Estudo preliminar toxicológico, antibacteriano e fitoquímico do extrato etanólico das folhas de Jatropha mollissima (Pohl) Baill. (pinhão-bravo, Euphorbiaceae), coletada no Município de Tauá, Ceará, Nordeste Brasileiro

Braquehais, Isabel Desidério; Vasconcelos, Fábio Perdigão; Ribeiro, Ana Raquel Carneiro; Silva, A.R.A Da; Franca, Maria Gleiziane Araújo; Lima, Daniele Rodrigues de; Paiva, C. F. de; Guedes, Maria Izabel Florindo; Magalhães, Francisco Ernani Alves

doi:10.1590/1983-084x/15_164

Cited by 28 publications

(19 citation statements)

References 15 publications

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“…Our tests are still in their primary stage with regards to the production chain of raw materials which can be used in the phytotherapeutic drugs industry. Therefore, it is necessary to develop studies to verify the efficiency of different concentrations of methanolic extracts of L. ferrea fruits, in addition to toxicity tests on the extracts of mycorrhizal plants (Braquehais et al, 2016;Santos et al, 2017). Complementary studies should include assessing the synergic effect of extracts of mycorrhizal L. ferrea fruits with antibiotics.…”

Section: Resultsmentioning

confidence: 99%

Is AMF inoculation an alternative to maximize the in vitro antibacterial activity of Libidibia ferrea extracts?

Santos

Muniz

Barbosa

et al. 2021

RSD

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Arbuscular mycorrhizal fungi (AMF) are known to provide plant species with several benefits, such as an increased production of bioactive compounds. However, it is yet to be defined whether extracts of mycorrhizal plants are more efficient in vitro antibacterial actions when compared to non-mycorrhizal plants. We tested the hypothesis of whether or not, methanolic extracts of Libidibia ferrea fruits, from plants established in the field and inoculated with AMF, have higher antibacterial action when inoculated with Acaulospora longula, Claroideoglomus etunicatum or Gigaspora albida. In addition, native L. ferrea fruits collected from the Caatinga area were also tested. The extracts of L. ferrea fruits inoculated with A. longula had higher in vitro antibacterial action in relation to the extracts of fruits from non-inoculated plants (p <0.05) thus characterizing the first record of different antibacterial actions of plant extracts due to inoculation with AMF. The extracts of L. ferrea fruits inoculated with A. longula were more efficient in inhibiting growth of Gram-negative bacteria. The zone diameters of inhibition ranged from 2.48 % to 7.56 % larger than the zones of the non-inoculated L. ferrea fruit extracts. The inoculation of L. ferrea with AMF may represent an alternative way of producing fruits with different antibacterial activity.

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Section: Resultsmentioning

confidence: 99%

Is AMF inoculation an alternative to maximize the in vitro antibacterial activity of Libidibia ferrea extracts?

Santos

Muniz

Barbosa

et al. 2021

RSD

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“…The toxicity results of the BHESC and LHESP extracts are also valuable, since samples that are toxic to A. salina can contain bioactive compounds with antitumor, antimalarial, trypanosomicidal, and insecticidal potential [38], possible antiplasmodic activity [39], and antimicrobial effect [40]. …”

Section: Resultsmentioning

confidence: 99%

Bioactivity and Toxicity of Senna cana and Senna pendula Extracts

Monteiro

Júnior

Oliveira

et al. 2018

Biochemistry Research International

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This work investigated the content of total polyphenolic compounds and flavonoids as well as their toxicity and larvicidal and acetylcholinesterase inhibitory activities. The antioxidant activities of two medicinal Senna species extracts (Senna cana and Senna pendula) were also investigated. The ethanol extract of the leaves of S. cana and the ethanol extract of the branches of S. pendula presented the best performance in the DPPH/FRAP and ABTS/ORAC assays, respectively. For the inhibition of acetylcholinesterase, the hexane extract of the flowers of S. pendula presented the lowest IC50 value among the ethanol extracts of the leaves of S. cana and showed the best performance in some assays. The hexane extract of the leaves of S. pendula and the hexane extract of the branches of S. cana were moderate to Artemia salina Leach. In the quantification of phenols and flavonoids, the ethanol extract of the leaves of S. cana presented the best results. The ethanol extracts of the leaves of S. cana were found to be rich in antioxidants, phenolic compounds, and flavonoids. These results indicate the antioxidant potential of the extracts of Senna species and can be responsible for some of the therapeutic uses of these plants.

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“…Nesse sentido, os óleos essenciais produzidos pelas plantas protegem contra a herbivoria, patogênicos e intempéries ambientais (Da Silva et al, 2009;Braquehais et al, 2016;Naik, 2016), são considerados ainda uma fonte indispensável de novas moléculas candidatas a fármacos, na pesquisa de novos antimicrobianos, razão pela qual vêm se tornando cada vez mais objeto de estudo e pesquisa para obtenção de novas substâncias com atividade medicinal. (Groot & Schmidt, 2016;Siqueira et al, 2020).…”

Section: Introductionunclassified

Composição química e atividade antifúngica do óleo essencial de Zanthoxylum petiolare A. St. -Hil. & Tul (RUTACEAE) / Chemical composition and antifungal activity of the essential oil of Zanthoxylum petiolare A. St.-Hil. & Tul (RUTACEAE)

Filho¹,

Neves²,

Moraes³

et al. 2021

BJDV

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RESUMOO objetivo deste trabalho foi avaliar o perfil químico e a atividade antifúngica do óleo essencial das folhas da espécie Zanthoxylum petiolare A.St.-Hil. & Tul. (Rutaceae). Para isso foram realizados estudo fitoquímico e antifúngico. A extração do óleo foi realizada utilizando aparelho Clevenger e a composição química foi determinada por Cromatografia Gasosa acoplada a Espectrometria de Massas (CG-EM). Os testes de sensibilidade foram realizados por microdiluição em caldo em cepas de fungos dermatófitos e leveduriformes. A análise do óleo essencial identificou 20 compostos químicos, onde o espatulenol (19,85%), geranial (16,31%), cis-Citral (12,54%) foram compostos majoritário. O óleo essencial mostrou atividade antifúngica contra as cepas de Trichophytom rubrum, apresentando 0, 156 mg/ml e 0,312 mg/ml para CIM e CFM, respectivamente, não manifestando ação contra Candida spp. Este é o primeiro estudo a investigar a atividade antifúngica de Z. petiolare que se mostrou uma espécie promissora para estudos posteriores com o propósito de se identificar novos metabólitos com ações farmacológicas.

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Estudo preliminar toxicológico, antibacteriano e fitoquímico do extrato etanólico das folhas de Jatropha mollissima (Pohl) Baill. (pinhão-bravo, Euphorbiaceae), coletada no Município de Tauá, Ceará, Nordeste Brasileiro

Cited by 28 publications

References 15 publications

Is AMF inoculation an alternative to maximize the in vitro antibacterial activity of Libidibia ferrea extracts?

Is AMF inoculation an alternative to maximize the in vitro antibacterial activity of Libidibia ferrea extracts?

Bioactivity and Toxicity of Senna cana and Senna pendula Extracts

Composição química e atividade antifúngica do óleo essencial de Zanthoxylum petiolare A. St. -Hil. & Tul (RUTACEAE) / Chemical composition and antifungal activity of the essential oil of Zanthoxylum petiolare A. St.-Hil. & Tul (RUTACEAE)

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