Evidências de medidas de normalidade para a espessura do músculo masseter avaliadas com ultrassonografia: estudo de revisão

Oliveira, Jabson Herber Profiro de; Filho, Mário Genuíno Dourado; Melo, Thais Myriam Aragão; Lima, Niedje Siqueira de; Filho, Milton Marcelino; Silva, Hilton Justino da

doi:10.1590/1982-021620150514

Cited by 3 publications

(1 citation statement)

References 55 publications

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“…This measurement was repeated three times, and the average value was used in the analysis. 13,14 The evaluation of muscle thickness of both sides of each patient's masseter muscle was conducted by the same investigator as much as possible. Changes in the volume of the lower face were evaluated through 3D facial contouring using Morpheus 3D imaging, and patients were required to maintain within ±10% of their baseline weight during the study period.…”

Section: Assessmentmentioning

confidence: 99%

A Multicenter Phase II Study Evaluating the Safety and Efficacy of Botulax in Asian Patients with Benign Masseteric Hypertrophy

Son

Kim

Lee

2023

Plastic &Amp; Reconstructive Surgery

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Benign masseteric hypertrophy (BMH), which results in a strong, masculineappearing jaw, is common in the Asian population, and there is great interest in BMH treatment in Korea. 1 BMH arises from various etiologies, including temporomandibular joint disorders, bruxism, mental stress, and work hypertrophy from chewing. 2,3 To improve BMH, conservative or surgical treatments have been attempted as treatment options. 4,5 There have been many studies on BMH treatment using botulinum toxin A (BTA), a 150-kD polypeptide consisting of a light chain and a heavy chain linked by disulfide bonds. [6][7][8] Especially in the case of BMH caused by bruxism, botulinum toxin relieves the symptoms of bruxism and shrinks the enlarged masseter muscle. 9 Therefore, it is used as a treatment option because it can achieve the double effect of improving the jaw line cosmetically while improving the condition of the teeth. The botulinum toxin injection method has distinct advantages, Background: Benign masseteric hypertrophy (BMH) is a condition in which the thickness of the masseter muscle is increased, resulting in jawline prominence with an undesirable cosmetic appearance. Botulinum toxin type A (BTA) injection is a promising treatment option, but its effective dose remains debated. Methods: Adults older than 19 diagnosed with BMH through visual examination and palpation related to a masseter muscle prominence were selected, and 80 patients were randomly assigned into five groups (placebo group and four groups with different doses of BTA: 24 U, 48 U, 72 U, or 96 U, on both sides of the jaw) and treated with placebo or BTA once at their baseline visit. During each follow-up, the treatment efficacy was evaluated with ultrasound examination of the masseter muscle, three-dimensional facial contour analysis, visual evaluation by the investigator, and patient satisfaction evaluation. Results: The mean age of the 80 patients was 42.7 ± 9.98 years; 68.75% were women. The mean change in masseter muscle thickness during the maximum clenching state after 12 weeks of drug administration compared with baseline in the 24-U, 48-U, 72-U, and 96-U groups were −2.33 ± 0.41 mm, −3.35 ± 0.42 mm, −2.86 ± 0.42 mm, and −3.79 ± 0.42 mm, respectively. All treatment groups showed a statistically significant decrease compared with placebo. Regarding subjective satisfaction, all treatment groups, except the 24-U group at 4 weeks, showed higher satisfaction than the placebo group during all visits. No significant adverse events were noted. Conclusion: BTA administration of at least 48 U for BMH is more cost-effective than high-dose units and has a low risk of side effects.

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Section: Assessmentmentioning

confidence: 99%

A Multicenter Phase II Study Evaluating the Safety and Efficacy of Botulax in Asian Patients with Benign Masseteric Hypertrophy

Son

Kim

Lee

2023

Plastic &Amp; Reconstructive Surgery

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USG Imaging in Orthodontics

Orhan

Görürgöz

2021

Ultrasonography in Dentomaxillofacial Diagnostics

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Relação da espessura e da atividade elétrica do músculo masseter com a força de mordida: um estudo morfológico e eletrofisiológico

et al. 2016

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RESUMO: Objetivo: estudar a relação da espessura e da atividade elétrica do músculo masseter com a força de mordida. Métodos: participaram do estudo 17 adultos jovens (21,3 ( 1,4 anos), sendo 7 do gênero feminino e 10 do gênero masculino, saudáveis e clinicamente assintomáticos, quanto a disfunções temporomandibulares. Foi efetuada a medida da espessura do músculo masseter unilateralmente, durante o repouso e contração voluntária máxima. Também foi quantificada a força de mordida para cada lado com um transdutor de força posicionado na região do primeiro molar e simultaneamente avaliou-se atividade elétrica do masseter durante a mordida unilateral. A análise foi baseada na comparação das amostras, sendo utilizados o test t, Wilcoxon, Mann-Whitney e regressão linear multivariada. Resultado: a espessura do músculo masseter foi maior nos homens, tanto no repouso quanto em contração. Observou-se uma simetria entre os lados com os músculos em repouso e em contração. A frequência mediana do sinal eletromiográfico, para o músculo masseter em contração voluntária máxima, não apresentou diferença estatisticamente significante intra-indivíduos e na comparação entre os gêneros. Foi encontrada maior força de mordida nos indivíduos do gênero masculino. Não foi encontrado um modelo de regressão linear multivariada entre as variáveis estudadas. Conclusão: neste estudo, não foi possível encontrar um modelo linear com as variáveis estudadas.

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Evidências de medidas de normalidade para a espessura do músculo masseter avaliadas com ultrassonografia: estudo de revisão

Cited by 3 publications

References 55 publications

A Multicenter Phase II Study Evaluating the Safety and Efficacy of Botulax in Asian Patients with Benign Masseteric Hypertrophy

A Multicenter Phase II Study Evaluating the Safety and Efficacy of Botulax in Asian Patients with Benign Masseteric Hypertrophy

USG Imaging in Orthodontics

Relação da espessura e da atividade elétrica do músculo masseter com a força de mordida: um estudo morfológico e eletrofisiológico

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