Sequential swallows have no influence on esophageal contractions of patients with iron deficiency anemia

Dantas, Roberto Oliveira; Miranda, Adriana Leonarda Martins

doi:10.1590/s0004-28032004000100006

Cited by 3 publications

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References 10 publications

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“…It was stated that the contraction time and amplitude in the esophagus was low. When the initial five consecutive and final five consecutive swallow amplitudes, velocities, and times were compared, there was no significant difference between them [14]. …”

Section: Discussionmentioning

confidence: 99%

Evaluation of Esophageal Functions by Manometry in Iron Deficiency Anemia Patients

2017

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BackgroundThe aim of this study was to investigate whether any esophageal motor dysfunction exists in patients with iron deficiency anemia (IDA).MethodsThe study included 39 patients (34 women, mean age: 44.17 ± 14.21 years) who met WHO diagnostic criteria for IDA. An additional 30 functional dyspepsia patients were also included as a control group. Esophageal motility testing was performed; esophagus contraction amplitude, peak velocity, contraction time, lower esophageal sphincter (LES) resting pressure, LES relaxation, and LES relaxation duration were assessed.ResultsA majority (76.4%) of patients had at least one IDA symptom, such as reflux, chest pain, or dysphagia. Manometric findings in IDA patients vs. controls were as follows: mean LES resting pressure (mm Hg): 25.41 ± 11.67 vs. 19.96 ± 6.58 (P = 0.025); mean esophageal contraction amplitude (mm Hg): 61.61 ± 24.21 vs. 63.23 ± 18.86 (P = 0.764); mean LES relaxation duration (s, x ± SD): 5.33 ± 1.61 vs. 8.75 ± 1.86 (P = 0.000); mean LES relaxation (%): 93.30 ± 9.88 vs. 95.53 ± 5.81 (P = 0.278); mean peak velocity (cm/s): 12.67 ± 37.95 vs. 3.50 ± 1.63 (P = 0.191). Esophageal dysmotility was found in 11 (28.2%) IDA patients. Non-specific esophageal motor disorder was found in three patients, hypomotility of the esophagus was found in three patients, achalasia was found in two patients, hypertensive LES was found in two patients, and hypotensive LES was found in one patient.ConclusionLES resting pressure was higher and LES relaxation duration was shorter in patients with IDA. Esophageal dysmotility was present in 28.2% of the patients with IDA A little more than half of patients had dysphagia symptoms. IDA may contribute to esophageal motility dysfunction and esophageal symptoms.

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Section: Discussionmentioning

confidence: 99%