Diagnosis and Management of Chronic Idiopathic Constipation: A Narrative Review From a Brazilian Expert Task Force

Abstract

Background Chronic idiopathic constipation (CIC) is a condition that widely affects the global population, represents relevant healthcare resource utilization and costs, and impacts the individual’s well-being. Objective To review the consensus of expert societies and published guidelines on the diagnosis and treatment of CIC in adults, seeking to assist reasoning and decision-making for medical management of patients with CIC and provide a practical reference material. Methods A Brazilian medical task force searched the scientific literature in the following electronic databases: MEDLINE/PubMed, SciELO, EMBASE and Cochrane, using the following descriptors: chronic constipation, diagnosis, management of chronic constipation. In addition, a review of articles on the mechanism of action, safety, and efficacy of therapeutic options available in Brazil was carried out. Results The diagnostic approach and the understanding of the pathophysiology present in CIC are essential items to indicate the appropriate therapy and to understand the ecosystem of the patient’s needs. Conclusion CIC is a common condition in adults, occurring more frequently in the elderly and in women. Proper management is defined by detailed medical history and physical examination, together with appropriate therapeutics, regardless pharmacological or not, and depending on the best moment of indication. This way, the impact on quality of life is also optimized.

Alterações intestinais em pessoas com artrite reumatoide

“…É provável que a alimentação dos participantes antes das mudanças tenha contribuído significativamente para a presença de "náusea" e "CI", justificando as alterações realizadas. Além disso, é possível que a idade e o sexo dos entrevistados tenham influenciado na presença proeminente desses sintomas, uma vez que a CI é predominante em mulheres e a idade mais avançada é um fator contribuinte; cabe ressaltar que a CI pode cursar com náuseas (Passos et al, 2022;Eguchi et al, 2021).…”