Endoftalmites bacterianas com culturas positivas: uma revisão de 6 anos

Abstract

de sensibilidade à oxacilina, 89,61% à ciprofloxacina e 100% à gatifloxacina e moxifloxacina. A forma de aquisição predominante foi a pós-operatória (60,65%). Conclusão: Observamos baixa sensibilidade da cultura para o diagnóstico etiológico das endoftalmites. Uma terapia antimicrobiana ou profilaxia empírica deve ser ativa contra os microrganismos gram-positivos, particularmente contra estafilococos. Estudos de vigilância de resistência bacteriana são importantes para adequação desses esquemas. RESUMO INTRODUÇÃO

Molecular biology applied to the laboratory diagnosis of bacterial endophthalmitis

“…In clinical cases suspected of endophthalmitis, cultures show a positivity of about 25% to 56% (11)(12)(13)(14)(15) . The low sensitivity of microbiological culture is due to various factors such as small quantity of specimen, fixation of microorganisms in solid surfaces (intraocular lens, lens fragments, capsule) and consequent decrease of cells in the vitreous/aqueous humor, use of antibiotics before the collection of clinical material and the presence of fastidious microorganisms such as agents causing endophthalmitis (14) .…”

Diagnóstico de endoftalmitis por método microbiológico convencional y molecular en pacientes de centros oftalmológicos de Paraguay

“…Los estudios microbiológicos convencionales para el diagnóstico de las endoftalmitis mediante cultivo de humor vítreo, humor acuoso y coloración de Gram, tienen el gran inconveniente de presentar baja sensibilidad. Según los diversos estudios, los cultivos muestran una positividad variable, entre 24% a 56% de los casos sospechosos (16,(22)(23)(24) . En el presente trabajo un 23,5% de las muestras analizadas resultaron ser positivas por el método convencional.…”

Diagnostic Vitrectomy for Infectious Uveitis

“…The sensitivity of culture after diagnostic vitrectomy for the diagnosis of chronic infectious uveitis has been reported between 16.7 to 96% 3, 9, 10, 27 with higher sensitivity reported in case series were there was a high pre-test probability for chronic endogenous or post-operative endophthalmitis. 9 For acute post-operative endophthalmitis, data from the Endophthalmitis Vitrectomy Study showed a yield of 66% for culture and 41% for gram stain for patients undergoing vitrectomy.…”