Polineuropatias determinadas por tuberculostaticos: estudo da condução nervosa motora em 29 pacientes

Abstract

No presente estudo, procuramos preencher parcialmente esta lacuna relatando a investigação realizada sobre os efeitos destas medicações sobre a condução nervosa motora. MATERIAL E MÉTODOSO estudo foi iniciado com 33 pacientes, admitidos para tratamento de tuberculose pulmonar. Foram retirados do estudo 4 pacientes (um com hepatite e três que pediram alta antes de terminado o estudo). A idade dos pacientes variou entre 16 e 70 anos, com uma média de 36,3 anos, sendo que 23 eram do sexo Trabalho realizado no Sanatório Médico-Cirúrgico do Portão,

Hereditary Neuropathy with Liability to Pressure Palsies Masked by Previous Gunshots and Tuberculosis

“…The third differential diagnosis, complication of tuberculostatic treatment with isoniazid, was excluded, since it was given 14 years earlier and since it was not certain at all that he had received isoniazid without pyridoxine. Although polyneuropathy is a well-known side effect of such a treatment which can be prevented by concomitant pyridoxine treatment [ 5 ], it was excluded because isoniazid neuropathy is not usually associated with such low nerve conduction velocities as reported in our patient [ 6 ]. A plexus lesion was not considered as a differential diagnosis since the distribution of weakness and sensory disturbances argued against such a diagnosis.…”