Alginate/Bioactive Glass Beads: Synthesis, Morphological and Compositional Changes Caused by SBF Immersion Method

Abstract

Composites of biodegradable polymers/bioactive glasses (BG) are of particular interest in bone repair, where ceramic phase can improve osteogenic features. This work reports the development of organic-inorganic beads based on alginate prepared by incorporating at polymer suspension different contents (25, 50 and 75 wt% with respect to alginate) of BG present at precursor solution, whose system (SiO 2 -CaO-P 2 O 5 ) was obtained by hydrolysis of both tetraethoxysilane (TEOS) and triethylphosphate (TEP) alkoxides, molar ratio TEOS:TEP of 1:0.1317, and which calcium source came from the same cold CaCl 2 solution used to gelling the hybrids. Beads were synthesized by extruding mixtures, drop by drop, in CaCl 2 solution. Were also investigated the behavior resulting upon soaking of hybrids into SBF. Samples were characterized by SEM, ATR-FTIR, TGA and XRD analysis. Results indicated decrease in spheres size with increase of glass and presence even pos-immersion, of Si, Ca and P associated to BG phase.

Ag0–Ginger Nanocomposites Integrated into Natural Hydrogelated Matrices Used as Antimicrobial Delivery Systems Deposited on Cellulose Fabrics

“…The FTIR-ATR spectrum of alginate has a wide band at about 3200 cm −1 , which was attributed to the overlapping of O-H stretching vibrations due to the strong intramolecular and intermolecular hydrogen bonds. The two bands at 1600 and 1410 cm −1 , respectively, correspond to the asymmetrical and symmetrical stretching vibrations of carboxylic ion [41]. The involvement of carboxylic groups in the process of hydration of the alginate matrix is confirmed in the G2 spectrum by the decrease in the intensity of the two characteristic bands.…”

“…In the case of the cellulose supports covered with natural hydrogel, in the FTIR analysis of each sample analyzed, the presence of polysaccharides will lead to the broadening of the characteristic O-H stretching bands around 3300 and 2900 cm −1 , which correspond to C-H stretching vibrations. At the same time, the hydroxyl [40], carboxylic [41], or methylene [26,42] functional groups grafted on the glycoside residues and the auxiliary compounds that are found in the biopolymer component presented characteristic bands of the coating types. Starch is one of the major constituents of rice flour.…”

A 3D Printing Scaffold Using Alginate/Hydroxyapatite for Application in Bone Regeneration

“…These characteristics make them important and promising biomaterials for various applications, including tissue engineering and drug-release devices. Among the several materials used to manufacture scaffolds, natural polymers are the options that most attract research due to their similarities with the extracellular matrix of the tissue, biological performance, and cellular interactions [10][11][12] .…”