Impact of soy consumption on human health: integrative review

Nogueira‐de‐Almeida, Carlos Alberto; Ferraz, Ivan Savioli; Ued, Fábio da Veiga; Almeida, Ane Cristina Fayão; Ciampo, Luíz Antônio Del

doi:10.1590/1981-6723.12919

Cited by 10 publications

(4 citation statements)

References 94 publications

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“…The anticancer properties of puerarin, daidzein, genistein and formononetin, the main components of the studied isoflavone-rich NADES extract of Pueraria lobata roots, are widely known and have been extensively reviewed [ 6 , 17 , 18 , 19 , 20 , 21 ]. All four isoflavones have been reported to have anticancer activity.…”

Section: Discussionmentioning

confidence: 99%

Effects of Isoflavone-Rich NADES Extract of Pueraria lobata Roots and Astaxanthin-Rich Phaffia rhodozyma Extract on Prostate Carcinogenesis in Rats

Семенов

Tyndyk

Von

et al. 2023

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Prostate cancer (PCa) is one of the most common male malignancies worldwide. In the current study, we evaluated the effects of a natural deep eutectic solvent (NADES) extract of Pueraria lobata roots rich in isoflavones (ISF) and Phaffia rhodozyma extract rich in astaxanthin (ASX) on an N-methyl-N-nitrosourea plus testosterone PCa model in rats. ISF consisted of puerarin, daidzein, genistein, formononetin and other polyphenols, while ASX contained lipids and unsaturated species in addition to astaxanthin. Extracts were administered through a whole promotion period in daily doses shown by our group to successfully inhibit benign prostate hyperplasia (BPH) development — 200 mg/kg for ISF and 25 mg/kg for ASX. Though a similar effect was found for BPH processes accompanying PCa induction, the incidence of PCa in animals treated with placebo, ISF and ASX was 37%, 37% and 41%, respectively, showing no chemopreventive activity of ISF and ASX. PCa development was associated with a decrease in the Ca/Mg ratio in serum and an increase in prostate tissue. Treatment with both extracts produced a normalization effect on Ca balance in serum, which, combined with a decrease in the prostatic index, suggests some positive health effects of ISF and ASX.

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Section: Discussionmentioning

confidence: 99%

Effects of Isoflavone-Rich NADES Extract of Pueraria lobata Roots and Astaxanthin-Rich Phaffia rhodozyma Extract on Prostate Carcinogenesis in Rats

Семенов

Tyndyk

Von

et al. 2023

Plants

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“…A farinha de ervilha pelo aporte de proteínas e quantidades significativas de aminoácidos lisina e leucina (Ojeda, 2016). A farinha de soja devido ao aumento do teor de proteínas e pelas propriedades nutricionais e funcionais (Nogueira-de-Almeida et al 2020).…”

Section: Principais Características Das Farinhas E Dos Amidos Utiliza...unclassified

“…A soja e seus derivados são considerados alimento funcional, pela presença de compostos bioativos como as isoflavonas, representadas na forma de daidzeínas, genisteínas e a gliciteínas, as saponinas, os fitosteróis, os peptídeos com baixo peso molecular, os oligossacarídeos e os ácidos graxos poli-insaturados, que auxiliam na redução de riscos de doenças crônicas, tais como: doenças cardiovasculares, aterosclerose, câncer, osteoporose, doenças renais e manifestações da menopausa (Dalpizol et al, 2020;Nogueira-de-Almeida et al 2020;Frigo et al 2021).…”

Section: Farinha De Sojaunclassified

Substituintes da farinha de trigo na elaboração de produtos de panificação sem glúten - uma revisão

Moraes

Silva²

2023

RSD

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A farinha de trigo é o principal ingrediente utilizado na fabricação de produtos de panificação, devido à capacidade de formar uma rede viscoelástica, capaz de reter o gás durante a etapa de fermentação da massa. No entanto, existe uma demanda por produtos sem glúten para atender a populações que apresentam restrições de consumo alimentar, como alergias, intolerâncias ou sensibilidade aos componentes do trigo. Objetivou-se nesta revisão apresentar as principais matérias-primas que têm sido utilizadas como alternativas a farinha de trigo para a elaboração de produtos de panificação sem glúten. Desta forma, foi realizada uma pesquisa nas principais bases de dados, Google Acadêmico, SciElo, Scopus, PubMed, Lilacs, Web of Science, utilizando-se termos relacionados ao assunto como: intolerância ao glúten, celíaco, alergia ao trigo e farinhas sem glúten. Foram selecionados 53 estudos, publicados no período de 2012 a 2022. A partir deste levantamento observou-se que a maioria dos estudos são direcionados ao desenvolvimento de formulações de biscoitos e pães sem glúten. Os principais materiais utilizados foram as farinhas de arroz, ervilha, amaranto e soja, geralmente utilizadas em combinações, sendo estas dependentes da finalidade, como, por exemplo, conferir crocância (textura) em biscoitos ou maciez em pães e bolos. Além disso, observou-se que a escolha das matérias-primas considera também o balanço nutricional, pois na maioria dos estudos as formulações foram desenvolvidas utilizando-se combinações entre fontes proteicas, amiláceas e fibrosas.

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“…For centuries, Asians have consumed large amounts of isoflavone-rich soybeans and soy products [ 134 , 135 ]. That has changed significantly with the shift towards a “western” diet rich in energy and fat [ 129 , 136 ], yet they still consume more soy products than Westerners [ 137 ]; that is why the influence of major soy isoflavones on the risks of developing type 2 diabetes is being investigated.…”

Section: Genistein As a Biologically Active Plant Compoundmentioning

confidence: 99%

Genistein—Opportunities Related to an Interesting Molecule of Natural Origin

et al. 2022

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Nowadays, increasingly more attention is being paid to a holistic approach to health, in which diet contributes to disease prevention. There is growing interest in functional food that not only provides basic nutrition but has also been demonstrated to be an opportunity for the prevention of disorders. A promising functional food is soybean, which is the richest source of the isoflavone, genistein. Genistein may be useful in the prevention and treatment of such disorders as psoriasis, cataracts, cystic fibrosis, non-alcoholic fatty liver disease and type 2 diabetes. However, achievable concentrations of genistein in humans are low, and the use of soybean as a functional food is not devoid of concerns, which are related to genistein’s potential side effects resulting from its estrogenic and goitrogenic effects.

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Impact of soy consumption on human health: integrative review

Cited by 10 publications

References 94 publications

Effects of Isoflavone-Rich NADES Extract of Pueraria lobata Roots and Astaxanthin-Rich Phaffia rhodozyma Extract on Prostate Carcinogenesis in Rats

Effects of Isoflavone-Rich NADES Extract of Pueraria lobata Roots and Astaxanthin-Rich Phaffia rhodozyma Extract on Prostate Carcinogenesis in Rats

Substituintes da farinha de trigo na elaboração de produtos de panificação sem glúten - uma revisão

Genistein—Opportunities Related to an Interesting Molecule of Natural Origin

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