Efficacy of stannous, fluoride and their their combination in dentin erosion prevention in vitro

Abstract

The aim of this study was to compare the protective effects of solutions containing stannous (Sn), fluoride (F) and their combination in the prevention of dentin erosion. Forty bovine root dentin specimens (4'4'2 mm 3 ) were prepared and randomly assigned to 4 groups (n = 10): SnCl 2 (800 ppm/6.7 mM Sn), NaF (250 ppm/13 mM F), NaF/SnCl 2 (800 ppm/6.7 mM Sn; 250 ppm/13 mM F), and deionized water (DIW) as a negative control. An acquired pellicle was formed on dentin samples by incubation in clarified, pooled, stimulated human saliva for 24 hours. The specimens were subjected to 5 daily cycles, each consisting of 5 of min demineralization (0.3%/15.6 mM citric acid, pH 2.6, 6' /day) and 60 min of re-mineralization in clarified human saliva. Thirty minutes after the 1 st , 3 rd and 5 th demineralization episodes of each day, the specimens were treated with one of the test solutions for 2 min. Surface loss was measured via optical profilometry. Mixedmodel ANOVA followed by Tukey's test were used for the statistical analysis. Sn, F, and their combination significantly reduced the dentin surface loss by 23%, 36%, and 60% compared with DIW, respectively. All groups were significantly different (p < 0.05). The combination of Sn and F significantly reduced the amount of dentin surface loss compared with all other groups. The F group also significantly reduced surface loss compared with Sn and DIW, followed by the Sn group, which showed significantly greater protection compared with the DIW control. The daily use of a combined fluoride and stannous solution is promising for preventing dentin erosion.

Anti-Erosive Effect of Solutions Containing Sodium Fluoride, Stannous Chloride, and Selected Film-Forming Polymers

“…Many studies have shown the improved protection of solutions containing the combination F -+Sn 2+ in comparison with F -for preventing erosion [Schlueter et al, 2009a;Ganss et al, 2010a;Algarni et al, 2015aAlgarni et al, , 2015bScaramucci et al, 2015Scaramucci et al, , 2016. Nevertheless, in the present study, this effect was not so impressive.…”

Water sorption and solubility of a nanofilled composite resin protected against erosive challenges

“…Studies demonstrated satisfactory action of NaF based vehicles in the prevention of dental erosion in vitro. [25,26] On the teeth, NaF added to the calcium from the saliva leads to the formation of calcium fluoride, which generates a protective barrier, reducing the acid contact with the dental structure. [25,26] However, it was not possible to define whether the fluoride protection layer could also be formed on composite resin surfaces.…”

“…[25,26] On the teeth, NaF added to the calcium from the saliva leads to the formation of calcium fluoride, which generates a protective barrier, reducing the acid contact with the dental structure. [25,26] However, it was not possible to define whether the fluoride protection layer could also be formed on composite resin surfaces. [27] In addition, fluoride has a short life in the oral environment, as it is easily removed through the action of cheeks, tongue, saliva, chewing and by the usual oral hygiene procedures.…”

Can surface protection prevent the loss of hardness on dentin and composite resin surfaces exposed to erosive challenges?

“…stated that in conditions that simulate the frequency of daily acid exposure, routine mouth rinsing using solutions that contain NaF (250ppm F) significantly reduced the amount of the loss of dentine surface as compared with tin (Sn) and the control group.But Sundaram et al,23 found that fluoride applications did not reduce the amount of wear in comparison with the erosion control group. It could be postulated that the inability of fluoride to protect dentine surfaces against 18 DES-RE cycles is again related to its low capacity to stay on the surface and the fact that it is easily dissolved.Dentine sealants or desensitizing agents have been suggested to protect and seal exposed areas of the dentine 23. According to the authors, this noninvasive technique can be beneficial in the initial phases of the loss of hard tissue by delaying the wear and possibly lengthening the longevity of teeth.An important finding of this study was that the dentine hardness in groups protected with resinmodified glass ionomer varnish remained unaltered, even after 18 DES-RE cycles.…”