Comparação do efeito analgésico entre etoricoxib 90 mg e dipirona sódica na exérese de pterígio primário com transplante autólogo de conjuntiva

Frantz, Kariza Aiko; Filho, Edney R. Moura; Abud, Murilo Batista; Ávila, Marcos Pereira de; Magacho, Leopoldo

doi:10.1590/s0004-27492009000500012

Cited by 5 publications

(4 citation statements)

References 20 publications

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“…The significant improvement in postoperative visual acuity observed in this study is related to the advanced grades of pterygium which block the visual axis; this effect is reduced postoperatively with proper epithelial healing (13,14) .…”

Section: Discussionmentioning

confidence: 65%

“…The preparation of autologous tissue adhesives using fresh plasma is already done in some blood banks (8,10) . Fibrin glue reduces surgical time, making it an excellent choice for anterior segment surgery and especially for pterygium surgery, which used to be a feared procedure due to postoperative discomfort (11) with symptoms such as burning, foreign body sensation, and dry eye, amongst others (12)(13)(14) .…”

Section: Discussionmentioning

confidence: 99%

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Estudo descritivo de cirurgia de pterígio primário com adesivo de fibrina

Pereira¹,

Vieira²,

Leite³

et al. 2013

Rev. bras.oftalmol.

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RESUMOObjetivo: Avaliar a técnica cirúrgica de exérese de pterígio primário com adesivo de fibrina, quanto à sintomatologia e dados epidemiológicos. Métodos: Ensaio clínico prospectivo, não-controlado e aleatório com 30 pacientes do Hospital Universitário Lauro Wanderley, concordantes com o termo de consentimento livre e esclarecido, aprovado pelo Comitê de Ética em Pesquisa. As cirurgias foram avaliadas nos 1 º , 7 º e 21 º pós-operatório (PO). Resultados: Dos 30 pacientes operados, 16 (53,3%) eram do sexo feminino, com idade variando de 21 a 67 anos (42,2). Quanto à graduação do pterígio (1 a 3): grau 1-10 (33,3%), grau 2-10 (33,3%) e grau 3-10 (33,3%), sendo 16 (53,3%) no olho direito e 14 (46,7%) no olho esquerdo. 56,7% dos pacientes afirmaram intensa exposição solar durante a vida e possuíam casos semelhantes na família. No transoperatório, houve queixas de dor (43,3%) e sensação de corpo estranho (46,7%). O tempo cirúrgico variou de 11 a 32 minutos (17,7). As queixas no 1 º , 7 º e 21 º PO, respectivamente, foram: dor (60%, 26,6% e 6,66%), hiperemia (93,3%, 66,6% e 36,6%), sensação de corpo estranho (53,3%, 46,6% e 20%), epífora (83,3%, 43,3% e 6,66%), secreção (33,3%, 36,6% e 6,66%), ardência (53,3%, 36,6% e 16,6%) e olho seco (6,66%, 26,6% e 23,3%). 43,3% afirmaram estar muito satisfeitos com a cirurgia e 63,8% consideraram o aspecto estético excelente. Três pacientes (10%) não compareceram ao 7 DPO e 5 (16,6%) ao 21 DPO. Não houve perda do enxerto nos casos estudados. Conclusão: O transplante autólogo de conjuntiva é atualmente a alternativa mais eficaz para o tratamento do pterígio. Associado ao uso do adesivo de fibrina, que é composto de fibrinogênio e trombina e tem a vantagem de ser totalmente absorvível, apresenta vantagens, dentre elas a redução do tempo cirúrgico. Neste estudo, corroborando com estudos recentes, o tempo cirúrgico médio foi 19,05 (±6,1) minutos e houve alta incidência de familiares portadores de pterígio e exposição aos raios ultravioleta. A queixa de olho seco aumentou progressivamente após a cirurgia, revelando uma possível alteração do ritmo do piscar. Pouco abordada na literatura, a sintomatologia avaliada neste estudo, mostrou que as queixas leves transoperatórias e acentuadas no 1 º DPO, regrediram a partir do 7 º DPO, justificando a maior satisfação dos pacientes e o excelente aspecto estético referido com o uso desta técnica.Descritores: Pterígio; Transplante autólogo; Espuma de fibrina; Epidemiologia; Sintomas locais (93,3%, 66,6% e 36,6%), foreign body sensation (53,3%, 46,6% e 20%), epiphora (83,3%, 43,3% e 6,66%), discharge (33,3%, 36,6% e 6,66%),burning (53,3%, 36,6% e 16,6%) and dry eye (6,66%, 26,6% e 23,3%

