Asthma and occupation: Diagnosis using serial peak flow measurements

Abstract

evidence collection MethodThis guideline followed the standard of a systematic review with evidence retrieval based on evidence-based medicine (EBM), so that clinical experience is integrated with the ability to critically analyze and apply scientific information rationally, thus improving the quality of medical care. We used the structured mode of formulating questions synthesized by the acronym PICO, where P stands for patients with occupational asthma, I for indicator i.e. serial peak flow measurement, and O stands for the outcome of diagnosis.By raising a relevant question related to the proposed topic, we identified, based on the structured question, the keywords that formed the basis of the search for evidence in the databases: Medline-Pubmed, Lilacs, Labordoc and Cochrane Library. The studies had their abstracts reviewed and after applying the eligibility criteria (inclusion and exclusion), 33 articles were selected in order to answer the clinical doubt (Annex I). clinical questionIs there repercussion on clinical outcomes when applying serial peak flow measurements to diagnose work-related asthma among workers with respiratory symptoms?

Praćenje vršnog ekspiratornog protoka u dijagnozi profesionalne astme

“…Profesionalna astma (eng. occupational asthma) opstruktivna je plućna bolest karakterizirana varijabilnim smetnjama u protoku zraka kroz dišne putove i bronhalnom hiperreaktivnošću povezanom s upalom dišnih putova, koja je dominantno uzrokovana udisanjem štetnih plinova, para, dimova ili prašina na određenom radnom mjestu, a ne astmogenim čimbenicima izvan radnog okoliša (1)(2)(3). Profesionalna astma uključuje nekoliko patofizioloških entiteta: alergijsku astmu (eng.…”