Estimulação elétrica no tratamento da hipossalivação induzida pela radioterapia

Paim, Émille Dalbem; Berbert, Monalise Costa Batista; Zanella, Virgílio Gonzales; Macagnan, Fabrí­cio Edler

doi:10.1590/2317-1782/20192018176

Cited by 6 publications

(5 citation statements)

References 28 publications

(54 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…These interventions have mainly been proven in breast [28][29][30][31] and colorectal cancer [32,33]. With regard to HNC survivors, electrotherapy such as transcutaneous electrical nerve stimulation (TENS) [37,38] and laser therapy [39] have reported promising results on salivary flow rate and QoL. Even acupuncture has shown only a discrete effect, increasing salivary function in patients after RT [40].…”

Section: Introductionmentioning

confidence: 99%

Effect of Physical Therapy Modalities on Quality of Life of Head and Neck Cancer Survivors: A Systematic Review with Meta-Analysis

Burgos-Mansilla

Galiano‐Castillo

Lozano‐Lozano

et al. 2021

JCM

View full text Add to dashboard Cite

The objective was to describe the effectiveness of different physical therapy modalities to improve Quality of Life (QoL) in Head and Neck Cancer (HNC) survivors. PubMed, Scopus, Web of Science, CINAHL and Cochrane Library were searched for randomized clinical controlled trials published until 30 April 2020. Risk of bias assessment and meta-analysis were conducted using the Cochrane tools. A total of 251 records were retrieved, and 10 met the inclusion criteria. Interventions whose parameters focus on a 12-week exercise programs of aerobic activity (walking) or Progressive Resistance Training (PRT) for the whole body are effective and safe modalities improving QoL in HNC survivors. Electrophysical agents did not show significant results between groups. As for the assessment of methodological quality, 4 of the 10 articles included had a high risk of overall bias. Only five articles provided sufficient information to conduct a meta-analysis for exercise program intervention on QoL, showing a tendency in favor of intervention group, even when the global results did not show statistically significant improvements (pooled Cohen’s d 0.15; 95% CI: −0.25 to 0.54; I2 45.87%; p heterogeneity = 0.10). The present review and meta-analysis identified meaningful benefits of exercise on QoL of HNC survivors; this has been confirmed in a meta-analysis. This review adds evidence supporting exercise interventions on Head and Neck Cancer population whose opportunities for successful recovery after medical treatment are more limited.

show abstract

Section: Introductionmentioning

confidence: 99%

Effect of Physical Therapy Modalities on Quality of Life of Head and Neck Cancer Survivors: A Systematic Review with Meta-Analysis

Burgos-Mansilla

Galiano‐Castillo

Lozano‐Lozano

et al. 2021

JCM

View full text Add to dashboard Cite

show abstract

“…Salivary acini are highly radiosensitive, in a way that radiotherapy can culminate in apoptosis, necrosis, impaired signaling between cell and receptor, inflammation, edema and vascular changes. Radiotherapy interferes with the signaling process of afferent and efferent fibers in the autonomic nervous system, which participate in the saliva production, affecting the salivary production 11 . Thus, patients tend to present discomfort and difficulty performing basic functions (taste, chewing, swallowing, difficulty with speech) 4 .…”

