Comparative analysis of the nuclear lens opalescence by the Lens Opacities Classification System III with nuclear density values provided by Oculus Pentacam: a cross-section study using Pentacam Nucleus Staging software

Magalhães, Fernanda Pedreira; Costa, Elaine Fiod; Cariello, Angelino Júlio; Rodrigues, Eduardo Büchele; Hofling-Lima, Ana Luísa

doi:10.1590/s0004-27492011000200008

Cited by 58 publications

(30 citation statements)

References 14 publications

(18 reference statements)

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“…Full field electroretinography (ERG) examinations were performed in all patients before the injection and 30 days after each injection in order to evaluate the possibility of retinal toxicity. To classify the lens status, the LOCS III (15) classification system was used.…”

Section: Methodsmentioning

confidence: 99%

Intravitreal bevacizumab combined with infliximab in the treatment of choroidal neovascularization secondary to age-related macular degeneration: case report series

Freitas¹,

Isaac²,

Tannure³

et al. 2013

Arq. Bras. Oftalmol.

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Intravitreal bevacizumab combined with infliximab in the treatment of choroidal neovascularization secondary to age-related macular degeneration: case report series ABSTRACTPurpose: To evaluate the feasibility of the combined use of bevacizumab (Avastin ® ) and combined with infliximab (Remicade ® ) in the treatment of naive choroidal neovascularization due to age-related macular degeneration eyes. Methods: Intravitreal injections of bevacizumab combined with infliximab in 6 neovascular age-related macular degeneration eyes. All patients underwent complete ophthalmologic examination on the initial visit and at days 1, 30, 60, 90, 120, 150 and 180 following the first injection. Optical coherence tomography and fluorescein angiography were performed during at initial visit and monthly during the 6 months follow-up period. Electroretinography was performed before and 30 days after initial injection, in order to evaluate retinal toxicity induced by such treatment. Results: Thirty days after the first injection, 5 eyes (83%) shown decrease in macular thickness. No change was seen in electroretinogram in any eyes compared to initially performed electroretinogram. All phakic eyes developed cataract. One patient developed vitritis and was submitted to medical treatment successfully. At the end of the 6 months follow-up period, 4 patients showed significant improvement in the exudative process of choroidal neovascularization. One eye had mild persistent submacular fluid without active choroidal neovascularization, and another eye had persistent amount of intraretinal fluid due to active choroidal neovascularization. Conclusion:The combined use of bevacizumab with infliximab in eyes with neovascular age-related macular degeneration was effective in reducing leakage and improving the macular thickness. However, it is not possible to assert that the results were related to synergic effects of the combination therapy. A controlled study with more cases is necessary to precisely define the complica tion rates; however the dosage and/or association of drugs studied in this research should not be recommended in clinical practice due to cataract as well as inflam matory reaction. Keywords

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Section: Methodsmentioning

confidence: 99%

Intravitreal bevacizumab combined with infliximab in the treatment of choroidal neovascularization secondary to age-related macular degeneration: case report series

Freitas¹,

Isaac²,

Tannure³

et al. 2013

Arq. Bras. Oftalmol.

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“…12 The Pentacam Scheimpflug densitometric method using numerically graded blue light-scattering of the lens layers, was used to measure the nuclear density in the Lens Opacities Classification System (LOCS). 12 Pupillometry was measured by the Colvard Pupillometer (OASIS Medical, Glendora, CA, USA). This precision instrument measures pupillary dilation in low levels of illumination.…”

Section: Flaremeter Kowa Fm-700mentioning

confidence: 99%

Correlation between anterior chamber characteristics and laser flare photometry immediately after femtosecond laser treatment before phacoemulsification

