Lesões expansivas da órbita: distribuição de casos com estudo histopatológico em 11 anos no Hospital das Clínicas da FMUSP

Neto, Hélio Angotti; Cunha, Leonardo Provetti; Gasparin, Fabio; Santo, Ruth Miyuki; Monteiro, Mário Luiz Ribeiro

doi:10.1590/s0004-27492008000600008

Cited by 2 publications

(1 citation statement)

References 5 publications

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“…In 2008, a study conducted by Angotti-Neto reported similar results in 11-year histopathalogical analysis of orbital tumors. He found that out that of the studied 181 orbital space-occupying lesions, 70% were primary, 23% secondary, 6% metastatic and lymphomas, and 1% was not classified [9].…”

Section: Discussionmentioning

confidence: 99%

Analysis of 1246 Cases of Orbital Lesions: A Study of 17 Years

Khan¹,

Sarwar²,

Sadiq³

et al. 2015

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Purpose: The aim of this study is to present an analysis of orbital lesions by classifying them according to the site of origin in patients of all ages presenting at a tertiary care eye hospital from 1996 till 2012. Methods: 1637 patients were initially enrolled in this descriptive case series. Clinical data of 1246 patients who completed the study during 17 years were analyzed. Orbital lesions of the patients were examined and managed medically or surgically as per requirement. The histopathological reports of these patients were used to classify the lesions. Results: Out of all cases 54.57% (n = 680) were neoplastic and 45.42% (n = 566) were nonneoplastic lesions. Amongst the neoplastic lesions 86.17% (n = 586) were malignant and 13.82% (n = 94) were benign. Primary orbital lesions were the most common orbital lesions being 963 (77.29%) followed by secondary orbital lesions being 232 (18.62%), hematopoietic reticuloendothelial being 47 (3.77%) and metastatic lesions being 04 (0.32%). Conclusion: Orbital lesions are more common in adults as compared to children. Neoplastic lesions are more common than nonneoplastic lesions, and amongst the neoplastic lesions malignant lesions are more common than benign ones. Primary orbital lesions are the most common orbital lesions followed by secondary orbital lesions, lesions of the hematopoietic reticuloendothelial system and metastatic lesions.

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Section: Discussionmentioning

confidence: 99%

Analysis of 1246 Cases of Orbital Lesions: A Study of 17 Years

Khan¹,

Sarwar²,

Sadiq³

et al. 2015

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A Clinical Study on Orbital Tumours in a Tertiary Care Centre in South India

Rani,

Velmurugan,

Anandhi

2023

TNOA Journal of Ophthalmic Science and Research

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Introduction: Space-occupying lesions of the orbit, both benign and malignant, cause significant functional and anatomical problems. A systematic and comprehensive approach is needed for prompt diagnosis and appropriate management of orbital space-occupying lesions. Methods: A total of 50 patients with orbital tumours were enrolled in the study. And it is a cross-sectional study conducted in the Department of Ophthalmology in Tirunelveli Medical College Hospital, Tamilnadu, India, for a time frame of 36 months from January 2018 to January 2021 and a follow up period of 12 months. Results: A total of 50 patients were included in the study. The most common age group involved was 40-60 years, and the mean age was 38 ± 5 years. Females were 40% and males were 60%. In 96% there was unilateral involvement and 4% had bilateral involvement. In the age group under 60 years, 23 eyes had a benign tumour and 11 eyes had a malignant tumour. In the age group of more than 60 years, 14 eyes had a malignant tumour and 2 had a benign tumour. Eccentric proptosis was reported in 85%, and axial proptosis was reported in 15%. In the total study population, 51% of the patients had benign lesions and 49% had malignant lesions. The majority of the cases are treated by chemotherapy alone (39%). The average survival rate is 81% in one year. Discussion: A multimodal systematic approach aids proper diagnosis and also prevents the quandary before commencing treatment. The tumour board discussion in treating every case of a space-occupying lesion plays a vital role in channelizing the case approach. The percentage of malignant tumours increased with age, due to the higher incidence of metastasis in the elderly. Old age tumours should be more suspected of malignancy which can be lifesaving.

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Lesões expansivas da órbita: distribuição de casos com estudo histopatológico em 11 anos no Hospital das Clínicas da FMUSP

Cited by 2 publications

References 5 publications

Analysis of 1246 Cases of Orbital Lesions: A Study of 17 Years

Analysis of 1246 Cases of Orbital Lesions: A Study of 17 Years

A Clinical Study on Orbital Tumours in a Tertiary Care Centre in South India

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