Incidence trend of five main causes of cancer, in greater Cuiabá, Mato Grosso, Brazil, 2000 to 2016

Abstract

Objective: To analyze the incidence trend of the five main causes of cancer, according to sex and age, in Greater Cuiabá, in the state of Mato Grosso, from 2000 to 2016. Methods: Incidence information was obtained from the Population-Based Cancer Registry, referring to the municipalities Cuiabá and Várzea Grande (RCBP — Cuiabá). Crude incidence rates were calculated and the five main types of cancer were selected: for males, prostate (C61), lung (C33–34), colorectal (C18–21), stomach (C16) and oral cavity cancer (C00–10); and for females, breast (C50), cervix (C53), colorectal (C18–21), lung (C33–34) and thyroid gland cancer (C73). Age-adjusted rates were calculated by the direct method, using the world population as reference. Trends were estimated using the Joinpoint method and evaluated by Annual Percent Change (APC) and Average Annual Percent Change (AAPC). The Joinpoint Regression Program software, version 8.3.6.1, was used. Results: During the period, there was a decreasing trend of lung (AAPC=-2.2; 95%CI −4.0–-0.3) and stomach cancer (AAPC=-5.2; 95%CI −7.7–-2.6) in men, and of cervix cancer (AAPC=-7.2; 95%CI −9.0–-5.3) in women, and increasing for breast (AAPC=2.8; 95%CI 0.2–5.5) and thyroid cancer (AAPC=8.3; 95%CI 4.6–12.2). Conclusion: In Greater Cuiabá, we found a downward incidence trend among elderly men for prostate, lung and stomach cancer. Women are affected at younger age groups, with an upward trend for breast cancer and downward trend for cervix cancer.