Meduloblastomas: achados clínicos, epidemiológicos e anátomo-patológicos de 28 casos

Abstract

We report the clinical, epidemiological and pathological findings of 28 patients with medulloblastoma: 22 were male; age ranged from 1 to 50 years, with a mean of 15 years. The most frequent symptoms and signs were headache (64%) and vomiting (64%). Only one patient showed a desmoplastic medulloblastoma variant, the others showed classical medulloblastomas. Regarding treatment, most patients were submitted to total resection (n=10) or partial tumorectomy (n=7). A low rate of tumoral recurrence was observed, occurring in 21% of the patients (n=6) after 4 years of follow-up. Chemotherapy seemed to contribute to a lower recurrence rate amongst our patients. Our findings are similar to those reported in literature, thus helping to understand the biological behavior of this type of tumor.

Meduloblastoma: correlação entre ressonância magnética convencional, difusão e espectroscopia de prótons

“…Most frequently medulloblastomas occur in children and adolescents, with a remarkable decrease in the incidence at the second and third decades of life (8,9) . For patients in the age range between zero and 19 years, the mean age where the tumor is diagnosed is 7.9 years, with 57.3% of cases occurring between zero and 10 years of age (8) .…”