Massive intracranial immature teratoma: report of a case with polyhidramnios and intense pelvic pain

Soares, Fernando Augusto; Fischer, Sandra E.; Reis, Marlene Antônia dos; Soares, Edson García

doi:10.1590/s0004-282x1996000200021

Cited by 6 publications

(7 citation statements)

References 17 publications

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“…[ 1 ] However, intracranial immature teratomas usually occur in the fetus and frequently cause miscarriage. [ 13 , 14 ] Only a few cases of patients older than 15 years have been reported. [ 2 , 3 ] Here, we present a case of primary intracranial immature teratoma in a 27-year-old woman.…”

Section: Discussionmentioning

confidence: 99%

Intracranial immature teratoma invading the nasal cavity mimicking olfactory neuroblastoma

et al. 2018

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Rationale:Primary intracranial immature teratoma accounts for majority of congenital central nervous system germ-cell tumors, but it is extremely rare in patients older than 15 years.Patient concerns:A 27-year-old woman was referred to our hospital for headache, nasal congestion, and decreased olfactory sensation. Imaging showed a mass measuring approximately 5 cm × 4 cm in the right frontal lobe, which also filled the right nasal cavity. Histopathologically, the intracranial tumor tissues were composed of both mature tissues, including glands and squamous epithelial cells and immature neuroectodermal components. However, the tumor tissues in the nasal cavity were mainly immature neuroectodermal components that mimicked olfactory neuroblastoma. The cells stained positively for neuron-specific enolase, Alpha Thalassemia/Mental Retardation Syndrome X-Linked, and Oligodendrocyte transcription factor on immunostaining, proving a neuroectodermal differentiation.Diagnoses:According to these findings, the tumor was diagnosed as a primary intracranial immature teratoma that also involved the nasal cavity after excluding the metastatic tumors.Interventions:The patient underwent 2 surgeries. The first surgery was via the subfrontal approach, followed by a second endoscopic sinus surgery performed 22 days later.Outcomes:The patient had no recurrence within a 6-month follow-up after the last surgery.Lessons:When an intracranial immature teratoma involves the nasal cavity, the lesions in the nasal cavity may mimic other tumors including olfactory neuroblastoma. We suggest that thorough examination of tumor tissues and identification of variable components are critical for the appropriate diagnosis of intracranial immature teratoma, a rare tumor.

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Section: Discussionmentioning

confidence: 99%

Intracranial immature teratoma invading the nasal cavity mimicking olfactory neuroblastoma

et al. 2018

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“…Therefore, the diagnosis of herniation and increased intracranial pressure can not be considered. In the literature, congenital intracranial teratoma is a rare benign tumor, often in the prenatal period have occurred [1,2]. The teratoma may lead to loss of brain compensatory function, and emergence the neurological symptoms of localized compression or obstruction if rapidly growth.…”

Section: Discussionmentioning

confidence: 99%

“…Huge congenital intracranial teratoma is a rare intracranial benign tumor and often occurs in the prenatal period [1,2]. Computed tomography (CT) and magnetic resonance imaging (MRI) are useful for detecting the localization and delineating the extent of tumor.…”

Section: Introductionmentioning

confidence: 99%

“…Computed tomography (CT) and magnetic resonance imaging (MRI) are useful for detecting the localization and delineating the extent of tumor. Although several studies reported that CT and MRI were a sensitive and specific tools for diagnosing congenital intracranial teratoma in newborn, infant, or stillborn [1][2][3], there has been very little discussion about the details of the radiological features of huge congenital intracranial teratoma in older people. We report the case of an old age patient who was found to have a rare huge congenital teratoma arising in the intracranial brain with brain shift without symptoms, and the present imaging findings are obtained by CT and MRI.…”

Section: Introductionmentioning

confidence: 99%

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Rare Huge Congenital Intracranial Silent Teratoma in Older People: A Case Report

Zhou¹,

Tong²,

Chen³

et al. 2013

AMI

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The huge congenital intracranial teratoma is very rare. We report a case of a 77 years old male with giant congenital brain teratoma without clinical symptoms. His computed tomography (CT) scan showed a massive tumor (6 × 5 × 6 cm) of irregular high density (inside with some point flaky low density) in left temporal lobe region, the lower corner of the left ventricle downward shift, and enhanced CT scan no enhancement. Magnetic resonance imaging (MRI) on brain showed an irregular huge tumor in the left temporal lobe area, with multiple nodular or lobulated mixd high and low or equal signal changes, in which the liquid signal based. The midline was shift to the right, and the posterior horn of the left ventricle was compressed and downward shift, expansion, and hydrocephalus. After follow-up 12 months, the patient presents a normal daily life and work and no neurological signs as usual. Our observations show that the huge tumor in brain with multiple nodular or lobulated variety of mixed signal changes on MRI without symptoms is a congenital intracranial silent teratoma.

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“…There are several cases reported in the literature of stillborn infants presenting with severe macrocephaly, history of polyhydramnios, and even skull rupture at delivery. [7][8][9] Most of these infants die within the first few months of life and the longest survival reported has been 1.5 years. 6 Treatment includes radical surgical resection of the tumor, followed by either radiotherapy and/or chemotherapy.…”

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confidence: 99%

Pathological Case of the Month

Rosario

Ml²,

Ar³

et al. 1999

Arch Pediatr Adolesc Med

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HIS MALE INFANT was born at 41 weeks' gestation to a 20-year-old, gravida 3, para 2 woman with an unremarkable medical history, normal prenatal test results, and no smoking, drug use, or other harmful habits. Pregnancy was complicated by decreased fetal movements during the last week of gestation. An ultrasound performed the morning before delivery revealed severe hydrocephalus. A previous ultrasound performed at the 20th week showed no abnormalities. The infant was delivered by emergency cesarean section without complications or need for resuscitation. Apgar scores were 7 and 9 at 1 and 5 minutes, respectively. His birth weight was 4054 g (Ͼ95th percentile for age), length was 51 cm (75th percentile), and head circumference was 40 cm (Ͼ95th percentile). He was transferred to the neonatal intensive care unit for further evaluation and management. On physical examination the infant had normal vital signs. He had marked macrocephaly, a full anterior

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Massive intracranial immature teratoma: report of a case with polyhidramnios and intense pelvic pain

Cited by 6 publications

References 17 publications

Intracranial immature teratoma invading the nasal cavity mimicking olfactory neuroblastoma

Intracranial immature teratoma invading the nasal cavity mimicking olfactory neuroblastoma

Rare Huge Congenital Intracranial Silent Teratoma in Older People: A Case Report

Pathological Case of the Month

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