Contribution to the study of Himatanthus sucuuba: latex macromolecule, microelements and carbohydrates

Silva, Jefferson Rocha de Andrade; Amaral, Ana Cláudia F.; Siani, Antônio Carlos; Rezende, Cláudia M.; Felcman, Judith; Pinto, Ângelo C.

doi:10.1590/1809-4392200331110

Cited by 10 publications

(2 citation statements)

References 17 publications

(12 reference statements)

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“…O látex dessa planta apresenta alguns compostos, como iridóides (plumieride, isoplumieride) (BARRETO et al, 2007), terpenos (acetato de lupeol, α-amirina) (de MIRANDA et al, 2000), miscelaneous (cis-poliisoprene, arabinose, glicose, xilose) (SILVA et al, 2003) e compostos fenólicos (catecol, quercitrin) que apresentam propriedades biologicas interessantes como anti-inflamatória, anti-tumoral e analgésica (de MIRANDA et al, 2000).…”

Section: O Exigenteunclassified

Atividade Antifúngica De Extratos Orgânicos Do Isolado Juant028 No Controle De Fitopatógenos

Shiraishi¹,

Oliveira²,

Dekker³

et al. 2019

Impactos Das Tecnologias Nas Ciências Biológicas E Da Saúde 3

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Section: O Exigenteunclassified

Atividade Antifúngica De Extratos Orgânicos Do Isolado Juant028 No Controle De Fitopatógenos

Shiraishi¹,

Oliveira²,

Dekker³

et al. 2019

Impactos Das Tecnologias Nas Ciências Biológicas E Da Saúde 3

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“…O pH ácido para a suspensão aquosa 1:4 (v/v) de látex de janaguba foi também observado para o látex bruto de H. succuba, porém com valor distinto, 4,54 (Silva et al, 2003). Para o látex bruto de mangabeira, Pinheiro et al (2004) Comportamento contrário ocorreu com as amostras D, E, I e J, cujo sedimento aumentou em 24 horas e com valores distintos entre si (Tabela 6).…”

Section: Determinação De Ph Densidade E Resíduo Secounclassified

Avaliação da qualidade de amostras comerciais de leite de janaguba (Himatanthus drasticus (Mart.) Plumel) em Fortaleza – Ceará

Soares

Almeida

Miranda

et al. 2016

Rev. bras. plantas med.

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RESUMO:Os fitoterápicos à base de leite de janaguba (Himatanthus drasticus (Mart.) Plumel), usados para o tratamento de câncer, úlcera gástrica e outras doenças, são muito vendidos em mercados públicos de Fortaleza (CE). No entanto, registros mencionam que é comum a troca deste leite por látex de mangabeira (Hancornia speciosa Gomes). O trabalho objetivou avaliar a qualidade físico-química, química e microbiológica de amostras comerciais do leite de janaguba. Dez amostras comerciais foram adquiridas de um mercado de Fortaleza; quatro amostras autênticas de látex de janaguba foram obtidas da chapada do Araripe e uma amostra de látex de mangabeira foi obtida em Paracuru (CE). Foram determinados o aspecto geral, densidade, pH, resíduo seco, volume de sedimentação, perfil cromatográfico e qualidade microbiológica das amostras. Os resultados mostraram elevada contaminação microbiológica nas preparações comerciais e adulteração em seis destas amostras, o que aponta a urgente implantação de uma efetiva farmacovigilância dos fitoterápicos a fim de tornar seu consumo mais seguro e racional.Palavras-chave: fitoterápicos, qualidade, látex; janaguba; Himatanthus drasticus ABSTRACT: Quality assessment of commercial samples of janaguba's milk (Himatanthus drasticus (Mart.) Plumel) in Fortaleza -Ceará. The herbal medicines made from janaguba milk (Himatanthus drasticus (Mart.) Plumel), used to treat gastric ulcer, cancer and other diseases, and arewidely sold in the public markets of Fortaleza (CE). However, records mention that it is common to make fake copies of the milk by using mango tree latex (Hanconia speciosa Gomes). This study aimed to evaluate the chemical, physical-chemical and microbiological quality of commercial samples of janaguba milk. Ten commercial samples were purchased from a Fortaleza market; four authentic samples of janaguba latex were obtained from the Araripe plateau, and one mango tree latex sample was obtained in Paracuru (CE). We determined the general appearance, density, pH, dry residue, sedimentation volume, chromatographic profile and microbiological qualities. Results showed high microbiological contamination in the commercial preparations and evidence of tampering in six of these samples, which indicates the need for an urgent implementation of an effective pharmacovigilance strategy for herbal medicines in order to make its consumption more secure and rational.

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Effect of Himatanthus sucuuba in Maternal Reproductive Outcome and Fetal Anomaly Frequency in Rats

Soares

Damasceno

Kempinas

et al. 2015

Birth Defects Research Pt B

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The aim of this study was to evaluate the effect of Himatanthus sucuuba on the maternal reproductive outcome and fetal anomaly incidence in rats. Pregnant rats were randomly divided into three experimental groups as follows: Control = treated with water (vehicle), treated 250 = treated with H. sucuuba at dose 250 mg/kg, and treated 500 = treated with H. sucuuba at dose 500 mg/kg. The rats were orally treated, by gavage, with H. sucuuba or vehicle (water) during preimplantation and organogenic period (from gestational day 0-14). At day 21 of pregnancy, all rats were killed to obtain maternal-fetal data. The treatment with H. sucuuba at dose of 250 mg/kg caused reduction in placental efficiency and an increase preimplantation loss rate and placenta weight compared with the control. The treated 500 group presented a significant decrease in maternal weight gain, maternal weight gain minus gravid uterus weight, fetal weight, and placental efficiency compared with the control. In this group, there was a decrease in body weight at day 20 of pregnancy and metacarpus ossification and an increase in the preimplantation loss rate and skeletal anomalies compared with other groups. Himatanthus sucuuba extract caused intrauterine growth restriction, preimplantation loss, and developmental delay in the high doses tested.

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Contribution to the study of Himatanthus sucuuba: latex macromolecule, microelements and carbohydrates

Cited by 10 publications

References 17 publications

Atividade Antifúngica De Extratos Orgânicos Do Isolado Juant028 No Controle De Fitopatógenos

Atividade Antifúngica De Extratos Orgânicos Do Isolado Juant028 No Controle De Fitopatógenos

Avaliação da qualidade de amostras comerciais de leite de janaguba (Himatanthus drasticus (Mart.) Plumel) em Fortaleza – Ceará

Effect of Himatanthus sucuuba in Maternal Reproductive Outcome and Fetal Anomaly Frequency in Rats

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