Can natural products improve skin photoprotection?

Abstract

Due to increased UV radiation on the Earth’s surface, caused by depletion of the stratospheric ozone, people have become more susceptible to different types of skin damage, such as erythema, sunburns, and cancer; this is especially of concern in tropical countries. Thus, efforts to improve awareness as well as the use of sunscreen are increasing worldwide. However, synthetic UV filters have been associated with deleterious effects such as photosensitization. Natural products have been used by ancient cultures for several purposes, including protecting the skin from the sun. However, there is still doubt today whether photoprotection is a real phenomenom or whether it is simply tanning of the skin. Plants have self-protective mechanisms and produce secondary metabolites that can protect themselves from UV radiation. Yet, can phytochemical compounds protect human skin? This review discusses the paradoxical effect of chemical UV filters and the influence of phytochemicals in in vitro and in vivo tests of photoprotection.

Influence of grape seed oil on sun protection factor in sunscreen formulations: a study using Central Composite Design approach

“…Many studies have evaluated the use of natural products as aids in skin photoprotection. Chiari-Andreo et al (2020) (23) presented a review regarding the photoprotection properties of phytochemical and secondary metabolites from plants. They possess the ability to absorb UVA and UVB rays as well the chemical sunscreen compound, besides antioxidant and anti-inflammatory effects.…”

Natural photoprotectors: A literature review

“…Excessive exposure to solar radiation increases the risk of skin cancer (Chiari-Andréo et al, 2020). Therefore, awareness of skin cancer and other negative health effects, as well as preventive measures, has become a public health issue.…”