Endocannabinoid system and periodontitis: mechanisms and therapeutic implications
Lélio Fernando Ferreira SOARES,
Luan Viana FARIA,
Joni Augusto CIRELLI
Abstract:Introduction Periodontitis is a major public health problem. Although the principle of periodontitis therapy is mainly focused on removing dental biofilm and associated factors, its physiopathology enrolls different molecular and inflammatory events related to the host immune system, as the participation of the endocannabinoid system. Objective This review aimed to explore and elucidate the mechanisms and roles of the endocannabinoid system on periodontitis physiopathology and its possibilities for future rel… Show more
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