“…This is apparent by substantial work that has been carried out in developing machine-learning models, and deep-learning techniques to process high-dimensional MRI data to model neural pathways that govern the brains of various mental disorders (Vieira et al, 2017). These efforts have resulted in development of machine-learning methods to classify Alzheimer's, Mild Cognitive impairment (Duchesnay et al, 2011), Temporal Lobe Epilepsy, Schizophrenia, Parkinson (Bind et al, 2015), Dementia (Ye et al, 2011;Ahmed et al, 2018;Pellegrini et al, 2018), ADHD (Eslami and Saeed, 2018b;Itani et al, 2019), ASD (Pagnozzi et al, 2018;Hyde et al, 2019), and major depression (Gao et al, 2018). These machine-learning models rely on statistical algorithms, and are suitable for complex problems involving combinatorial explosion of possibilities or non-linear processes where traditional computational models fail in quality or scalability.…”