Epilepsia do lobo temporal com aura de prazer: relato de caso

Tanuri, Fabiano Da Cunha; Thomaz, Rodrigo Barbosa; Tanuri, João Afonso

doi:10.1590/s0004-282x2000000100028

Cited by 10 publications

(2 citation statements)

References 6 publications

(8 reference statements)

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“…While tbMC4R null mice showed a longer latency to mount, a reduced intromission efficiency, and an inability to reach ejaculation, expression of MC4R only on Sim1 neurons reversed these sexual deficits. The amygdala is well known for its involvement in penile erection, sexual sensation, and orgasm in humans (176,226,438). Another possible location for the relevant POMC projections underlying these effects is the PVH.…”

Section: Integrative Sites and Neuronal Networkmentioning

confidence: 99%

Neuroanatomical Framework of the Metabolic Control of Reproduction

Hill

Elias

2018

Physiological Reviews

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A minimum amount of energy is required for basic physiological processes, such as protein biosynthesis, thermoregulation, locomotion, cardiovascular function, and digestion. However, for reproductive function and survival of the species, extra energy stores are necessary. Production of sex hormones and gametes, pubertal development, pregnancy, lactation, and parental care all require energy reserves. Thus the physiological systems that control energy homeostasis and reproductive function coevolved in mammals to support both individual health and species subsistence. In this review, we aim to gather scientific knowledge produced by laboratories around the world on the role of the brain in integrating metabolism and reproduction. We describe essential neuronal networks, highlighting key nodes and potential downstream targets. Novel animal models and genetic tools have produced substantial advances, but critical gaps remain. In times of soaring worldwide obesity and metabolic dysfunction, understanding the mechanisms by which metabolic stress alters reproductive physiology has become crucial for human health.

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Section: Integrative Sites and Neuronal Networkmentioning

confidence: 99%

Neuroanatomical Framework of the Metabolic Control of Reproduction

Hill

Elias

2018

Physiological Reviews

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“…Diversos casos de epilepsia com aura de prazer são relatados na literatura 16,[20][21][22][23] , dentre os quais se destaca o relatado por Cirignotta et al 20 , o primeiro a registrar por eletroencefalografia a descarga epiléptica no lobo temporal.…”

Section: Epilepsia E Alterações Comportamentaisunclassified

Príncipe Liev Nikoláievitch Míchkin ("O Idiota", Fiódor Dostoevsky) e a síndrome de personalidade interictal na epilepsia do lobo temporal

Souza

Mendes

2004

Arq. Neuro-Psiquiatr.

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RESUMO -A obra do romancista russo Fiódor Dostoevsky (1821-1881), além de seu extraordinário valor literário, reveste-se de importância especial para neurologistas e epileptologistas. O escritor, que era portador da enfermidade, transmitiu através de seus textos o universo do epiléptico e a maneira como esse é percebido pela sociedade. Seus livros tiveram grande influência na maneira como a cultura ocidental percebe a doença. O romance "O Idiota" tem como protagonista o Príncipe Liev Nikoláievitch Míchkin, um epiléptico com personalidade marcante. Considerando a proposta feita por Geschwind-Waxman (1975) de síndrome de personalidade interictal na epilepsia do lobo temporal, este artigo pretende discutir as alterações comportamentais no paciente epiléptico a partir de Míchkin, personagem principal de "O Idiota", de Fiódor Dostoevsky.PALAVRAS-CHAVE: epilepsia temporal, Dostoevsky, síndrome de personalidade interictal, síndrome de Geschwind-Waxman.Prince Liev Nikoláievitch Míchkin ("The Idiot", Fiódor Dostoevsky) and the interictal personality syndrome of temporal lobe epilepsy ABSTRACT -Russian romancist Fiódor Dostoevsky's composition, besides its extraordinary literary value, has a special importance for neurologists and epileptologists. The writer, who suffered of epilepsy, transmitted in his texts the epileptic's universe and how the pacient is perceived by the society. His novels had great influence on how epilepsy is perceived by western culture.The romance "The Idiot" has as protagonist Prince Liev Nikoláievitch Míchkin, a epileptic with remarkable personality. Considering the propose made by Geschwind-Waxman (1975) of a interictal personality syndrome in temporal lobe epilepsy, this article intends to discuss the behavioral alterations in epileptic patient, from Míchkin, the main character in Fiódor Dostoevsky's "The Idiot". KEY WORDS: temporal epilepsy, Dostoevsky, interictal personality syndrome, Geschwind-Waxman syndrome.Aparentemente díspares e imiscíveis entre si, arte e ciência compartilham em suas naturezas ampla interface de similaridades: ambas só têm sentido quando situadas dentro de contexto histórico específico; ambas podem abordar o mesmo fenômeno, a mesma verdade, identificando-os, descrevendo-os e interpretando-os, embora de maneira essencialmente distintas. A relação entre arte e ciência pode ser entendida como de complementaridade, e não de simples antagonismo.A obra do romancista russo Fiódor Mikháilovitch Dostoevsky (1821-1881) é emblemática em ilustrar o quanto a arte pode complementar à ciência o nosso entendimento da epilepsia. Os romances do autor, dentre os quais se destacam "Crime e Castigo", "Os Irmãos Karamázovi" e "O Idiota", são marcados pela excelência na descrição psicológica dos personagens, pelo profundo sentimento religioso e pelas reflexões filosóficas. Há, ainda, um outro traço recorrente nos textos do escritor: a epilepsia. O escritor, que sofreu da enfermidade durante várias décadas, traduziu em sua literatura o universo do epiléptico, sua personalidade e a maneira com...

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