Fulminant liver failure in a street runner: Effects of heat stroke

Castro, Renata Rodrigues Teixeira de; Filho, Rubens Costa; Nóbrega, Antônio Cláudio Lucas da

doi:10.1590/1806-9282.64.03.208

Cited by 7 publications

(1 citation statement)

References 12 publications

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“…Successful treatments with emergency liver transplantation [6][7][8][9][10][11][12][13][14][15], MARS [16], plasma exchange alone [17,18], and hemofiltration [19] as well as cold dialysis and hemofiltration [20] have been published. ere is growing evidence that conservative management seems to be sufficient for the management of most cases, and a delayed transplant strategy is reasonable [8,12,[21][22][23][24][25][26][27][28][29][30][31], with cases reporting successful transplant after delaying transplantation in favour of spontaneous recovery [8,12]. Most reported cases survived, but fatalities have been reported due to liver failure [8,[32][33][34] or transplant complications [35][36][37].…”

Section: Discussionmentioning

confidence: 99%

A Case of Exertional Heat Stroke Complicated by Hypoxic Hepatitis

Woitok

Bahmad

Lindner

2020

Case Reports in Emergency Medicine

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Background.Exertional heat stroke is a life-threatening condition often complicated by multiorgan failure. We hereby present a case of a 25-year-old male presenting with syncope after a 10 km run in 28°C outside temperature who developed acute liver failure. Case Presentation. Initial temperature was found to be 41.1°C, and cooling measures were rapidly applied. He suffered from acute renal failure and rhabdomyolysis and proceeded to acute liver failure (ASAT 6100 U/l and ALAT 6561 U/l) due to hypoxic hepatitis on day 3. He did not meet criteria for emergency liver transplantation and recovered on supportive care. Conclusions. Acute liver failure due to heat stroke is a life-threatening condition with often delayed onset, which nevertheless resolves on supportive care in the majority of cases; thus, a delayed referral to transplant seems to be reasonable.

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