Abstract:Purpose
To investigate the efficacy of cordycepin, an adenosine analogue, on
prevention of esophageal damage and stricture formation due to esophageal
caustic burns in rat model comparing with prednisolone.
Methods
Caustic esophageal burn was introduced by 37.5% of NaOH to distal esophagus.
Thirty-two Wistar albino rats were divided in four groups: sham rats
undergone laparotomy, treated with 0.9% NaCl; control rats injured with NaOH
without cordycepin treatment; cordyc… Show more
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