Randomized clinical trial comparing sodium picosulfate with mannitol on the preparation FOR colonoscopy in hospitalized patients

Muller, Sylviane; Francesconi, Carlos Fernando de Magalhães; Maguilnik, Ismael; Breyer, Helenice Pankowski

doi:10.1590/s0004-28032007000300013

Cited by 17 publications

(25 citation statements)

References 15 publications

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“…The search strategy identified 292 potentially relevant studies, 154 of which were examined in detail and 104 of which were included in the final analysis 10–113 . (see Figure 1).…”

Section: Resultsmentioning

confidence: 99%

“…Group 6 – other comparisons. The remaining studies identified by the literature search 100–112 compared a wide range of differing bowel preparation regimes – generally using bespoke combinations of PEG, NaP, senna, sodium picosulphate or prokinetic agents. Variations in study design and the lack of a constant comparator would make it unhelpful to list the results of these studies, none of which demonstrated any unexpected benefit for one treatment strategy over another.…”

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confidence: 99%

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Meta‐analysis: the relative efficacy of oral bowel preparations for colonoscopy 1985–2010

Belsey¹,

Crosta

Epstein

et al. 2011

Aliment Pharmacol Ther

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“…The search strategy identified 292 potentially relevant studies, 154 of which were examined in detail and 104 of which were included in the final analysis 10–113 . (see Figure 1).…”

Section: Resultsmentioning

confidence: 99%

mentioning

confidence: 99%

Meta‐analysis: the relative efficacy of oral bowel preparations for colonoscopy 1985–2010

Belsey¹,

Crosta

Epstein

et al. 2011

Aliment Pharmacol Ther

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“…The preparations used in inpatient colonoscopy vary from physician to physician (8)(9)(10)(11)(12)(13). Typically, in the acute bleeding patients with a suspected lower gastrointestinal bleed, a purge preparation or no preparation at all (because blood is a purgative to the colon) is used.…”

Section: Preparationmentioning

confidence: 99%

The inpatient Colonoscopy: A Difficult Endeavor

Enns

Krygier

2008

Canadian Journal of Gastroenterology

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The performance of colonoscopy on patients admitted to hospital is a common occurrence. There are a variety of indications for inpatient colonoscopies ranging from acute gastrointestinal bleeding to iron deficiency anemia to occult blood positivity. The practice of colonoscopy for these patients has become relatively commonplace, with most physicians rapidly scheduling the procedure and, in fact, many booking the patient directly to the endoscopy unit and obtaining the full history and consent at the time of the procedure. This practice of inpatient colonoscopy clearly has some advantages with expedited assessment; however, there are a number of issues that limit the benefit of this procedure and may, in some cases, counterbalance the potential gain from the procedure. In the next two sections of 'Ask the Expert' we will present a 'Pro and Con' discussion for inpatient colonoscopy. In contradistinction to most 'Pro/Con' arguments, we have chosen to start with the limitations of colonoscopy in the setting of patients admitted to hospital. The opposing view will be presented in next month's Journal. There is a plethora of literature on inpatient colonoscopy that demonstrates benefit and safety (1-6). At first glance, it seems that colonoscopy is something that should be offered routinely to inpatients without hesitation. Although the benefit has been demonstrated in many studies, most of these have concerned themselves with acute gastrointestinal bleeding. There are a number of reasons why the physician should hesitate before proceeding with an urgent colonoscopy.

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“…In addition, only recently commercially specific colon cleansing products for colonoscopy have become available in Brazil. Several studies have reported on the use of mannitol in Brazil, demonstrating effectiveness in colon preparation, good tolerability and very low complication rates (3,11,16,17,19,24,27) . Methane production in the bowel is poorly understudied.…”

Section: Discussionmentioning

confidence: 99%

SAFETY OF MANNITOL USE IN BOWEL PREPARATION: a prospective assessment of intestinal methane (CH4) levels during colonoscopy after mannitol and sodium phosphate (NaP) bowel cleansing

Paulo

Martins

Macedo

et al. 2016

Arq. Gastroenterol.

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-Background -Adequate bowel preparation is critical for the quality of colonoscopy. Despite reported occurrence of colonic explosion due to methane and hydrogen production by bacterial fermentation during colonoscopy, gas exchange during the procedure is believed to be effective in lowering existing methane concentration, allowing for safe utilization of mannitol for bowel preparation. Thus, mannitol is widely used for bowel cleansing prior to colonoscopy, considering its low cost and effectiveness for bowel preparation.

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Randomized clinical trial comparing sodium picosulfate with mannitol on the preparation FOR colonoscopy in hospitalized patients

Cited by 17 publications

References 15 publications

Meta‐analysis: the relative efficacy of oral bowel preparations for colonoscopy 1985–2010

Meta‐analysis: the relative efficacy of oral bowel preparations for colonoscopy 1985–2010

The inpatient Colonoscopy: A Difficult Endeavor

SAFETY OF MANNITOL USE IN BOWEL PREPARATION: a prospective assessment of intestinal methane (CH4) levels during colonoscopy after mannitol and sodium phosphate (NaP) bowel cleansing

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