Abstract:-Context -There are consistent clues of worse results with grafts from older donors, especially in hepatitis C. University of Wisconsin (UW) solution is adopted for liver preservation, but other solutions are being studied, as fructose-1,6-bisphosphate (FBP). Objective -To determinate the impact of aging of the donor on the cold ischemia injury in rat livers and compare UW and FBP. Methods -Twenty male Wistar rats were studied -10, aging 20 weeks: 5 to preservation with UW (C-UW) and 5, FBP (C-FBP); and other … Show more
In this experimental model of early reperfusion injury, preservation changes related to higher levels of renin, which suggest its role in fibrogenesis. FBP was associated with lower renin levels than other solutions including UW.
In this experimental model of early reperfusion injury, preservation changes related to higher levels of renin, which suggest its role in fibrogenesis. FBP was associated with lower renin levels than other solutions including UW.
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