Acidentes vasculares cerebrais embólicos na cardiopatia chagásica crônica

Nussenzveig, I; Wajchemberg, B. L.; Macruz, R; Netto, Antonio Spina França; Timoner, Júlio; Azul, Luis Gastào do Serro

doi:10.1590/s0004-282x1953000400006

Cited by 19 publications

(6 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The presence of embolic cerebral strokes in chronic chagasic cardiopathy, originally described by Nussenzweig et al (20), has a great clinical importance because it may cause death or severe sequelae. It should be pointed out that in the analysis of the eight cases originally described, the EKG was abnormal in all of them.…”

Section: Discussionmentioning

confidence: 99%

Thromboembolism in chronic Chagas' heart disease

et al. 1995

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Thromboembolism in chronic Chagas' heart disease

et al. 1995

View full text Add to dashboard Cite

show abstract

“…Reports of embolic strokes in chronic chagasic patients have been present in the literature since 1953 [32]. Queiroz [33] reported 26.3% of 114 autopsied patients with chagasic cardiomyopathy presenting ischemic strokes mostly embolic.…”

Section: Chagas Disease and Strokesmentioning

confidence: 99%

Neurologic Manifestations of Chagas Disease

2011

Curr Neurol Neurosci Rep

View full text Add to dashboard Cite

Chagas disease is endemic in Latin America and has become an emerging problem in developed countries because of international migrations. The protozoan Trypanosoma cruzi is the etiologic agent and the disease is divided into two phases. The acute phase is mostly asymptomatic or presents with unspecific symptoms. Rarely, a severe and often fatal form occurs in immunosuppressed patients or infants, characterized by meningoencephalitis (sometimes including brain tumor-like lesions) and myocarditis. The chronic phase consists of an indeterminate, asymptomatic form followed by digestive, cardiac, or neurologic symptoms in about 30% of infected patients. Autonomous nervous system dysfunction is prominent in chagasic patients and participates in the affliction of the target organs. Stroke, mainly cardioembolic, may occur in the chronic phase, but other stroke etiologies are reported. Embolic sources and inflammation are thought to play a role in stroke mechanisms. Specific treatment for Chagas disease is scarce and preventive measures are needed.

show abstract

“…Alencar described cerebral and cerebellar atrophy without any inflammation 17–19 . Even though the existence of direct central nervous system lesions is still disputed, Chagas disease is strongly associated with cardioembolic strokes 20–22 . Other stroke mechanisms are described 23 with some authors suggesting an association between Trypanosome infection and stroke even in the absence of cardiomyopathy or cardiac arrhythmias 24,25 .…”

mentioning

confidence: 99%

Neurological Manifestations in Chagas Disease without Cardiac Dysfunction: Correlation between Dysfunction of the Parasympathetic Nervous System and White Matter Lesions in the Brain

Pedrosa

Silveira

et al. 2009

Journal of Neuroimaging

View full text Add to dashboard Cite

There is a significant correlation between parasympathetic nervous system dysfunction and the presence of white matter lesions in patients with chronic Chagas disease without cardiac dysfunction. The pathogenesis of such lesions is unknown, but cardiac arrhythmias could be involved. As hypertension was frequent in our sample and also correlated to MRI hyperintensities, studies excluding hypertensive patients are needed to confirm our results.

show abstract

Acidentes vasculares cerebrais embólicos na cardiopatia chagásica crônica

Cited by 19 publications

References 2 publications

Thromboembolism in chronic Chagas' heart disease

Thromboembolism in chronic Chagas' heart disease

Neurologic Manifestations of Chagas Disease

Neurological Manifestations in Chagas Disease without Cardiac Dysfunction: Correlation between Dysfunction of the Parasympathetic Nervous System and White Matter Lesions in the Brain

Contact Info

Product

Resources

About