Intensity-modulated radiation therapy (IMRT) versus 3-dimensional conformal radiation therapy (3D-CRT) for head and neck cancer: cost-effectiveness analysis

Abstract

IMRT was considered cost-effective from the perspective of the Brazilian public health system.

Regional collaboration to improve quality of radiation therapy in Asia

“…Multiple systematic reviews and meta‐analyses conducted for various kinds of cancers have shown that IMRT is associated with greater tumour response and reduced side effects compared to 3DCRT 10–13 . This improved therapeutic ratio can lead to IMRT being more cost‐effective compared to 3DCRT, despite the higher upfront cost of IMRT 14 . Currently, many FARO countries still rely on 60 Co teletherapy machines rather than linear accelerators.…”

“…[10][11][12][13] This improved therapeutic ratio can lead to IMRT being more cost-effective compared to 3DCRT, despite the higher upfront cost of IMRT. 14 Currently, many FARO countries still rely on 60 Co teletherapy machines rather than linear accelerators. For example, Indonesia recently reported that up to 40% of all their teletherapy machines were 60 Co units.…”

The challenge of sustainability in healthcare systems: cost of radiotherapy in the last month of life in an Italian cancer center

“…There is still very little information in the literature on the use and cost of RT at the EOL, many of the studies not focusing on this specific RT setting [17][18][19], some limited to the analysis of a specific cancer site [14,[20][21][22][23] and others dealing with a specific RT technique [23][24][25][26][27]. There is also a paucity of methodological detail in published studies, along with considerable variation in the calculated cost estimates.…”

Aplicação tópica de creme contendo nanopartículas com vitamina E para prevenção de radiodermatite em mulheres com câncer de mama: estudo piloto randomizado

“…Os fatores relacionados ao tratamento incluem: a dose administrada em cada sessão, a dose total administrada, o volume de tecido tratado, o tipo de radiação utilizada, uso de bolus e a concomitância com quimioterapia (Censabella et al, 2017;DeHaven, 2014;Feight et al, 2011;Fernandez-Castro, Martin-Gil, 2015;Glover e Harmer, 2014;Harper et al, 2004;Kole, Kole, Moran, 2017;Leventhal, Young, 2017;McQuestion, 2011;Meghrajani et al, 2013;Pires, Segreto, Segreto, 2008;Ratosa, Jenko, Oblak, 2018;Salvo et al, 2010;Seité, Bensadoun, Mazer, 2017;Singh et al, 2016;Waghmare, 2013;Warnock, Lee, 2014). Técnicas modernas de teleterapia, como a IMRT (Intensity-modulated radiation therapy), mostram-se superiores no que concerne à incidência das reações de toxicidade da pele quando comparadas à terapia de radiação convencional (Feight et al, 2011;Fernandez-Castro, Martin-Gil, 2015;Leventhal, Young, 2017;Marta, Weltman e Ferrigno, 2018;McQuestion, 2011;Murray, Robinson, 2011;Pignol, Olivotto, Rakovitch, 2008;Ryan, 2012;Singh et al, 2016;Skliarenko, Warde, 2011;Teh, Woo, Butler, 1999;Waghmare, 2013;Warnock, Lee, 2014), porém o uso dessa tecnologia na prática diária não é considerado como tratamento padrão para pacientes com câncer de mama (Feight et al, 2011 Glover e Harmer, Harper et al, 2004;Kole, Kole, Moran, 2017;Leventh...…”

“…Os avanços e o desenvolvimento da tecnologia na área da radioterapia para o tratamento do câncer têm sido expressivos nos últimos anos. Tal fato tem possibilitado a aplicação de técnicas cada vez mais precisas, permitindo que a radiação ionizante apresente maior poder de penetração e que os feixes de radiação emitidos concentrem-se mais no tumor, permitindo maior preservação dos tecidos saudáveis adjacentes (Blecha, Guedes, 2006;Harper et al, 2004;Kole, Kole, Moran, 2017;Marta, Weltman e Ferrigno, 2018;Seité, Bensadoun, Mazer, 2017). Apesar desses progressos, os efeitos adversos advindos da radioterapia ainda são frequentes, pois a radiação ionizante causa danos em todas as células vivas, normais e malignas (Kole, Kole, Moran, 2017;Leventhal, Young, 2017;McQuestion, 2011;Pignol, Olivotto, Rakovitch, 2008;Ryan, 2012;Salvo et al, 2010;Warnock, Lee, 2014).…”