MSFC) na população brasileira

The clinical manifestations of multiple sclerosis (MS) are variable among patients, and the course of disease is not linear. Different symptoms are presented, with gradual accumulation of disability. These variations are difficult to quantify in clinical practice, and several studies have attempted to create instruments capable of measuring these disabilities. The Six Step Spot Test (SSST) was developed for quantitative evaluation of the lower limbs (LL) over time. Performance in this test reflects the complexity of sensory-motor function, including LL strength, spasticity, coordination and balance, going beyond vision and cognition. The aim of the present study was to validate the SSST in a population of MS patients in Brazil. This prospective study included 75 patients with MS, with EDSS 0 to 6.5 in the study group. Ninety-one healthy subjects were randomly selected for the control group. The results showed that the groups were similar, and that the SSST is a reliable and reproducible test. According to the statistical analysis on the data in this study, the SSST is a valid, reliable and reproducible tool for use in the Brazilian MS patient population. Key words: gait, multiple sclerosis, disability evaluation, validation studies, reproducibility of results.Validação do teste de marcha "six step spot test" em pacientes com esclerose múltipla no brasil resumo As manifestações clínicas da esclerose múltipla (EM) são variáveis e o curso da doença não é linear, caracterizado por sintomas, acúmulo progressivo de incapacidades. Estas variações são difíceis de quantificar na prática clínica, motivo pelo qual surgiram diversos estudos para criação de instrumentos capazes de mensurar essas incapacidades. O Six Step Spot Test (SSST) foi desenvolvido para avaliar função dos membros inferiores (MMII) de forma quantitativa, mensurado no domínio tempo, avaliando a complexa função sensório-motora, como força em MMII, espasticidade, coordenação e equilíbrio, além da visão e cognição. Este estudo teve como objetivo validar o SSST para pacientes com EM no Brasil. Estudo prospectivo do qual participaram 75 pacientes com EM e EDSS de 0 a 6,5 no grupo de estudo e 91 indivíduos saudáveis no controle que foram selecionados aleatoriamente. Segundo os dados estatísticos deste estudo, o SSST é válido, confiável e reprodutível para pacientes com EM no Brasil. Palavras-chave: marcha, esclerose múltipla, avaliação da deficiência, estudos de validação, reprodutibilidade dos testes.

Section: Reliability Testsupporting

confidence: 84%

Section: Reliability Testmentioning

confidence: 99%

Validation of the "Six Step Spot Test" for gait among patients with multiple sclerosis in Brazil

Pavan¹,

Tilbery²,

Lianza³

et al. 2010

“…The patient was instructed to wear comfortable shoes, and to use an assistive device if necessary. A timer (stopwatch) was required to measure the time needed to cover the 25-foot distance in seconds 19,20 . The subject was instructed to walk from the starting point as safely and as quickly as possible.…”

Section: Methodsmentioning

confidence: 99%

Cross-cultural adaptation and validation of the 12-item Multiple Sclerosis Walking Scale (MSWS-12) for the Brazilian population

Marangoni¹,

Pavan²,

Tilbery³

2012

Gait impairment is reported by 85% of patients with multiple sclerosis (MS) as main complaint. In 2003, Hobart et al. developed a scale for walking known as The 12-item Multiple Sclerosis Walking Scale (MSWS-12), which combines the perspectives of patients with psychometric methods. OBJECTIVE: This study aimed to cross-culturally adapt and validate the MSWS-12 for the Brazilian population with MS. METHODS: This study included 116 individuals diagnosed with MS, in accordance with McDonald's criteria. The steps of the adaptation process included translation, back-translation, review by an expert committee and pretesting. A test and retest of MSWS-12/BR was made for validation, with comparison with another scale (MSIS-29/BR) and another test (T25FW). RESULTS: The Brazilian version of MSWS-12/BR was shown to be similar to the original. The results indicate that MSWS-12/BR is a reliable and reproducible scale. CONCLUSIONS: MSWS-12/BR has been adapted and validated, and it is a reliable tool for the Brazilian population.

“…In the last few years, many MS-specific scales have being translated, validated and standardized into the Portuguese language. Two independent groups developed the Brazilian version of the multiple sclerosis functional composite measure (MSFC), an instrument that assesses motor functions of legs and arms/ hands besides cognitive function 6,7 . The MSFC is not suitable to patients with advanced disease who are unable to walk, to manipulate fine objects with their hands or to process mental arithmetics 5 .…”

Section: Validação Da Versão Brasileira Da Escala De Incapacidade Neumentioning

confidence: 99%

Validation of the brazilian version of Guy's neurological disability scale

Araújo

Simão

Ybarra

et al. 2007

-The Guy's neurological disability scale (GNDS) has recently been introduced as a new measure of disability in multiple sclerosis. It is patient-oriented, multidimensional, and not biased towards any particular disability. The purpose of the present study was to validate the Brazilian version of the GNDS. The adaptation of the scale was based on the translation/back-translation methodology. Sixty-two patients with clinically definite multiple sclerosis (CDMS) according to Poser's criteria were recruited for this study. GNDS was administered individually to each subject. The EDSS and the ambulation index (AI) scores were assigned by a neurologist. The intraclass correlation coefficient and the Cronbach's a values of the Brazilian version of GNDS (0.94 and 0.83, respectively) were comparable to the original one (0.98 and 0.79, respectively). Furthermore, the factor analysis of the Brazilian version of GNDS suggested, as the original article, a four-factor solution which accounted for 68.8% of the total variance. The Brazilian version of GNDS was found to be clinically relevant as it correlated significantly with the EDSS and AI. In conclusion, the Brazilian version of GNDS can be considered an important tool to evaluate the disability in MS patients, with clinical usefulness and psychometrics soundness.KEY WORDS: multiple sclerosis, Guy's neurological disability scale, expanded disability status scale (EDSS), disability. Validação da versão brasileira da escala de incapacidade neurológica de GuyRESUMO -A Guy's neurological disability scale (GNDS) é uma escala de incapacidade criada recentemente, orientada para o paciente, multidimensional, e que não privilegia nenhum tipo específico de incapacidade. O objetivo deste estudo é validar a GNDS para a língua portuguesa. A adaptação da escala foi feita através do método de tradução e re-tradução. Sessenta e dois pacientes com esclerose múltipla (EM) clinicamente definida de acordo com os critérios de Poser participaram deste estudo. A GNDS foi aplicada individualmente em cada paciente. O EDSS e o índice ambulatorial (IA) foram determinados por neurologista. A correlação intra-classe e o valor de Cronbach's a da versão brasileira da GNDS (0.94 e 0.83, respectivamente) foram comparáveis aos do artigo original (0.98 e 0.79, respectivamente). Como no artigo original, a análi-se fatorial da versão brasileira da GNDS sugeriu uma solução de quatro fatores que explicaria 68.8% da variação total. A versão brasileira da GNDS mostrou-se clinicamente relevante uma vez que se correlacionou com o EDSS e o IA. Em conclusão, a versão brasileira da GNDS pode ser considerada como um importante instrumento de avaliação incapacidade na EM com significado clínico e relevância psicométrica. PALAVRAS-CHAVE: esclerose múltipla, escala de incapacidade neurológica de Guy, EDSS, incapacidade.