Torun

Pahlitzsch

Klamann

et al. 2016

Eye

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Purpose To assess the anterior chamber (AC) characteristics and its correlation to laser flare photometry immediately after femtosecond laser-assisted capsulotomy and photodisruption.Patients and methods The study included 97 cataract eyes (n = 97, mean age 68.6 years) undergoing femtosecond laser-assisted cataract surgery (FLACS). Three cohorts were analysed relating to the flare photometry directly post femtosecond laser treatment (flare o100 n = 28, 69.6 ± 7 years; flare 100-249 n = 47, 67.7 ± 8 years; flare 4249 photon counts per ms cohort n = 22, 68.5 ± 10 years). Flare photometry (KOWA FM-700), corneal topography (Oculus Pentacam, Germany: AC depth, volume, angle, pachymetry), axial length, pupil diameter, and endothelial cells were assessed before FLACS, immediately after femtosecond laser treatment and 1 day postoperative (LenSx Alcon, USA). Statistical data were analysed by SPSS v19.0, Inc. Results The AC depth, AC volume, AC angle, central and thinnest corneal thickness showed a significant difference between flare o100 vs flare 100-249 10 min post femtosecond laser procedure (P = 0.002, P = 0.023, P = 0.007, P = 0.003, P = 0.011, respectively). The AC depth, AC volume, and AC angle were significantly larger (P = 0.001, P = 0.007, P = 0.003, respectively) in the flare o100 vs flare 4249 cohort 10 min post femtosecond laser treatment. Conclusions A flat AC, low AC volume, and a narrow AC angle were parameters associated with higher intraocular inflammation. These criteria could be used for patient selection in FLACS to reduce postoperative intraocular inflammation.

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“…Experimental in vivo studies, however, were still necessary in order to define the applications and limits of the cavitation bubbles' kinetics and transfer [23]. It is not exactly known where the laser rays vanish, although comparative studies could not demonstrate a relevant clinical impact on the anterior segment of the eye and the retina [6,20].…”

Section: Discussionmentioning

confidence: 99%

“…The intraocular lens calculation was provided by the IOL Master using the SRK/T formula (Zeiss, Meditec AG). The Pentacam Scheimpflug densitometric method, with the blue lightscattering intensity of the lens layers numerically graded, was used to measure the nuclear density in the Lens Opacities Classification System (LOCS) [20,21].…”

Section: Methodsmentioning

confidence: 99%

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Short-term effects of femtosecond laser assisted cataract surgery (FLACS) on central and peripheral cornea thickness

Pahlitzsch¹,

T²

2017

New Front Ophthalmol

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Background: To assess the alterations of the cornea thickness following femtosecond laser assisted cataract surgery (FLACS) compared to the manual phacoemulsification. Methods: Data of n=42 FLACS (66.2 years) and n=40 manual phacoemulsification (71.3 years) were analysed. The procedures were performed by LenSx Alcon and Alcon Infiniti Vision System, USA. The laser setting for performing the anterior capsulotomy (diameter 5 mm) was 4.8 μJ and 8.9 μJ for the nucleus. Following parameters were examined; corneal thickness (Pentacam, Oculus Inc., Germany) at intervals of 0.4 mm to the peripheral 8 mm zone, anterior chamber depth, intraocular pressure and number of endothelial cells (NIDEK CoLtd, Japan). The analysis was performed preoperatively, directly post femtosecond laser treatment (within 15 min) and 1 day post-surgery. Results: A significant difference was not observed in the central and peripheral corneal thickness at any location (p>0.05) in FLACS compared to manual Phaco. As a trend, the complete FLACS cohort showed an increase in the peripheral corneal thickness between 4-8 mm at 1 day postoperative. The peripheral cornea thickness was significantly increased in the female FLACS cohort (4-8 mm, p<0.05). Analysing FLACS and manual Phaco considering the AC depth range of 2.5-3.5 mm could not show significant differences between the two cohorts (p>0.05). Conclusions:The results of this study suggest that conventional laser energy levels did not have a harmful short-term impact on the cornea.

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Comparative analysis of the nuclear lens opalescence by the Lens Opacities Classification System III with nuclear density values provided by Oculus Pentacam: a cross-section study using Pentacam Nucleus Staging software

Cited by 58 publications

References 14 publications

Intravitreal bevacizumab combined with infliximab in the treatment of choroidal neovascularization secondary to age-related macular degeneration: case report series

Intravitreal bevacizumab combined with infliximab in the treatment of choroidal neovascularization secondary to age-related macular degeneration: case report series

Correlation between anterior chamber characteristics and laser flare photometry immediately after femtosecond laser treatment before phacoemulsification

Short-term effects of femtosecond laser assisted cataract surgery (FLACS) on central and peripheral cornea thickness

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