Cirurgia para epilepsia na infância: avaliação neuropsicológica e de qualidade de vida

Guimarães, Catarina Abraão; Souza, Elisabete Abib Pedroso de; Montenegro, Maria Augusta; Cendes, Fernando; Guerreiro, Marilisa M.

doi:10.1590/s0004-282x2003000500016

Cited by 9 publications

(11 citation statements)

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“…With respect to the overall outcome of QOL, the survey found that almost all patients showed significant improvement, which concurs with other results 3,14,[16][17][18][22][23][24][25][26][27] . Despite the excellent control of seizures, only one of our patients had a decrease in the overall QOL score (subject 13), mainly due to social, school and behavioral factors.…”

Section: Discussionsupporting

confidence: 88%

“…All subjects indicated a high level of perception of seizure control (attributed to a maximum value when questioned about it). Other studies have also found a high degree of seizure control 14,16,19,26 and positive correlations between the control and the degree of patient satisfaction 14,16,17,[23][24][25][26][27][28] . However, our findings were higher than those of the literature and, again, this is probably due to the strict inclusion criteria in our study and the fact that we have focused on surgery for TLE only, excluding other more serious etiologies.…”

Section: Discussionmentioning

confidence: 83%

“…The variables with significant influence on the improvement of QOL after surgery for TLE were: general health 18,27,29 , the negative effects of AEDs 22,26 and parental behavior in relation to their children 14,22,25 . Mikati et al 18 found that the severity of symptoms, side effects of medication, general health and well-being improved after surgery, leading to consequent improvement of QOL.…”

Section: Discussionmentioning

confidence: 99%

“…The QOL questionnaire given to the epilepsy surgery patient consists of seven parts concerning personal identification and information about the disease (including the perception item of seizure control); general health issues (physical, emotional, social, educational and leisure); physical issues (possible limitations to physical activities practiced by the patient); side effects of medication; psychological aspects (data on behavior, emotional and cognitive abilities of the child: concentration, memory, language and motor skills); social aspects (social interaction, leisure and schooling); and environmental influences (parental behavior towards the child) 14 .…”

Section: Methodsmentioning

confidence: 99%

“…In refractory cases, epilepsy surgery may control the seizures 1,3,13 . The aim of the surgery is not only to control the seizures, but also to improve the QOL of the patients 14 . The comparison between presurgical evaluation with postsurgical assessment allows us to analyze how much the patient improved and in which aspects of QOL the performance is better.…”

mentioning

confidence: 99%

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Quality of life and epilepsy surgery in childhood and adolescence

Gagliardi

Guimarães

Souza

et al. 2011

Arq. Neuro-Psiquiatr.

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Epilepsy can affect the quality of life (QOL) of patients. The temporal lobe epilepsy (TLE) is often refractory to medication, which has an adverse impact on QOL. The surgery can be a form to control the seizures and to improve the QOL of the patients. Objective: The aim of this study was to verify the QOL of children and adolescents with TLE who underwent surgery for epilepsy, comparing QOL before and after surgery and investigating which parameters showed improvement. Method: We used semi-structured questionnaire in the pre-and post-surgery in 13 patients. The data were analyzed using the Wilcoxon test. Results: The analysis showed that there was general improvement in the QOL postoperatively. There was improvement in general health issues, adverse effects of antiepileptic drugs and the relationship with parents. Conclusion: When properly indicated, epilepsy surgery improves quality of life of patients with TLE. Key words: temporal lobe epilepsy, quality of life, surgery.Qualidade de vida e cirurgia de epilepsia na infância e adolescência RESUMO Epilepsia pode afetar a qualidade de vida (QV) de pacientes. A epilepsia de lobo temporal (ELT) é frequentemente refratária ao tratamento medicamentoso, o que tem impacto negativo na QV. A cirurgia pode trazer controle das crises e melhorar a QV de pacientes com epilepsia. Objetivo: O objetivo desse estudo foi verificar a QV de crianças e adolescentes com ELT que foram submetidos à cirurgia para epilepsia, comparando a QV antes e após a intervenção cirúrgica, verificando quais foram os parâmetros que apresentaram melhora. Método: Um questionário semi-estruturado foi aplicado durante a avaliação pré e pós cirúrgica em 13 pacientes. Os dados foram analisados utilizandose o teste de Wilcoxon. Resultados: A análise mostrou que houve melhora global da QV no pós-operatório. Houve melhora em aspectos gerais da saúde, eventos adversos de drogas antiepilépticas e relacionamento com os pais. Conclusão: Quando adequadamente indicada, a cirurgia para epilepsia melhora a QV de pacientes com ELT. Palavras-chave: epilepsia de lobo temporal, qualidade de vida, cirurgia.

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Section: Discussionsupporting

confidence: 88%

Section: Discussionmentioning

confidence: 83%

Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

mentioning

confidence: 99%

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Quality of life and epilepsy surgery in childhood and adolescence

Gagliardi

Guimarães

Souza

et al. 2011

Arq. Neuro-Psiquiatr.

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Abnormal behavior in children with temporal lobe epilepsy and ganglioglioma

Guimarães¹,

Franzon²,

Souza³

et al. 2004

Epilepsy & Behavior

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Epilepsy surgery in low- and middle-income countries: A scoping review

Watila

Xiao

Keezer

et al. 2019

Epilepsy & Behavior

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Background: Epilepsy surgery is an important treatment option for people with drug resistant epilepsy. Although surgical procedures are under-utilized worldwide, it is far worse in Low-and Middle-Income Countries (LMIC) and it is less clear to what extent people with drug resistant epilepsy receive such treatment at all. Here we review the existing evidence for the availability and outcome of epilepsy surgery in LMIC, and discuss some challenges and priority. Methods: We used the six stage methodological framework developed by Arskey and O'Malley as a guide. We searched PubMed, Embase, Global Health Archives, Index Medicus for South East Asia Region (IMSEAR), Index Medicus for Eastern Mediterranean Region (IMEMR), Latin American & Caribbean Health Sciences Literature (LILACS), African Journal Online (AJOL), and African Index Medicus (AIM) to identify the relevant literature. Results: We retrieved 148 articles on epilepsy surgery from 31 countries representing 22% of the 143 LMIC. Epilepsy surgery appears established in some of these centers in Asia and Latin America, while some are in their embryonic stage reporting procedures in a small cohort performed mostly by motivated neurosurgeons. The commonest surgical procedure reported was temporal lobectomies. The post-operative seizure-free rates and quality of life are comparable to those in the high-income countries (HIC). Some models have shown that epilepsy surgery can be performed within a resourcelimited setting through collaboration with international partners and through the use of information and communication technology. The cost of surgery is a fraction of what is available in HIC. Conclusion: This review has demonstrated the availability of epilepsy surgery in few LMIC. The information available is inadequate to make any reasonable conclusion of its existence as routine practice. Collaborations with international partners can provide an opportunity to bring high-quality academic training and technological transfer directly to surgeons working in these regions and should be encouraged.

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Cirurgia para epilepsia na infância: avaliação neuropsicológica e de qualidade de vida

Cited by 9 publications

References 10 publications

Quality of life and epilepsy surgery in childhood and adolescence

Quality of life and epilepsy surgery in childhood and adolescence

Abnormal behavior in children with temporal lobe epilepsy and ganglioglioma

Epilepsy surgery in low- and middle-income countries: A scoping review

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