I am deeply thankful to my family, Tânia, José, Tatiana and Bruno, for their love and encouragement during this process. I am also extremely grateful to Rayane, my love, for being part of my life, whose affection and solid companionship were decisive for the development of this work. Furthermore, I thank my friends and colleagues Thiago Peixoto, Francisco José and Maria Clara and Lucas Araujo for all the time we have been working together and for your always valuable contributions. This gratitude is extended to all my colleagues at University of Brasília, for providing me the opportunity of conducting a large set of experiments in their lab, as well as to everyone who has been there for me emotionally and intellectually throughout this journey.