Trees with high levels of growth stress begin to show log end splits (LES) immediately after harvesting, usually reaching its maximum end split in a week, and these tensions also create splits during lumber manufacturing. Interlocked grain is another characteristic that impacts the properties of eucalyptus wood. The aim of this study was to evaluate the effect of growth stress and interlocked grain patterns on log end splitting of seven different hybrid clones of Eucalyptus grandis × Eucalyptus urophylla planted in Brazil. The growth stress indicator (GSI) was measured in standing trees before harvesting. Splits were measured on logs in three different stages, and interlocked grain from wood blocks was obtained across the center of the cross-section. The results showed that LES occurred as soon as the trees were harvested; however, for better selection of clones, LES should be evaluated after a week of harvesting. There were statistically significant correlations for GSI with LES. Clones that presented higher values of interlocked grain tended to develop lower values of GSI and LES. Using GSI and interlocked grain measurements, it was possible to select the most indicated eucalyptus clones for lumber production.