2002
DOI: 10.1590/s0004-27492002000100005
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Alterações da microbiota conjuntival e palpebral após uso tópico de lomefloxacina e tobramicina na cirurgia de catarata e cirurgia refrativa

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Cited by 10 publications
(13 citation statements)
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“…It is known that the use of prophylactic antibiotics in cataract surgery reduces the number of organisms in the conjunctiva and eyelids (2)(3) , other desirable characteristics are good bioavailability, broad-spectrum coverage and favorable susceptibility patterns (9)(10)(11) . In this study, the most frequently found organism was the CNS, as shown in other studies (8)(9)(13)(14) , this organism is related to approximately 70% of the cases of postsurgical endophthalmitis (15) . There was a low susceptibility rate to neomycin, only 47.4% of the isolates were sensitive to this antibiotic.…”
Section: Discussionsupporting
confidence: 85%
See 1 more Smart Citation
“…It is known that the use of prophylactic antibiotics in cataract surgery reduces the number of organisms in the conjunctiva and eyelids (2)(3) , other desirable characteristics are good bioavailability, broad-spectrum coverage and favorable susceptibility patterns (9)(10)(11) . In this study, the most frequently found organism was the CNS, as shown in other studies (8)(9)(13)(14) , this organism is related to approximately 70% of the cases of postsurgical endophthalmitis (15) . There was a low susceptibility rate to neomycin, only 47.4% of the isolates were sensitive to this antibiotic.…”
Section: Discussionsupporting
confidence: 85%
“…Once superficial flora enters the eye during the cataract surgery, several prophylactic measures are applied to suppress or limit the growth of these microorganisms, which could lead to endophthalmitis. Thus, the use of topical antibiotics before and after cataract surgery is justified as they are efficient in reducing and, sometimes, temporarily eliminating the conjunctival microbiota (2,8) . However, not many studies evaluate the effect of topical antibiotics on endophthalmitis incidence, so the use of these drugs before surgery is considered as probably relevant for infection prophylaxis, but not definitely related to clinical outcome (2) .…”
Section: Introductionmentioning
confidence: 99%
“…Other agents were: S. saprophyticus, Citrobacter ferundii, Enterococcus, Streptococcus (Viridans group), E. coli, Serratia liquefaciens, and Corynebacterium sp., all of which have already been described in several studies assessing the ocular conjunctival flora. (19)(20)(21)(22) The antimicrobial agents to which pathogens were most susceptible were gatifloxacin, vancomycin, tobramycin, and oxacycline, in agreement with the literature. (4,5) It is important to use these agents, as studies show that 82% of the bacteria isolated in postoperative endophthalmitis are genetically identical those isolated from the eyelid and conjunctiva of patients.…”
Section: Interventionsupporting
confidence: 85%
“…No presente estudo, a bactéria mais freqüentemente isolada da conjuntiva dos pacientes foi o estafilococo coagulase negativo, coincidindo com dados publicados an- (8)(9) , inclusive de isolados de endoftalmites (10) . Em um estudo conduzido no Brasil, e recentemente publicado, as bactérias mais freqüentemente isoladas da cultura conjuntival de pacientes sadios foram os grampositivos (88,9%).…”
Section: Discussionunclassified
“…O uso de antibiótico reduziu o número de amostras positivas. (8) Em regime idêntico ao do presente estudo, outros autores sugeriram que a instilação de colírio de ciprofloxacina e ofloxacino diminuiu a contagem de unidades formadoras de colônia (UFC) em relação a um grupo controle com maior redução no grupo que utilizou ciprofloxacina. Nesse estudo, a taxa de positividade da cultura antes da instilação dos antibióticos foi de 65%, sendo o Staphylococcus epidermidis o mais comum.…”
Section: Discussionunclassified