Grading Scale of Visceral Adipose Tissue Thickness and Their Relation to the Nonalcoholic Fatty Liver Disease

Andrade, Luís Jesuíno de Oliveira; Melo, Paulo Roberto Santana de; Paraná, Raymundo; Daltro, Carla

doi:10.1590/s0004-28032014000200009

Cited by 5 publications

(8 citation statements)

References 16 publications

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“…ALL is the most common malignant disease which is associated with high morbidity and mortality rates in children and adults. To increase the survival of patients with ALL several therapeutic approaches have been applied for this disease and recently new drugs for the disease is presented but research on their effectiveness is limited [ 13 14 15 ]. Hyper-CVAD regimen is one of the treatment regimens that were considered by many experts in oncology and blood and had a higher efficacy compared with other studies.…”

Section: Discussionmentioning

confidence: 99%

Evaluate the Response Rate of Acute Lymphocytic Leukemia Patients to Hyper Cyclophosphamide, Vincristine, Adriamycin, and Dexamethasone Regimen and Remission Rate to Stay Until the End of the Arbitrary Treatment

2018

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Background:This study aimed to determine the effect of Hyper-Cyclophosphamide, Vincristine, Adriamycin, and Dexamethasone (CVAD) in the treatment of acute lymphoblastic leukemia (ALL) patients and remission duration.Materials and Methods:During a cross-sectional study in the Seyed Al-Shohada Hospital in Isfahan, patients with ALL who were admitted and treated from 2011 to 2015 because of the risk of ALL were selected and through the records investigation, demographic information, disease information, treatment, remission duration, current status, and duration of survival were collected in the form of data and are sick after going into remission, including the duration and recurrence remission survival time in treatment were analyzed and consequence, whether the patient is going into remission, remission and relapse and survival time based on the duration of treatment were analyzed.Results:Of the 62 patients, 13 patients after starting of treatment did not go to remission and died, but 49 patients (79%) went into complete remission. 21 of them of Hyper-CVAD group and 28 patients of classical treatment group (75/7% vs. 84%), but the difference was not significant (P = 0.43). Of the 48 patients who had a complete remission with the treatment regimen, ten patients relapsed after treatment with two of them of Hyper-CVAD group and eight patients were in the classical treatment group (9/5% vs. 29/6%), and the difference between the two groups was significant (P = 0.015).Conclusion:Hyper-CVAD regimen resulted in increased survival time of patients with ALL and less disease recurrence and therefore contraindications for use if the existing rules, and under the supervision of treatment, can be used.

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Section: Discussionmentioning

confidence: 99%

Evaluate the Response Rate of Acute Lymphocytic Leukemia Patients to Hyper Cyclophosphamide, Vincristine, Adriamycin, and Dexamethasone Regimen and Remission Rate to Stay Until the End of the Arbitrary Treatment

2018

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Section: Methodsmentioning

confidence: 99%

“…Sonographic measurements of adipose tissue were performed including the thickness of perirenal fat (PRFT), and mesenteric fat tissue (MAFT) [15]. The ultrasound PRFT was measured from the inner side of the abdominal musculature to the surface of the kidney [15,16]. The measurement of MAFT was performed with special attention to the identification of the mesenteric leaves appearing as elongated structures—with highly reflective peritoneal surfaces.…”

Section: Methodsmentioning

confidence: 99%

Ultrasonographic Evaluation of Fatty Pancreas in Serbian Patients with Non Alcoholic Fatty Liver Disease—A Cross Sectional Study

Milovanović

Dragašević²,

Lalosevic

et al. 2019

Medicina

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Background and Objectives: The aim of the study was to determine the association between presences of fatty pancreas (FP) with the features of metabolic syndrome (MeS) in patients with non–alcoholic fatty liver disease (NAFLD) and to establish a new noninvasive scoring system for the prediction of FP in patients with NAFLD. Material and Methods: 143 patients with NAFLD were classified according to FP severity grade into the two groups and evaluated for diagnostic criteria of MeS. All patients underwent sonographic examination with adiposity measurements and the liver biopsy. Liver fibrosis was evaluated semi-quantitatively according to the METAVIR scoring system and using non-invasive markers of hepatic fibrosis. Results: Waist circumference (WC) was predictive for increased risk of FP in NAFLD patients. Elevated fasting plasma glucose, total cholesterol, serum amylase and lipase levels were associated with presence of severe FP (p value = 0.052, p value = 0.007, p value = 0.014; p value = 0.024, respectively). Presence of increased amounts of mesenteric fat was associated with severe FP (p value = 0.013). The results of this study demonstrated highly significant association between NAFLD and presence of FP. The model for predicting the presence of FP was designed with probability value above 6.5. Conclusion: Pancreatic fat accumulation leads to worsening of pancreatic function which in turns exacerbates severity of metabolic syndrome associated with both, NAFLD and NAFPD.

