Effectiveness of nano-calcium phosphate paste on sensitivity during and after bleaching: a randomized clinical trial

Abstract

Abstract:The study aimed to evaluate the effectiveness of in-office bleaching and associated tooth sensitivity on application of nano-calcium phosphate paste as desensitizing agent. Bleaching was performed with 35% hydrogen peroxide gel in 40 patients who were randomly divided into placebo and nano-calcium phosphate paste groups. Bleaching efficacy (BE) was evaluated using a value-oriented Vita shade guide. Tooth sensitivity was recorded using a numeric rating scale (0-4) during bleaching and up to 48 h after each session. The primary outcome of absolute risk of tooth sensitivity was compared using the Fisher's exact test (α = 0.05). The intensity of tooth sensitivity and the efficacy of in-office bleaching were also statistically evaluated. No significant differences in absolute risk and intensity of tooth sensitivity were detected between the groups (p = 1.0 and p = 0.53, respectively). BE was also found to be similar between the groups (p = 0.67). Although the use of a nano-calcium phosphate paste associated with fluoride and potassium nitrate did not influence the whitening outcome, but it also did not reduce bleaching-induced tooth sensitivity.

Effect of application of desensitizers before bleaching on change of tooth shade

“…Moreover, another precursor of calcium phosphate (amorphous calcium phosphate) did not influence the tooth bleaching efficacy of tray-based bleaching gel while reducing sensitivity 8) . Use of desensitizing pastes containing nanocalcium phosphates prior to in-office bleaching did not influence the tooth bleaching effect 38) . However, it did not reduce tooth sensitivity induced by tooth bleaching in a randomized clinical trial 38) .…”

“…Use of desensitizing pastes containing nanocalcium phosphates prior to in-office bleaching did not influence the tooth bleaching effect 38) . However, it did not reduce tooth sensitivity induced by tooth bleaching in a randomized clinical trial 38) . With regard to color change, the results of this study indicate that the preliminary application of TM did not jeopardize the tooth bleaching effect of bleaching agent tested in this study.…”

Effect of high concentrated fluoride-based dentifrice on the hardness, roughness, and color of the bleached enamel

“…The repair of microscopic defects reduces hydrogen peroxide diffusion into the pulp chamber, which should theoretically minimize tooth sensitivity. [ 7 ] An ideal remineralizing system should provide calcium, phosphate, and fluoride ions that should be capable of affecting the subsurface in addition to forming deposits on the superficial layer of enamel. [ 8 ] Previous studies have used products based on different bioactive agents.…”

Enhanced bleaching effect of bovine tooth by hydrogen peroxide via calcium phosphate spheres

“…Our studies are based on natural bone micro materials-calcium phosphate (7)(8)(9)(10)(11)(12). This study aims to develop a method to reduce the potential damage of tooth caused by peroxide bleaching.…”