Age-related episodic memory decline and the role of amyloid-β: a systematic review

Souto, Jandirlly J. S.; Silva, Gabriella M.; Almeida, Natalia L.; Shoshina, I. I.; Santos, Natanael Antônio dos; Fernandes, Thiago P.

doi:10.1590/1980-57642021dn15-030002

Cited by 5 publications

(3 citation statements)

References 112 publications

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“…In a very recent study, it has been discussed that delayed recall as a way of assessing episodic memory impairment is one of the most significant predictive factors in defining the progression of Alzheimer’s disease [ 36 ]. Regarding the population of adults with vascular aging, research thus far shows findings that tend to be consistent with a decline of episodic memory as well [ 40 , 41 ].…”

Section: Introductionmentioning

confidence: 99%

Trajectories of Cognitive Impairment in Adults Bearing Vascular Risk Factors, with or without Diagnosis of Mild Cognitive Impairment: Findings from a Longitudinal Study Assessing Executive Functions, Memory, and Social Cognition

et al. 2022

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With the aging of the population, a key concern of both societies and health services is to keep the population cognitively healthy until the maximum age limit. It is a well-known fact that vascular aging has a negative effect on the cognitive skills of adults, putting them at greater risk of developing dementia. The present longitudinal study aimed to evaluate the main dimensions of cognition in two pathological groups with different health profiles: a group of adults with vascular risk factors (VRF) (n = 35) and a group of adults with vascular risk factors and mild cognitive impairment (VRF + MCI) (n = 35). The two groups were matched in age, education, and gender. They were assessed with extensive neuropsychological testing at three different times with a distance of about 8 months between them; the assessment regarded executive functions, memory capacity, and Theory of Mind abilities. The analyses carried out were (a) mixed-measures ANOVA, (b) repeated measures ANOVA, and (c) ANOVA. The findings showed that global cognitive status and short-term memory are the main cognitive abilities that decline in community dwelling people bearing VRF. Hence, this group of adults should be examined at least every 2 years for this decline. As regards people with both VRF and MCI, it seems that the assessment of Theory of Mind abilities can better capture their further impairment. Global cognitive status, task/rule switching function, and long-term memory (delayed verbal recall) were revealed as the abilities that clearly and steadily differentiate VRF people with and without MCI.

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Section: Introductionmentioning

confidence: 99%

Trajectories of Cognitive Impairment in Adults Bearing Vascular Risk Factors, with or without Diagnosis of Mild Cognitive Impairment: Findings from a Longitudinal Study Assessing Executive Functions, Memory, and Social Cognition

et al. 2022

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“…Memory is one of the most impacted cognitive functions during aging. Aging is accompanied by decline in processing speed, attention span, episodic recall ability and execution of different tasks [3][4][5] . Memory complaints in older individuals are more prevalent among women 6,7 .…”

Section: Introductionmentioning

confidence: 99%

What it is like to be an older person with memory complaints: the perception of women seen at a Physical Rehabilitation Center

Moretto

Favarin

Costanaro

et al. 2023

Rev. bras. geriatr. gerontol.

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Objective To understand what it is like to be an older person with memory complaints from the perspective of women seen at a Physical Rehabilitation Center. Method A qualitative exploratory descriptive study was conducted involving a population of older women aged >60 years who had impaired cognitive function, as measured by the Mini-Mental State Examination (MMSE), and subjective memory complaints was carried out. A questionnaire was applied to characterize the participants and an audio-recorded semi-structured interview based on a guiding question was conducted. The transcribed interviews were analyzed using Bardin's Content Analysis. Results The age of the 19 participants ranged from 62 to 84 years, with mean of 72.37 (±6.72) years. Reading and analysis of the discourse produced in response to the guiding question revealed two categories: (1) feelings the older women experienced due to memory complaints; (2) daily life situations affected by memory complaints. Conclusion Being an older woman with memory complaints was reported as challenging, promoting changes in daily life, impacting situations that used to be routine, and requiring readjustments both for the older individual with memory impairment and those around them.

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“…A memória é uma das funções cognitivas mais afetadas durante o envelhecimento. Pode-se observar diminuição da velocidade de processamento, da capacidade de atenção, da capacidade de recordação episódica e de execução de diferentes tarefas com o envelhecer [3][4][5] . Entre pessoas idosas, queixas de memória são mais frequentes entre mulheres 6,7 .…”

Section: Introductionunclassified

O que é ser uma pessoa idosa que apresenta queixas de memória: a percepção de mulheres atendidas em um Centro de Reabilitação Física

Moretto

Favarin

Costanaro

et al. 2023

Rev. bras. geriatr. gerontol.

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Resumo Objetivo Conhecer e compreender o que é ser uma pessoa idosa que apresenta queixas de memória, por meio do olhar de mulheres atendidas em um Centro de Reabilitação Física. Método Estudo descritivo exploratório de caráter qualitativo com população composta por idosas acima de 60 anos que apresentavam alteração da função cognitiva, verificada por meio do instrumento Miniexame do Estado Mental (MEEM) e queixas subjetivas de memória. Foi aplicado um questionário para a caracterização das participantes e realizada uma entrevista semiestruturada áudio gravada baseada em uma pergunta orientadora. As entrevistas transcritas na íntegra foram analisadas com a Análise do Conteúdo de Bardin. Resultados As 19 participantes apresentavam idade entre 62 e 84 anos, com média de 72,37 (±6,72) anos. Por meio da leitura das falas relacionadas as respostas da pergunta orientadora e análise, foi possível identificar duas categorias: (1) sentimentos que as idosas vivenciam devido a queixa de memória; (2) situações da vida diária que são afetadas pela queixa de memória. Conclusão Ser uma idosa que apresenta queixas de memória se mostra como algo difícil, promove diversas mudanças no cotidiano, altera situações que costumavam ser comuns, sendo necessárias readaptações tanto da idosa que sofre com a dificuldade de memória, quanto para os indivíduos que estão a sua volta.

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Age-related episodic memory decline and the role of amyloid-β: a systematic review

Cited by 5 publications

References 112 publications

Trajectories of Cognitive Impairment in Adults Bearing Vascular Risk Factors, with or without Diagnosis of Mild Cognitive Impairment: Findings from a Longitudinal Study Assessing Executive Functions, Memory, and Social Cognition

Trajectories of Cognitive Impairment in Adults Bearing Vascular Risk Factors, with or without Diagnosis of Mild Cognitive Impairment: Findings from a Longitudinal Study Assessing Executive Functions, Memory, and Social Cognition

What it is like to be an older person with memory complaints: the perception of women seen at a Physical Rehabilitation Center

O que é ser uma pessoa idosa que apresenta queixas de memória: a percepção de mulheres atendidas em um Centro de Reabilitação Física

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