Raquitismo hipofosfatêmico: da clínica à genética molecular

Nunes, Ana Carla Robatto; Lazaretti‐Castro, Marise

doi:10.1590/s0004-27302000000200004

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May Values Change According To Sample Collection Habits and Characteristics Of A Country's Population?1

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2021

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“…According to the habits and behavior of the Brazilian population, sunscreen use may be associated with lowest 25 (OH) vitamin D levels in comparison with sunlight-exposed subjects. 21 In addition, genetic features play a role, since it is known that the phosphate-regulating gene with homologies to endopeptidases on the X chromosome (PEX) alters the function of one of the proteins acting on phosphate regulation, which is closely linked to the diagnosis of rickets due to hypovitaminosis D. 57 Therefore, it is essential to consider behaviors and even clinical issues from each patient to determine whether there is a diagnosis of vitamin deficiency or if these are only factors inducing the condition.…”

Section: May Values Change According To Sample Collection Habits and Characteristics Of A Country's Population?mentioning

confidence: 99%

Vitamin D Deficiency in Brazil: Questions about Potential Causes and Clinical Characteristics*

Vieira

Ferreira

Giacomelli

et al. 2021

International Journal of Nutrology

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Vitamin D is a micronutrient essential to various systems from the human body, and it is not restricted to the classical function of bone mineralization. Its synthesis is mainly related to ultraviolet B (UVB) radiation exposure. Although Brazil is a tropical country with high levels of UVB radiation, counter-intuitively, a large number of Brazilians present vitamin D deficiency, which is also a worldwide issue. This review aims to approach clinical features and explore potential causes for this apparent contradiction through questions that could explain vitamin D deficiency in the Brazilian population.

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Section: May Values Change According To Sample Collection Habits and Characteristics Of A Country's Population?mentioning

confidence: 99%