Efeitos imediatos dos gangliosídeos cerebrais em neuropatias periféricas: avaliação eletromiográfica

Abstract

The effects of the cerebral cortex gangliosides have been studied in fifteen patients with peripheral neuropathies through the results of electromyographic examination. The patients were divided into two groups: A--peripheral neuropathy of alcoholic etiology (seven patients); D--peripheral neuropathy of diabetes etiology (eight patients). The medication has been administered 20 mg/day intramuscularly during twenty days. At the end of that period it was verified: 1) a discrete increase of the motor conduction velocity in the patients of the group A; 2) the sensitive conduction velocity was inaltered in both groups; 3) a favourable therapeutic response (global evaluation) in three patients of group A, and in three of group D; they represent 40% of the total number of patients studied. For the control of therapeutical effects of the medication the authors suggest a more prolonged period of administration of the medication in hospitalized patients submitted to periodic electromyographic examinations.