2009
DOI: 10.1590/s0004-27492009000400023
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Lúpus discóide em pálpebras: relato de caso

Abstract: Discoid lupus is characterized by erythematosus lesions limited to the skin, covered by adherent white scales, which rise at places more exposed to the sun. A case of a 26 year-old woman, who was suffering for months from redness and burning of the eyes, and was been treated for blepharitis without resolution is reported. On the eyelids exam, ulcerated lesions were found, that were diagnosed as discoid lupus by immunofluorescence. When faced with chronic lesions on the eyelids that do not respond to medical tr… Show more

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Cited by 8 publications
(6 citation statements)
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“…Early diagnosis and treatment can prevent complications such as permanent scarring, entropion, ectropion, adhesion, trichiasis, and visual dysfunction (2,3) . The histopathological findings of eyelid DLE are no different from those of lesions involving other skin sites (7) , with irregular epidermal thickness, vascularisation of the basal layer, dermis with superficial and deep perivascular infiltration with vasodilation, oedema and dissociation of collagen (13) . In our case, the histopathology of eyelid lesions was typical of DLE.…”
Section: Discussionmentioning
confidence: 74%
See 1 more Smart Citation
“…Early diagnosis and treatment can prevent complications such as permanent scarring, entropion, ectropion, adhesion, trichiasis, and visual dysfunction (2,3) . The histopathological findings of eyelid DLE are no different from those of lesions involving other skin sites (7) , with irregular epidermal thickness, vascularisation of the basal layer, dermis with superficial and deep perivascular infiltration with vasodilation, oedema and dissociation of collagen (13) . In our case, the histopathology of eyelid lesions was typical of DLE.…”
Section: Discussionmentioning
confidence: 74%
“…Patients with this presentation will likely be treated as chronic blepharitis or eczema (7) . The differential diagnosis of eyelid DLE includes chronic blepharitis, allergic dermatitis, sarcoidosis, tinea, vitiligo, acne rosacea, lichen planus, psoriasis, cicatricial pemphigoid (1,3,4,11) , basal cell carcinoma, sebaceous gland carcinoma, and lymphoma (4,13) . Early diagnosis and treatment can prevent complications such as permanent scarring, entropion, ectropion, adhesion, trichiasis, and visual dysfunction (2,3) .…”
Section: Discussionmentioning
confidence: 99%
“…A cloroquina por sua vez, além de ser indicada a profilaxia e tratamento de malária causada por Plasmodium vivax, P. ovale e P. malarie (44), também é indicada para o tratamento de amebíase hepática (45), com associação da mesma com outros fármacos pode ter eficácia na artrite reumatoide (46), lúpus eritematoso sistêmico (47), lúpus discoide (48), sarcaidose (49) e doenças fotossensíveis como as erupções polimórficas graves desencadeadas pela luz (50) e porfiria cutânea tardia (51). Com a chegada do novo coronavírus, alguns pesquisadores chineses viram a possível eficácia dessas medicações em pacientes infectados pela forma grave da doença (52).…”
Section: Tratamentounclassified
“…A cloroquina por sua vez, além de ser indicada a profilaxia e tratamento de malária causada por Plasmodium vivax, P. ovale e P. malarie (44), também é indicada para o tratamento de amebíase hepática (45), com associação da mesma com outros fármacos pode ter eficácia na artrite reumatoide (46), lúpus eritematoso sistêmico (47), lúpus discoide (48), sarcaidose (49) e doenças fotossensíveis como as erupções polimórficas graves desencadeadas pela luz (50) e porfiria cutânea tardia (51). Com a chegada do novo coronavírus, alguns pesquisadores chineses viram a possível eficácia dessas medicações em pacientes infectados pela forma grave da doença (52).…”
Section: Tratamentounclassified