Amblyopia after unilateral infantile cataract extraction after six weeks of age

Ejzenbaum, Fábio; Salomão, Solange Rios; Berezovsky, Adriana; Waiswol, Mauro; Tartarella, Márcia Beatriz; Sacai, Paula Yuri; Pereira, Josenilson Martins

doi:10.1590/s0004-27492009000500009

Cited by 10 publications

(9 citation statements)

References 21 publications

(17 reference statements)

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“…Therefore, it is quite probable that the visual results were not optimum in this group, due to such late treatment. Our results are comparable to other studies conducted in developing countries such as Brazil, where a study verifies a similar delay in 95.5% of patients with congenital cataract (15) and another study conducted in the same country verified that 88.8% of patients underwent surgery after six months of age (10) . Studies conducted in China showed similar results: one of them reports that 98.8% of patients with unilateral congenital cataract underwent surgery after 6 months, and none of them within the first 12 weeks of age (11) .…”

Section: Discussionsupporting

confidence: 90%

“…The best period for treating the congenital cataract is within the first six weeks of age, for unilateral disease, and within the first 10 weeks of life, for bilateral cases. Bilateral cataract presents a more favorable visual diagnostic as they cause less amblyopia than the unilateral ones (7)(8)(9)(10) . Prevention of blindness caused by congenital cataract depends on early detection and on the availability of specialized equipment and medical staff trained in pediatric ophthalmology.…”

Section: Introductionmentioning

confidence: 99%

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Late diagnosis and surgical treatment of patients diagnosed with unilateral congenital cataract at Fundación Visión, in Asuncion, Paraguay

Zegarra¹,

Burga²,

Lansingh³

et al. 2014

Arquivos Brasileiros De Oftalmologia

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Registered with the fundación visión's ethics committee under number: 002/2013. AbsTRACTPurpose: Providing data on the late diagnosis and surgical treatment of patients who underwent surgery for total unilateral congenital cataract. Methods: Systematic retrospective review of the medical record of all patients between 0 and 16 years old with total unilateral congenital cataract who underwent surgery at Fundación Vision between January 2010 and July 2012. Results: Medical records of 37 patients (51 % females) were studied, age was 7.4 (± 4.9) years (average ± SD) and 62% lived on Departamento Central (the most populated region from Paraguay). A total of 97.3% patients underwent late surgical treatment and 86.5% received a late diagnosis. The average time elapsed between the diagnosis and the surgical treatment was one month, and 62.2% of the patients underwent surgery within six months from the diagnosis. Conclusion: This study evidences that most of the patients in our series had a late treatment as a result of a late diagnosis. Based on these results we recommend establishing strategies to improve the early detection and surgical treatment of the newborns.

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Section: Discussionsupporting

confidence: 90%

Section: Introductionmentioning

confidence: 99%

Late diagnosis and surgical treatment of patients diagnosed with unilateral congenital cataract at Fundación Visión, in Asuncion, Paraguay

Zegarra¹,

Burga²,

Lansingh³

et al. 2014

Arquivos Brasileiros De Oftalmologia

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“…However, the prognosis of patients with amblyopic unilateral CC remains unfavorable, even after surgical intervention at 6 weeks of age. 19 Meanwhile, mean patient age in our study was 73.3 months, indicating that delayed treatment of unilateral CC remains common in China. Thus, better education regarding CC management and a detailed explanation of the potential for poor postoperative visual function for this type of CC are essential for parents of patients with CC.…”

Section: Discussionmentioning

confidence: 65%

Impairments of Visual Function and Ocular Structure in Patients With Unilateral Posterior Lens Opacity

Lin

Chen

Liu

et al. 2018

Trans. Vis. Sci. Tech.

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PurposeWe investigate visual function impairment and ocular structure in patients with unilateral posterior lens opacity, a type of congenital cataract (CC) in our novel CC category system.MethodsWe studied patients aged 3 to 15 years who were diagnosed with unilateral posterior CC. Best corrected visual acuity (BCVA) and visual evoked potentials (VEP) were examined. Corneal astigmatism (CA), mean keratometry, central corneal thickness, anterior chamber depth (ACD), and axial length were measured by Pentacam and IOL-Master. Variations between two eyes were compared by paired t-tests.ResultsAmong the 25 patients involved, BCVAs (logMAR) of cataractous and contralateral healthy eyes were 0.8 ± 0.4 (range, 0.1–1.7) and 0.1 ± 0.1 (range, −0.1 to 0.4). Compared to contralateral healthy eyes, larger CA (1.8 ± 1.2 vs. 0.9 ± 0.4 diopters [D], P = 0.002) and deeper ACD (3.7 ± 0.3 vs. 3.5 ± 0.4 mm, P = 0.009) were found in cataractous eyes. No significant positive or negative linear relationship was found between BCVA and parameters of VEP. Peak time of P100 of pattern VEP-60′ in cataractous eyes was longer than that in contralateral healthy eyes (114.9 ± 18.8 vs. 105.0 ± 12.4 ms, P = 0.013). Amplitudes of P100 of patterns VEP-60′ and -15′ in cataractous eyes were smaller than those in contralateral healthy eyes (PVEP-60′, 15.2 ± 5.3 vs. 19.9 ± 10.4 μV, P = 0.023; PVEP-15′, 10.4 ± 7.0 vs. 22.1 ± 11.9 μV, P = 0.012).ConclusionsImpaired visual function and ocular structure were detected in patients with posterior lens opacities.Translational RelevanceThis study provides evidence-based clinical recommendations for unilateral posterior CC patients with controversial treatment options.

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“…[1][2][3][4][5] For dense congenital unilateral cataracts, surgery during the first 6 weeks of life is associated with improved visual acuity outcomes versus later surgery. 6,7 It has been suggested that every 3 weeks of delay in surgery for dense congenital bilateral cataracts results in an average long-term loss of one line (0.1 logMAR) of visual acuity.…”

mentioning

confidence: 99%

Fixation control and eye alignment in children treated for dense congenital or developmental cataracts

Birch¹,

Wang²,

Felius³

et al. 2011

Journal of American Association for Pediatric Ophthalmology and

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Amblyopia after unilateral infantile cataract extraction after six weeks of age

Cited by 10 publications

References 21 publications

Late diagnosis and surgical treatment of patients diagnosed with unilateral congenital cataract at Fundación Visión, in Asuncion, Paraguay

Late diagnosis and surgical treatment of patients diagnosed with unilateral congenital cataract at Fundación Visión, in Asuncion, Paraguay

Impairments of Visual Function and Ocular Structure in Patients With Unilateral Posterior Lens Opacity

Fixation control and eye alignment in children treated for dense congenital or developmental cataracts

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