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Section: Discussionmentioning

confidence: 65%

Section: Discussionmentioning

confidence: 99%

Estudo descritivo de cirurgia de pterígio primário com adesivo de fibrina

Pereira¹,

Vieira²,

Leite³

et al. 2013

Rev. bras.oftalmol.

View full text Add to dashboard Cite

show abstract

“…These results also represent an advantage by reducing the potential side effects of those medications. [30][31][32][33][34][35] The main limitation of our study was the small sample size. However, we could still demonstrate a significant difference in the primary end point.…”

Section: Discussionmentioning

confidence: 94%

“…These results also represent an advantage by reducing the potential side effects of those medications. 30–35…”

Section: Discussionmentioning

confidence: 99%

Results of Fibrin Glue Applied Over the Corneal Surface Immediately After Pterygium Surgery: A Novel Pain Relief Technique

Barros

Susanna

Brito

et al. 2023

Cornea

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Purpose:The aim of this study was to compare the use of fibrin glue on the corneal epitheliectomy site at the end of pterygium surgery versus conventional eye patch regarding pain levels, need for oral analgesic medications, number of days feeling pain, and awakening due to pain after surgery.Methods:Forty-eight eyes of 24 patients with bilateral primary pterygium were included in this prospective, randomized, double-masked controlled trial. Each eye of the same patient was randomized to the intervention or control group. The intervention group received 2 drops of fibrin glue in the epitheliectomy site at the end of surgery and an eye patch, whereas the control group was only received an eye patch. Patients returned on the first and seventh days after surgery. Pain intensity (measured using the visual pain analog scale), need for oral analgesics, the number of days the pain lasted, and quality of sleep were assessed during follow-up visits and compared between groups. Comparison analysis accounted for sex, age, pterygium grading, and comorbidities.Results:Visual analog pain scale after surgery was significantly lower in eyes receiving fibrin glue (−1.58; 95% confidence interval: −2.84 to −0.32; P = 0.014). In addition, the intervention group presented a 73% lower chance of using oral analgesics (OR: 0.27; 95% confidence interval: 0.07–0.95; P = 0.041). No difference in the awakenings at night was noted (P = 0.240) nor the mean days of ocular pain in the first week after surgery (P = 0.474).Conclusions:Fibrin glue at the end of pterygium surgery effectively reduces pain and the need for oral analgesics compared with conventional eye patching. This study is the first to describe the results of this strategy.

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Single dose dipyrone (metamizole) for acute postoperative pain in adults

Hearn

Derry²,

Moore³

2016

Cochrane Database of Systematic Reviews

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Based on very limited information, a single dose of dipyrone 500 mg provides good pain relief to about 70% of people treated, compared to about 30% with placebo. For every five people given dipyrone 500 mg, two people would experience this level of pain relief over four to six hours who would not have done with placebo, and fewer people would need rescue medication.We were unable to compare dipyrone directly with other active treatments, or to assess the effects of different doses or routes of administration, or the number of participants experiencing adverse events, because of insufficient data and inadequate reporting.

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Comparação do efeito analgésico entre etoricoxib 90 mg e dipirona sódica na exérese de pterígio primário com transplante autólogo de conjuntiva

Cited by 5 publications

References 20 publications

Estudo descritivo de cirurgia de pterígio primário com adesivo de fibrina

Estudo descritivo de cirurgia de pterígio primário com adesivo de fibrina

Results of Fibrin Glue Applied Over the Corneal Surface Immediately After Pterygium Surgery: A Novel Pain Relief Technique

Single dose dipyrone (metamizole) for acute postoperative pain in adults

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