Strategies to prevent HIV transmission to serodiscordant couples

Abstract

The articles recovered exhibit four main strategies: (1) condom; (2) reduction of risks in sexual practices; (3) use of antiretrovirals, particularly early initiation of antiretroviral therapy (TASP) and pre-exposure prophylaxis (PrEP); (4) risk reduction in reproduction. Discussion: TASP is highly effective in reducing sexual transmission, PrEP was tested in serodiscordant couples and both reduce the sexual transmission risk in different sexual practices, enabling individualized prevention strategies. Conclusions: When used in combination, antiretrovirals and sexual practices with condoms offer greater efficacy than any single strategy. The combined use of new and old strategies allows us to build a prevention policy for all.

An Event-Level Analysis of the Interpersonal Factors Associated With Condomless Anal Sex Among Gay, Bisexual, and Other Men Who Have Sex With Men (MSM) With Online-Met Partners

“…Alternatively, these finding may also be the result of small counts, as only 60 out of 995 baseline events among HIV-negative/unknown men were with partners whom the respondents knew or believed were HIV-positive. It is also possible that these relatively few instances of serodiscordant CAS may represent encounters between individuals who, for various reasons, are less concerned about the risks for HIV acquisition during CAS (Hallal et al, 2015; Stolte, Dukers, Geskus, Coutinho, & de Wit, 2004). …”

Achieving 90-90-90: A Focus on Sero-Discordant Couples

“…The findings of the study showed that there was substantial (92.0%) reduction of HIV risk transmission through the utilisation of HAART [27]. An emerging trend is to employ strategies in combination with ART to expand the possibilities of interventions for sero-discordant couples [26]. In a rural setting in KwaZulu-Natal, South Africa, Oldenburg et al [28] estimated the effect of ART in reducing the acquisition of HIV in sero-discordant couples in a HIV-hyperendemic and resource constrained setting.…”

“…They established that ART initiation was the most protective strategy employed. To demonstrate the effectiveness of the use of ARVs in reducing the risk of HIV transmission Hallal et al [26] cites the Partners in Prevention project, among various other studies in their systemic review. The study was conducted across seven African countries namely Botswana, Kenya, Rwanda, South Africa, Tanzania, Uganda, and Zambia.…”

Representações sociais do VIH/SIDA para adolescentes: Uma abordagem estrutural

“…Apesar do núcleo central denotar conhecimento científico sobre a doença, nota-se em seu sistema periférico um conhecimento mais embasado no senso comum, caracterizado pelo pensamento do surgimento da doença, ou seja, assim que a epidemia começou a emergir, e a histeria coletiva ocasionada pela mídia (Labra, 2013) acerca da doença pairava sobre sua fatalidade, mostrando uma forte ligação com a morte (Trigueiro et al, 2016). Contudo, ressalta-se sobre a mudança desse paradigma, visto que os escolares têm conhecimento de que esta pode ser prevenida, e que pode ser tratada, reduzindo a proliferação do vírus (Gaymard & Cazenave, 2018) e sua transmissão (Hallal, Raxach, Barcellos, & Maksud, 2015) e podendo prolongar a vida das PVH (Angelim et al, 2017).…”

“…O desenvolvimento de medicamentos antirretrovirais representou um marco para a década de 90 no que diz respeito ao VIH/SIDA, haja visto que tornou-se possível conviver com o vírus por mais tempo antes de desenvolver a síndrome (Labra, 2013). O que representa um marco no tratamento da doença, visto que a terapia ARV proporciona uma supressão na replicação viral (Hallal et al, 2015), reduzindo sua transmissibilidade, aumentando a expectativa de vida das PVH (Medeiros et al, 2016) e reduzindo a morbidade e mortalidade (Kuchenbecker, 2015;Medeiros et al, 2016).…”