Toxicidade reprodutiva do extrato hidroalcóolico de Samanea tubulosa Benth em ratas wistar

Sales, P. A. B.; Oliveira, Jamylla Mirck Guerra de; Moura, Emanuela Ribeiro; Sousa, Marina Rebeca Soares Carneiro de; Silva, I. R.; Costa, T. N. da; Costa, A. P. R.

doi:10.1590/1983-084x/13_092

Cited by 3 publications

(2 citation statements)

References 4 publications

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“…A dried plant specimen (4653) was deposited at the Herbarium of the Nucleus of Ecology and Environmental Monitoring (NEMA) of the Federal University of Vale do São Francisco (UNIVASF). In the Chemistry Laboratory of IF SERTÃO-PE -Campus Petrolina Zona Rural, the leaves were subjected to solvent extraction to obtain the crude ethanolic extract (CEE) according to the methodology described by Sales et al (2015). The ointment was prepared as follows: each 200 g (base) contained 5% of Jatobá extract, 100 drops of propylene glycol, and 45 drops of Tween.…”

Section: Introductionmentioning

confidence: 99%

Interference of natural extract from Jatobá (Hymenaea martiana Hayne) with the physico-chemical characteristics and yield of goat milk and cheese

Silva

Mesquita

Machado

et al. 2022

Arq. Bras. Med. Vet. Zootec.

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Several studies have assessed the therapeutic potential of natural products against mastitis, but only a few have evaluated the impacts of this alternative therapy on the main properties of milk and dairy products. In this study, we observed how the treatment of mastitis with ethanolic extract of Jatobá (Hymenaea martiana Hayne) influenced the physicochemical and sensory characteristics of coalho cheese. An ointment containing the ethanolic extract was prepared for intramammary use in six dairy goats. The experiment was conducted in three experimental moments. Milking was performed, manually, and both milk and cheese were subjected to physicochemical and sensory tests. No difference was observed (p>0.05) in the physicochemical aspects of milk between the studied groups. The solids-non-fat showed a statistical difference between experimental moments M1 and M2. The protein means varied from 3.33 to 3.62, and there was a statistical difference between the two moments, while the lactose means varied from 4.79 to 5.38%. The physicochemical aspects of cheese remained similar with both treatments. Except for appearance, the sensory characteristics showed no statistical difference. In conclusion, the use of Jatobá extract ointment did not influence the physicochemical and sensory characteristics of goat milk or cheese.

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Section: Introductionmentioning

confidence: 99%

Interference of natural extract from Jatobá (Hymenaea martiana Hayne) with the physico-chemical characteristics and yield of goat milk and cheese

Silva

Mesquita

Machado

et al. 2022

Arq. Bras. Med. Vet. Zootec.

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“…This study was conducted at the Federal University of Piauí. Ethanol extract of S. tubulosa administered on female Wistar rats was toxic to the fetus, causing malformations, fetal resorption and pronounced decrease in birth weight (Sales et al, 2011). Due to these results, we aimed to evaluate the toxicity in vitro and in vivo of ethanol extract (EESt) pods of S. tubulosa.…”

Section: Introductionmentioning

confidence: 99%

Acute oral toxicity and cytotoxicological evaluation of the ethanol extract of Samanea tubulosa pods in Swiss mice

Sales¹,

Nicolau²,

Oliveira³

et al. 2015

Afr. J. Biotechnol.

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Acute toxicity and cytotoxicity of ethanol extract of Samanea tubulosa (EESt) pods were evaluated in Swiss mice. Acute toxicity studies were conducted based on OECD guidelines 420, where the limit test dose was 5000 mg/kg. Observation was made and recorded systemically for 1, 2, 4 and 24 h after the administration of dose for skin changes, morbidity, aggression and sensitivity of the behavior of the animals. For the cytotoxicity, 3-[4,5-dimethylthiazol-zil] -2,5-diphenyltetrazolium (MTT) test and hemolysis were performed with concentrations of 6.25 to 800 µg/ml. No significant variation (p < 0.05) in the body and organ weights between the control and the treated group was observed after 14 days of treatment. Pathologically, neither gross abnormalities nor histopathological changes were observed. No mortality was recorded in 14 days. Moreover, both cytotoxic tests made no significant alterations to be able to display the evidence of the effect of cytotoxic. Therefore, we suggest that EESt use is safe in a systemic and cellular level.

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Endopleura uchi (Huber) Cuatrec.: A medicinal plant for gynecological treatments – A reproductive toxicity assessment in zebrafish (Danio rerio)

Hyacienth¹,

Sánchez-Ortíz²,

Picanço³

et al. 2020

Journal of Ethnopharmacology

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Toxicidade reprodutiva do extrato hidroalcóolico de Samanea tubulosa Benth em ratas wistar

Cited by 3 publications

References 4 publications

Interference of natural extract from Jatobá (Hymenaea martiana Hayne) with the physico-chemical characteristics and yield of goat milk and cheese

Interference of natural extract from Jatobá (Hymenaea martiana Hayne) with the physico-chemical characteristics and yield of goat milk and cheese

Acute oral toxicity and cytotoxicological evaluation of the ethanol extract of Samanea tubulosa pods in Swiss mice

Endopleura uchi (Huber) Cuatrec.: A medicinal plant for gynecological treatments – A reproductive toxicity assessment in zebrafish (Danio rerio)

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