Section: Resultsmentioning

confidence: 99%

Salivary Flow Analysis of Head and Neck Irradiated Patients

Baldo

Freitas

Carvalho³

et al. 2021

J. Health Scie.

View full text Add to dashboard Cite

This study aimed to analyze the salivary flow of irradiated patients for the head and neck cancer treatment after the conclusion of their treatment, and to compare it to the salivary flow of a group of non-irradiated patients. The salivary flow measurement was performed using the stimulated saliva analysis technique by masticatory action. The data collected were organized in planning using the Microsoft Excel program and then analyzed through the program IBM SPSS 20.0. The independent T-test was used to compare the median values between the groups that had normal distribution. 54 patients were evaluated, 18 from Group 1, of irradiated patients with an average time of ending radiotherapy of 11 months; and 36 patients from Group 2, with non-cancerous and non-irradiated patients. The mean salivary flow of Group 1 patients was 0.39 (± 0.85) and 100% of the patients expelled less than 3.5mL of saliva after stimulation for five minutes. Among the patients from Group 2, the mean salivary flow was 3.22 (± 2.65), and 77.78% of the patients had a salivary stimulation of less than 3.5 mL. This difference was statistically significant (p = 0.004). Through the methodology used, a high prevalence of hyposalivation was observed in patients irradiated in head and neck for cancer treatment even after months of the treatment conclusion and among patients without cancer and not submitted to radiotherapy. However, a deficiency in saliva production was statistically higher among patients irradiated in the head and neck. Keywords: Neoplasms. Radiotherapy. Saliva. Xerostomia. ResumoEste estudo teve como objetivo analisar o fluxo salivar de pacientes irradiados no tratamento do câncer de cabeça e pescoço após a conclusão de seu tratamento, e compará-lo com o fluxo salivar de um grupo de pacientes não irradiados. A medição do fluxo salivar foi realizada utilizando a técnica de análise de saliva estimulada por ação masticatória. Os dados coletados foram organizados no planejamento utilizando o programa Microsoft Excel e, em seguida, analisados através do programa IBM SPSS 20.0. O teste T independente foi utilizado para comparar os valores medianos entre os grupos que apresentaram distribuição normal. Foram avaliados 54 pacientes, 18 do Grupo 1, de pacientes irradiados com tempo médio de término da radioterapia de 11 meses; e 36 pacientes do Grupo 2, com pacientes não cancerosos e não irradiados. O fluxo salivar médio dos pacientes do Grupo 1 foi de 0,39 (± 0,85) e 100% dos pacientes expeliram menos de 3,5 mL de saliva após estimulação por cinco minutos. Entre os pacientes do Grupo 2, o fluxo salivar médio foi de 3,22 (± 2,65), e 77,78% dos pacientes apresentaram estimulação salivar inferior a 3,5 mL. Essa diferença foi estatisticamente significante (p = 0,004). Por meio da metodologia utilizada, observou-se alta prevalência de hiposalivação em pacientes irradiados na cabeça e pescoço para tratamento de câncer mesmo após meses da conclusão do tratamento e entre pacientes sem câncer e não submetidos à radioterapia. No entanto, a deficiência na produção de saliva foi estatisticamente maior entre os pacientes irradiados na cabeça e pescoço. Palavras-chave: Neoplasias. Radioterapia. Saliva. Xerostomia.

show abstract

“…Cuando la capacidad secretora residual de las glándulas salivales aún está presente, puede ser apropiada la estimulación de la secreción salival 46 . Entre las opciones reportadas en la literatura están los fármacos parasimpaticomiméticos, la acupuntura, la fitoterapia, la estimulación nerviosa y la PBMT 38,[45][46][47][48][49][50][51][52][53][54][55][56][57][58] .…”

Section: Manejo Terapéutico Para La Xerostomíaunclassified

“…Existen dos tipos de TENS: la TENS convencional que consiste en la estimulación local de las glándulas salivales y la TENS similar a la acupuntura que consiste en la estimulación a distancia 53,54 . Estudios han demostrado que ambos tipos de TENS son eficaces y seguros para disminuir la xerostomía inducida por radioterapia 55,56 .…”

Section: Manejo Terapéutico Para La Xerostomíaunclassified

Manejo odontológico de las manifestaciones orales inducidas por radioterapia de cabeza y cuello

Mejía-Chuquispuma

Flores-Jiménez

Castro-Auqui

et al. 2023

View full text Add to dashboard Cite

La radioterapia es una de las primeras opciones de tratamiento para el cáncer de cabeza y cuello; sin embargo, puede ocasionar diversas manifestaciones secundarias en la cavidad oral tales como mucositis oral, xerostomía, infecciones orales oportunistas, osteorradionecrosis y trismo. El presente artículo tiene como objetivo describir el manejo preventivo y terapéutico de las complicaciones orales inducidas por radioterapia de cabeza y cuello en la práctica odontológica propuestos hasta la actualidad. Se encontraron diversas medidas que han logrado reducir la incidencia y gravedad de dichas manifestaciones orales; sin embargo, aún existen algunas que requieren de más estudios para confirmar su efectividad. Palabras clave: cáncer de cabeza y cuello; manifestaciones bucales; radioterapia; terapéutica.

show abstract

Estimulação elétrica no tratamento da hipossalivação induzida pela radioterapia

Cited by 6 publications

References 28 publications

Effect of Physical Therapy Modalities on Quality of Life of Head and Neck Cancer Survivors: A Systematic Review with Meta-Analysis

Effect of Physical Therapy Modalities on Quality of Life of Head and Neck Cancer Survivors: A Systematic Review with Meta-Analysis

Salivary Flow Analysis of Head and Neck Irradiated Patients

Manejo odontológico de las manifestaciones orales inducidas por radioterapia de cabeza y cuello

Contact Info

Product

Resources

About