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“…That is why the most valuable information is not delivered by a US examination of the thickness of subcutaneous and extraperitoneal fat but rather that of the mesentery. This has been demonstrated in various studies which helped determine that this parameter is an independent risk indicator of severe diseases ( 5 , 7 – 11 ) . Liu et al ( 12 ) , based on a multivariate logistic regression analysis, demonstrated that the value that differentiates normal and thickened mesenteric folds is 10 mm.…”

mentioning

confidence: 83%

“…It turned out that mesenteric fat has the greatest hepatogenic and aterogenic action. It releases multiple lipotoxic substances, such as free fatty acids, adiponectin, tumor necrosis factor (TNF-alpha), plasminogen activator inhibitor type 1 and others, directly to the portal circulation ( 4 – 11 ) . That is why the most valuable information is not delivered by a US examination of the thickness of subcutaneous and extraperitoneal fat but rather that of the mesentery.…”

mentioning

confidence: 99%

Tłuszcz wewnątrzbrzuszny. Część II. Zmiany nienowotworowe tkanki tłuszczowej położonej pozanarządowo

2016

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Adipose tissue does not belong to the most favorite structures to be visualized by ultrasound. It is not, however, free from various pathologies. The aim of this paper is to make abdominal cavity examiners more familiar with non-cancerous lesions found in intra-abdominal fat. The main focus is lesions that are rarely discussed in the literature. Visceral adiposity is one of important pathogenetic factors contributing to cardiovascular events, metabolic syndrome and even certain neoplasms. That is why this article exposes sonographic features that are the most characteristic of these lesions. The value of ultrasonography in the diagnosis of this pathology is underestimated, and a number of US scan reports do not reflect its presence in any way. Moreover, the article discusses more and more common mesenteritis, the lack of knowledge of which could pose difficulties in explaining the nature of symptoms reported by patients. Furthermore, this review presents lesions referred to in the literature as focal infarction of intra-abdominal fat. This section focuses on infarction of the greater and lesser omentum, epiploic appendagitis, mesenteric volvulus and focal fat necrosis resulting from pancreatitis. These lesions should be assessed with respect to the clinical context, and appropriate techniques of ultrasonography should be employed to allow careful determination of the size, shape, acoustic nature and location of lesions in relation to the integuments and large bowel, as well as their reaction to compression with an ultrasound transducer and behavior during deep inspiration. Moreover, each lesion must be obligatorily assessed in terms of blood flow. Doppler evaluation enables the differentiation between primary and secondary inflammation of intra-abdominal fat. The paper also draws attention to a frequent indirect sign of a pathological process, i.e. thickening and hyperechogenicity of fat, which sometimes indicates an ongoing pathology at a deeper site. This structure may completely conceal the primary lesion rendering it inaccessible for ultrasound. In such cases and in the event of other doubts, computed tomography should be the next diagnostic step.

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Grading Scale of Visceral Adipose Tissue Thickness and Their Relation to the Nonalcoholic Fatty Liver Disease

Cited by 5 publications

References 16 publications

Evaluate the Response Rate of Acute Lymphocytic Leukemia Patients to Hyper Cyclophosphamide, Vincristine, Adriamycin, and Dexamethasone Regimen and Remission Rate to Stay Until the End of the Arbitrary Treatment

Evaluate the Response Rate of Acute Lymphocytic Leukemia Patients to Hyper Cyclophosphamide, Vincristine, Adriamycin, and Dexamethasone Regimen and Remission Rate to Stay Until the End of the Arbitrary Treatment

Ultrasonographic Evaluation of Fatty Pancreas in Serbian Patients with Non Alcoholic Fatty Liver Disease—A Cross Sectional Study

Tłuszcz wewnątrzbrzuszny. Część II. Zmiany nienowotworowe tkanki tłuszczowej położonej pozanarządowo

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