Good practices recommendations from the Brazilian Society of Nephrology to Peritoneal Dialysis Services related to the new coronavirus (Covid-19) epidemic

Calice‐Silva, Viviane; Cabral, Alexandre Silvestre; Bucharles, Sérgio Gardano Elias; Moura-Neto, José A.; Figueiredo, Ana Elizabeth; Franco, Ricardo Portiolli; Pio-Abreu, Andrea; Nascimento, Marcelo Mazza do

doi:10.1590/2175-8239-jbn-2020-s106

Cited by 8 publications

(6 citation statements)

References 6 publications

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“…Considering the hazardous context of SARS-CoV-2 infection, in order to attenuate the spread of the virus in CKD patients undergoing dialysis, a series of safety measures were adopted by hemodialysis centers and clinics to efficiently operate throughout the pandemic (Table 2) [65][66][67][68][69][70][71][72] . Nonetheless, Corbett et al in a cohort study evaluating the epidemiology of COVID-19 in dialysis centers in the United Kingdom revealed that COVID-19 caused an abrupt epidemic in patients and healthcare workers.…”

Section: Patients With Ckd In Dialytic Therapy and Covid-19mentioning

confidence: 99%

COVID-19 and chronic kidney disease: a comprehensive review

et al. 2021

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Kidney impairment in hospitalized patients with SARS-CoV-2 infection is associated with increased in-hospital mortality and worse clinical evolution, raising concerns towards patients with chronic kidney disease (CKD). From a pathophysiological perspective, COVID-19 is characterized by an overproduction of inflammatory cytokines (IL-6, TNF-alpha), causing systemic inflammation and hypercoagulability, and multiple organ dysfunction syndrome. Emerging data postulate that CKD under conservative treatment or renal replacement therapy (RRT) is an important risk factor for disease severity and higher in-hospital mortality amongst patients with COVID-19. Regarding RAAS blockers therapy during the pandemic, the initial assumption of a potential increase and deleterious impact in infectivity, disease severity, and mortality was not evidenced in medical literature. Moreover, the challenge of implementing social distancing in patients requiring dialysis during the pandemic prompted national and international societies to publish recommendations regarding the adoption of safety measures to reduce transmission risk and optimize dialysis treatment during the COVID-19 pandemic. Current data convey that kidney transplant recipients are more vulnerable to more severe infection. Thus, we provide a comprehensive review of the clinical outcomes and prognosis of patients with CKD under conservative treatment and dialysis, and kidney transplant recipients and COVID-19 infection.

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Section: Patients With Ckd In Dialytic Therapy and Covid-19mentioning

confidence: 99%

COVID-19 and chronic kidney disease: a comprehensive review

et al. 2021

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“…On the contrary, PD patients, received telemedicine consultation during the COVID-19 pandemic. 24 Moreover, telehealth has played a pivotal role in the current pandemic and should be implemented whenever possible; however, the quality of evidence is controversial. [25][26] Studies evaluating the impact of COVID-19 on PD and HD patients have conflicting results 2,8,22,23,27 .…”

Section: Discussionmentioning

confidence: 99%

Clinical outcomes of COVID-19 in patients undergoing chronic hemodialysis and peritoneal dialysis

Gorayeb-Polacchini¹,

Caldas²,

Abbud-Filho³

2022

Braz. J. Nephrol.

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Background: The reported incidence and fatality rate of the severe acute respiratory syndrome coronavirus 2 in patients receiving chronic dialysis are higher than in the general population. We sought to study the outcomes following coronavirus disease 2019 (COVID-19) diagnosis in patients undergoing chronic hemodialysis (HD) or peritoneal dialysis (PD) in a single center in Brazil. Methods: Of the 522 patients on dialysis evaluated between March 1, 2020, and October 1, 2021, those presenting symptoms or with a history of close contact with COVID-19 patients were tested with reverse-transcription polymerase chain reaction of samples from nasopharyngeal swabs. Results: Of the 522 patients, 120 were positive for COVID-19 infection, of which 86% were on HD and 14% in the PD program. The incidence per 10,000 inhabitants was higher in the HD group than in the PD group (2,423.5 vs. 1,752.5). The mortality per 10,000 inhabitants (470.5 vs. 927.8) and the fatality rate (19.4 vs. 52.9%, p = 0.005) were higher in the PD group. The PD group also had a higher need for hospitalization, intensive care, and mechanical ventilation. Conclusions: We advise caution when considering strategies to transfer patients from HD to the PD program to minimize the risk of COVID-19 for patients on HD.

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“…O grupo HD não conseguiu aderir às recomendações de isolamento, e 16% relatou ter tido contato com a COVID-19 no transporte público a caminho da unidade de diálise. Pelo contrário, os pacientes em DP, receberam consulta por telemedicina durante a pandemia da COVID-19 24 . Além disso, a telessaúde tem desempenhado um papel crucial na atual pandemia e deve ser implementada sempre que possível; no entanto, a qualidade das evidências é controversa 25,26 .…”

Section: Discussionunclassified

Desfechos clínicos da COVID-19 em pacientes submetidos à hemodiálise crônica e diálise peritoneal

Gorayeb-Polacchini¹,

Caldas²,

Abbud-Filho³

2022

Braz. J. Nephrol.

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Resumo Antecedentes: A incidência e a taxa de letalidade da síndrome respiratória aguda grave por coronavírus 2 relatadas em pacientes em diálise crônica são mais elevadas do que na população em geral. Procuramos estudar os desfechos após o diagnóstico da doença por coronavírus 2019 (COVID-19) em pacientes submetidos à hemodiálise crônica (HD) ou diálise peritoneal (DP) em um único centro no Brasil. Métodos: Dos 522 pacientes em diálise avaliados entre 1º de Março de 2020 e 1º de Outubro de 2021, aqueles que apresentaram sintomas ou tiveram histórico de contato próximo com pacientes com COVID-19 foram testados com reação em cadeia da polimerase de transcrição reversa por meio de amostras de esfregaços nasofaríngeos. Resultados: Dos 522 pacientes, 120 foram positivos para infecção por COVID-19, dos quais 86% estavam em HD e 14% no programa de DP. A incidência por 10.000 habitantes foi maior no grupo HD do que no grupo DP (2.423,5 vs. 1.752,5). A mortalidade por 10.000 habitantes (470,5 vs. 927,8) e a taxa de letalidade (19,4 vs. 52,9%, p = 0,005) foram mais elevadas no grupo DP. O grupo DP também apresentou uma maior necessidade de hospitalização, terapia intensiva e ventilação mecânica. Conclusões: Recomendamos cautela ao considerar estratégias de transferência de pacientes do programa de HD para o de DP a fim de minimizar o risco de COVID-19 para pacientes em HD.

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Good practices recommendations from the Brazilian Society of Nephrology to Peritoneal Dialysis Services related to the new coronavirus (Covid-19) epidemic

Cited by 8 publications

References 6 publications

COVID-19 and chronic kidney disease: a comprehensive review

COVID-19 and chronic kidney disease: a comprehensive review

Clinical outcomes of COVID-19 in patients undergoing chronic hemodialysis and peritoneal dialysis

Desfechos clínicos da COVID-19 em pacientes submetidos à hemodiálise crônica e diálise peritoneal

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