Positron emission tomography/magnetic resonance imaging (PET/MRI): An update and initial experience at HC-FMUSP

Queiroz, Marcelo A.; Barbosa, Felipe de Galiza; Buchpiguel, Carlos Alberto; Cerri, Giovanni Guido

doi:10.1590/1806-9282.64.01.71

Cited by 7 publications

(3 citation statements)

References 91 publications

(110 reference statements)

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“…Thus, the images obtained through PET are based on the in-vivo biodistribution of the radiotracer together with the simultaneous anatomical CT images [ 60 ]. The use of magnetic resonance imaging (MR) in combination with PET (PET/MR) can also significantly contribute to anatomical and functional assessments; however, this type of equipment is still extremely expensive and scarcely available [ 61 ].…”

Section: Role Of 18 F-fdg Pet/ct In the Diagnosis ...mentioning

confidence: 99%

Anthracycline cardiotoxicity: current methods of diagnosis and possible role of 18F-FDG PET/CT as a new biomarker

et al. 2023

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Despite advances in chemotherapy, the drugs used in cancer treatment remain rather harmful to the cardiovascular system, causing structural and functional cardiotoxic changes. Positron-emission tomography associated with computed tomography (PET/CT) has emerged like a promising technique in the early diagnosis of these adverse drug effects as the myocardial tissue uptake of fluorodeoxyglucose labeled with fluorine-18 (18F-FDG), a glucose analog, is increased after their use. Among these drugs, anthracyclines are the most frequently associated with cardiotoxicity because they promote heart damage through DNA breaks, and induction of an oxidative, proinflammatory, and toxic environment. This review aimed to present the scientific evidence available so far regarding the use of 18F-FDG PET/CT as an early biomarker of anthracycline-related cardiotoxicity. Thus, it discusses the physiological basis for its uptake, hypotheses to justify its increase in the myocardium affected by anthracyclines, importance of 18F-FDG PET/CT findings for cardio-oncology, and primary challenges of incorporating this technique in standard clinical oncology practice.

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Section: Role Of 18 F-fdg Pet/ct In the Diagnosis ...mentioning

confidence: 99%

Anthracycline cardiotoxicity: current methods of diagnosis and possible role of 18F-FDG PET/CT as a new biomarker

et al. 2023

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“…ECoG requires surgery to fit the electrodes onto the surface of the cortex, making it an invasive technique [40]. MEG [41,42], PET [43][44][45], and fMRI [46][47][48] require very expensive and cumbersome equipment and facilities. Careful development of a set of calibration samples and application of multivariate calibration techniques is essential for near-infrared spectroscopy analytic methods.…”

Section: Bci Systems Classificationmentioning

confidence: 99%

An Introductory Tutorial on Brain–Computer Interfaces and Their Applications

et al. 2021

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The prospect and potentiality of interfacing minds with machines has long captured human imagination. Recent advances in biomedical engineering, computer science, and neuroscience are making brain–computer interfaces a reality, paving the way to restoring and potentially augmenting human physical and mental capabilities. Applications of brain–computer interfaces are being explored in applications as diverse as security, lie detection, alertness monitoring, gaming, education, art, and human cognition augmentation. The present tutorial aims to survey the principal features and challenges of brain–computer interfaces (such as reliable acquisition of brain signals, filtering and processing of the acquired brainwaves, ethical and legal issues related to brain–computer interface (BCI), data privacy, and performance assessment) with special emphasis to biomedical engineering and automation engineering applications. The content of this paper is aimed at students, researchers, and practitioners to glimpse the multifaceted world of brain–computer interfacing.

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“…However, it must be pointed out that the physiological or mental state studied, respectively, by PET and MRI may differ in varying levels during the two separated imaging sessions. Since patient’s condition could change between the two sessions of scanning, the confidence of findings from two imaging modalities relating to each other will be questioned (Queiroz et al, 2018). Brain imaging was destined to be the first applications of hybrid (simultaneous) PET/MRI system, which lead to real multiparametric functional analysis by using the two powerful modalities.…”

Section: Introductionmentioning

confidence: 99%

MRI-Driven PET Image Optimization for Neurological Applications

Zhu

2019

Front. Neurosci.

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Positron emission tomography (PET) and magnetic resonance imaging (MRI) are established imaging modalities for the study of neurological disorders, such as epilepsy, dementia, psychiatric disorders and so on. Since these two available modalities vary in imaging principle and physical performance, each technique has its own advantages and disadvantages over the other. To acquire the mutual complementary information and reinforce each other, there is a need for the fusion of PET and MRI. This combined dual-modality (either sequential or simultaneous) could generate preferable soft tissue contrast of brain tissue, flexible acquisition parameters, and minimized exposure to radiation. The most unique superiority of PET/MRI is mainly manifested in MRI-based improvement for the inherent limitations of PET, such as motion artifacts, partial volume effect (PVE) and invasive procedure in quantitative analysis. Head motion during scanning significantly deteriorates the effective resolution of PET image, especially for the dynamic scan with lengthy time. Hybrid PET/MRI device can offer motion correction (MC) for PET data through MRI information acquired simultaneously. Regarding the PVE associated with limited spatial resolution, the process and reconstruction of PET data can be further optimized by using acquired MRI either sequentially or simultaneously. The quantitative analysis of dynamic PET data mainly relies upon an invasive arterial blood sampling procedure to acquire arterial input function (AIF). An image-derived input function (IDIF) method without the need of arterial cannulization, can serve as a potential alternative estimation of AIF. Compared with using PET data only, combining anatomical or functional information from MRI for improving the accuracy in IDIF approach has been demonstrated. Yet, due to the interference and inherent disparity between the two modalities, these methods for optimizing PET image based on MRI still have many technical challenges. This review discussed upon the most recent progress, current challenges and future directions of MRI-driven PET data optimization for neurological applications, with either sequential or simultaneous acquisition approach.

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Positron emission tomography/magnetic resonance imaging (PET/MRI): An update and initial experience at HC-FMUSP

Cited by 7 publications

References 91 publications

Anthracycline cardiotoxicity: current methods of diagnosis and possible role of 18F-FDG PET/CT as a new biomarker

Anthracycline cardiotoxicity: current methods of diagnosis and possible role of 18F-FDG PET/CT as a new biomarker

An Introductory Tutorial on Brain–Computer Interfaces and Their Applications

MRI-Driven PET Image Optimization for Neurological Applications

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