The effectiveness of percutaneous injections of ozonotherapy in low back pain

Abstract

SUMMARY INTRODUCTION Lumbar pain is one of the main reasons for medical consultation, causing the disruption of daily routines due to its disabling nature, thus resulting in social and personal damage. Among the complementary treatments, ozonotherapy offers analgesia to most patients, with reports of complications. However, great questions about its clinical effectiveness have not been answered yet, and there have been reports of serious complications. OBJECTIVE To describe the use of ozonotherapy in the treatment of lumbar pain, focusing on its favorable and unfavorable effects, and its analog profile. METHODS A cross-sectional bibliographic research was performed with scientific articles obtained from the Pubmed, LILACS and Scopus database, using the following descriptors: “Ozone”, “Therapy”, “Lumbar pain”, “complication”, “Disk herniation”, “Guideline”, “Protocol”, “Standards”, “Criteria”. RESULTS The researched literature corroborates that, in clinical practice, there is safety in the use of oxygen-ozone therapy through percutaneous injections for the treatment of lumbar pain, especially when compared to surgeries and use of medicines, provided that strict criteria are followed. CONCLUSION The procedure is effective and has a favorable analgesic profile. However, it is necessary to produce a medical guideline that will help in its strict and systematic control.

Ozone Preconditioning: Waking up the dragon

“…An increasing number of reports document the effectiveness of ozone PC for pain relief in a variety of chronic conditions including low back pain related to disc herniation, degenerative disc disease, sciatica, failed back surgery, as well as post-traumatic, inflammatory, and degenerative joint pain [19-28] [349][350][351][352][353][354][355][356][357][358][359][360][361][362][363][364][365][366]. In such cases ozone has been injected directly into the disc space, neural foramen or joint capsule.…”

Oxygen-Ozone Therapy for Reducing Pro-Inflammatory Cytokines Serum Levels in Musculoskeletal and Temporomandibular Disorders: A Comprehensive Review

“…Among these, O 2 O 3 represents a promising treatment option for its ability to modulate inflammation, promote cartilage growth, and joint repair mechanisms [ 48 , 61 , 98 ]. O 3 might influence the modulation of inflammation through different mediators and signaling pathways [ 4 , 99 , 100 ]. In synovial fluid, O 3 decreases the production of pro-inflammatory cytokines, particularly IL-6, IL-1β, and TNF-α, which are responsible for cartilage degradation [ 101 ].…”

Vias de aplicação da ozonioterapia no alívio da dor musculoesquelética: revisão integrativa / Pathways of application of ozone therapy in musculoskeletal pain relief: integrative review

“…O uso da ozonioterapia está baseado na exploração das propriedades químicas do ozônio, permitindo seus efeitos diretos (mecânicos) e indiretos (antiinflamatórios), deflagrando uma hiperoxigenação dos tecidos, diminuição dos componentes inflamatórios e regressão da dor (AZOLIN;BERTOL, 2018;BARBOSA, et al, 2020).…”

“…Nos estudos que utilizaram as variações da via paravertebral de oxigênio-ozônio, foi demonstrado uma maior segurança e facilidade de administração, por não ser necessário o uso de anestésicos, sedação e radiologia (BARBOSA et al, 2020;RODRIGUEZ et al, 2019;BIAZZO;CORRIERO;CONFALONIERI, 2018;SUCUOĞLU;SOYDAŞ, 2021;UCAR et al, 2020).…”

“…Brazilian Journal of Development,Curitiba, v.7, n.12, p. 112811-112824 dec. 2021 Outras vias foram encontradas com menor prevalência, a exemplo da aplicação de oxigênio-ozônio por epiduroscopia, por via intraforaminal e por via percutânea; todas de execução complexa, exigindo médicos treinados e experientes para realizar o procedimento(BARBOSA et al, 2020), não sendo factíveis para outros profissionais da saúde em suas práticas clínicas. Dias e colaboradores (2021) destacam que é válido e A falta de padronização das intervenções da ozonioterapia para alívio da dor musculoesquelética, não se limitou às vias de aplicação.…”