Mycobacterium abscessus urinary tract infection: case report

Abstract

Urinary tract infection is a serious public health issue that predominantly affects women. In men, it is more often associated with prostatic hyperplasia and bladder catheterization. Urogenital tuberculosis presents with nonspecific with nonspecific symptoms and the diagnosis can be made in the presence of sterile leukocyturia and recurrent infection with acid urine. Non-tuberculous mycobacteria or other non-tuberculosis mycobacteria are opportunistic pathogens that inhabit the soil, water or environment surfaces, and usually cause diseases in immunocompromised individuals. Mycobacterium abscessus is an agent that causes lung, skin and soft tissue hospital infections. Urinary tract infections by this pathogen are rare.

Mycobacterium abscessus urinary tract infection in an immunocompetent host: A case report and literature review

“…Genitourinary infections caused by NTM are infrequent, and only a few cases have been reported [5] . Even rarer, genitourinary infections related to MABC have been identified [5] , [6] , [7] , [8] . Our patient has a history of multiple admission and previous invasive urological instrumentation, which supports the hypothesis that invasive procedures can increase the risk of acquiring NTM related genitourinary infections [12] .…”

“…Given its rarity, the data regarding UTI secondary to M. abscessus is limited [5] , [6] , [7] , [8] . Based on a retrospective study of 15 patients with NTM genitourinary infections, chronic kidney disease (CKD) was the most common associated pre-existing condition.…”

“…Only two patients reported positive urine AFB smears [7] , [8] . Imipenem-cilastatin and amikacin were mainly used as injectable agents in 80% of the cases [5] , [6] , [8] . Of the cases identified, two were associated with prostatic abscess and drainage was required [5] .…”

“…Urinary tract infection (UTI) secondary to M. abscessus is an extremely rare condition [4] . To the best of our knowledge, only five Mycobacterium abscessus complex (MABC) UTI cases are reported in the literature [5] , [6] , [7] , [8] . Herein, we report a complicated case of UTI secondary to M. abscessus in an immunocompetent adult, which was successfully treated with a long course of combined antimicrobial agents.…”

Mycobacterium Avium Complex Genitourinary Infections: Case Report and Literature Review

“…In our patient, she has grown multiple bacterial organisms in the urine cultures over the years including Candida species with some improvement in symptoms until the next recurrence. Other NTM (M. abscessus, M. fortuitum, M. gordonae) causing genitourinary infection do not have a similar presentation [21][22][23][24][25][26][27].…”