Prevalence of goiter and thyroid nodular disease in patients with class III obesity

Sousa, Priscila Alves Medeiros de; Vaisman, Mário; Carneiro, João Régis Ivar; Guimarães, Lorena; Freitas, Heloisa Maria Pereira; Pinheiro, Maria Fernanda Castellar; Liechocki, Sally; Monteiro, Clarissa Menezes Maya; Teixeira, Patrícia de Fátima dos Santos

doi:10.1590/s0004-27302013000200004

Cited by 48 publications

(47 citation statements)

References 15 publications

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“…A study demonstrated that thyroid volume was positively correlated with body mass index (BMI) [39]; however, the present study did not show this relationship for obese women with prolactinoma.…”

Section: Discussioncontrasting

confidence: 99%

Are there any causes for increased thyroid volume in women with prolactinoma?

Doğan

Taşcı

Arduç

et al. 2015

Annales d'Endocrinologie

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Section: Discussioncontrasting

confidence: 99%

Are there any causes for increased thyroid volume in women with prolactinoma?

Doğan

Taşcı

Arduç

et al. 2015

Annales d'Endocrinologie

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“…Conflicting data exists concerning the effects of TSH on thyroid growth. Some studies observed significant association between serum TSH and thyroid volume [37, 38], although others did not confirm any TSH-related associations [39], suggesting that TSH alone is not a mitogenic factor [40]. Some authors reported that iodine may modulate the thyroid cell response to TSH [41].…”

Section: Discussionmentioning

confidence: 99%

Factors Associated with the Prevalence of Thyroid Nodules and Goiter in Middle-Aged Euthyroid Subjects

Daukšienė

Petkevičienė

Klumbienė

et al. 2017

International Journal of Endocrinology

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The aim of the present study was to determine associations of thyroid hormone levels and different metabolic parameters and anthropometric measurements with volume of nodular and nonnodular thyroid as well as with prevalence of goiter and thyroid nodules in middle-aged euthyroid subjects. Methods. The study consisted of 317 euthyroid subjects aged 48-49 from the Kaunas Cardiovascular Risk Cohort study. Thyroid-stimulating hormone (TSH), free thyroxine (FT4), and antithyroid peroxidase antibody (ATPO) levels, as well as anthropometric and metabolic parameters and smoking information, were evaluated. Results. In subjects with and without thyroid nodules, thyroid volume correlated with components of metabolic syndrome, body mass index (BMI), smoking, and TSH levels. In the nonnodular thyroid group, thyroid volume was also positively related to serum insulin and HOMA-IR, whereas a negative correlation between thyroid volume and leptin was identified in the nodular thyroid group. The goiter was identified in 12.3% of subjects. Female gender, thyroid nodules, smoking, BMI, and levels of TSH were independent predictors for goiter. Thyroid nodules were found in 31.2% of participants. Female gender, higher TSH levels, and thyroid volume were independent risk factors for thyroid nodules. Conclusions. Female gender, thyroid nodules, smoking, BMI, and TSH levels were identified as potential predictors of goiter. Female gender, TSH levels, and thyroid volume predicted the presence of thyroid nodules.

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“…In HD patients, ultrasonography of the thyroid gland was performed on a day between dialysis. Enlargement of the thyroid gland was defined as a thyroid volume exceeding 10 or 12 cm 3 in female and male subjects, respectively …”

Section: Methodsmentioning

confidence: 99%

“…ment of the thyroid gland was defined as a thyroid volume exceeding 10 or 12 cm 3 in female and male subjects, respectively. 8,9…”

Section: Hemodialysis International 2015; ••:••-••mentioning

confidence: 99%

High prevalence of subclinical hypothyroidism and nodular thyroid disease in patients on hemodialysis

Costa

Pellizzari

Carvalho

et al. 2015

Hemodialysis International

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Chronic kidney disease has been known to affect thyroid hormone metabolism. Low serum levels of T3 and T4 are the most remarkable laboratorial findings. A high incidence of goiter and nodules on thyroid ultrasonography has been reported in patients with end-stage renal disease (ESRD). Our objective is to evaluate the prevalence of laboratorial and morphologic alterations in the thyroid gland in a cohort of patients with ESRD on hemodialysis (HD). Sixty-one patients with ESRD on HD were selected and compared with 43 healthy subjects matched by age, gender, and weight. Patients were submitted to thyroid ultrasonography. T3, free T4 (FT4), thyroid-stimulating hormone, antithyroglobulin, and antithyroperoxidase antibodies were measured. The mean age of patients with ESRD was 47.4 ± 12.3 and 61% were women. ESRD was mainly caused by hypertensive nephrosclerosis and diabetic nephropathy. Mean thyroid volume, as determined by ultrasonography, was similar in both groups. Patients with ESRD had more hypoechoic nodules when compared with the control group (24.1% vs. 7.9%, P = 0.056). Mean serum FT4 and T3 levels were significantly lower in patients with ESRD, and subclinical hypothyroidism was more prevalent in patients with ESRD (21.82% vs. 7.14% control group, P = 0.04). Titers of antithyroid antibodies were similar in both groups. ESRD was associated with a higher prevalence of subclinical hypothyroidism and lower levels of T3 and FT4. Almost a quarter of patients showed thyroid nodules >10 mm. Periodic ultrasound evaluation and assessment of thyroid function are recommended in patients with ESRD on HD.

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Prevalence of goiter and thyroid nodular disease in patients with class III obesity

Cited by 48 publications

References 15 publications

Are there any causes for increased thyroid volume in women with prolactinoma?

Are there any causes for increased thyroid volume in women with prolactinoma?

Factors Associated with the Prevalence of Thyroid Nodules and Goiter in Middle-Aged Euthyroid Subjects

High prevalence of subclinical hypothyroidism and nodular thyroid disease in patients on hemodialysis

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