Environmental factors can influence dengue reported cases

Carneiro, Marco Antonio F; Alves, Beatriz da Costa Aguiar; Gehrke, Flávia de Sousa; Domingues, José Nuno; Sá, Nelson Leite; Paixão, Susana; Figueiredo, João Paulo; Ferreira, Ana; Almeida, Cleonice; Machi, Amaury; Savóia, Eriane Justo Luiz; Nascimento, Vânia Barbosa do; Fonseca, Fernando L. A.

doi:10.1590/1806-9282.63.11.957

Cited by 21 publications

(20 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…It has been known that PM can modulate the level of cytokines, upon its exposure to the humans airways ( Bengalli et al., 2013 ; Hirota et al., 2015 ; Tang et al., 2019 ). PM were also reported to be associated with the virus infections such as Respiratory Syncytial Virus (RSV) ( Karr et al., 2009 ; Vandini et al., 2013 ), Influenza virus, Dengue virus ( Carneiro et al., 2017 ), Measles virus ( Chen et al., 2017a ; Peng et al., 2020 ) and Rhinovirus ( Proud et al., 2012 ). PM concentration has been shown to be linked with the increased number of infection rates in most of the virus-related outbreaks in the past two decades caused by RNA viruses, such as Severe Acute Respiratory Syndrome (SARS) – CoV in 2003 ( Cui et al., 2003 ), Dengue outbreak ( Massad et al., 2010 ), Swine flu H1N1 (Influenza) pandemic in 2009 ( Morales et al., 2017 ), H5N2 Influenza outbreak in United States (US), ( Zhao et al., 2019 ), Measles outbreak in 2019 ( Peng et al., 2020 ) and the recent ongoing COVID-19 outbreak ( Conticini et al., 2020 ; Dutheil et al., 2020b ; Fattorini and Regoli, 2020 ; Sciomer et al., 2020 ; Setti et al., 2020a ; Zhu et al., 2020 ).…”

Section: Introductionmentioning

confidence: 99%

Particulate matter (PM10) enhances RNA virus infection through modulation of innate immune responses

Mishra

Krishnamoorthy

Gangamma

et al. 2020

Environmental Pollution

View full text Add to dashboard Cite

Sensing of pathogens by specialized receptors is the hallmark of the innate immunity. Innate immune response also mounts a defense response against various allergens and pollutants including particulate matter present in the atmosphere. Air pollution has been included as the top threat to global health declared by WHO which aims to cover more than three billion people against health emergencies from 2019 to 2023. Particulate matter (PM), one of the major components of air pollution, is a significant risk factor for many human diseases and its adverse effects include morbidity and premature deaths throughout the world. Several clinical and epidemiological studies have identified a key link between the PM existence and the prevalence of respiratory and inflammatory disorders. However, the underlying molecular mechanism is not well understood. Here, we investigated the influence of air pollutant, PM 10 (particles with aerodynamic diameter less than 10 μm) during RNA virus infections using Highly Pathogenic Avian Influenza (HPAI) – H5N1 virus. We thus characterized the transcriptomic profile of lung epithelial cell line, A549 treated with PM 10 prior to H5N1infection, which is known to cause severe lung damage and respiratory disease. We found that PM 10 enhances vulnerability (by cellular damage) and regulates virus infectivity to enhance overall pathogenic burden in the lung cells. Additionally, the transcriptomic profile highlights the connection of host factors related to various metabolic pathways and immune responses which were dysregulated during virus infection. Collectively, our findings suggest a strong link between the prevalence of respiratory illness and its association with the air quality.

show abstract

Section: Introductionmentioning

confidence: 99%

Particulate matter (PM10) enhances RNA virus infection through modulation of innate immune responses

Mishra

Krishnamoorthy

Gangamma

et al. 2020

Environmental Pollution

View full text Add to dashboard Cite

show abstract

“…This is supported by a study from Malaysia, wherein a moderate negative correlation was detected between trapped larvae counts and Air Pollution Index (API) with a one-week lag [47]. Another found particulate matter 10 microns or less (PM10) to have a statistically signi cant negative correlation with dengue cases [48]. On the other hand, a lack of association between dengue activity and haze was concluded by another study from Singapore, investigating dengue activity between 2001-2008 [49].…”

Section: Discussionmentioning

confidence: 69%

Weather Factors Associated with Reduced Risk of Dengue Transmission in an Urbanized Tropical City

Gui

Gwee

Koh

et al. 2021

Preprint

View full text Add to dashboard Cite

IntroductionThe association of weather factors on dengue transmission in an urbanized tropical environment remains inconclusive. This study aims to assess the impact of weather factors on dengue incidence in Singapore between 2012 and 2019.MethodsData on weather variables (daily temperature, air quality, rainfall & wind speed) and weekly dengue incidence rates were collected from 1 January 2012 to 25 August 2019. Statistically significant correlated variables identified from cross-correlation analysis using Pearson’s correlation were examined in univariate ARIMA model. Quasi-Poisson model with a distributed lag non-linear model (DLNM) was established to assess any non-linear association between climatic factors and dengue incidence. FindingsPoor air quality (PSI: 150) and high wind speeds (12 km/h) were associated with reduced risk of dengue transmission in an urbanized tropical environment. Only a limited temperature range (27-32 °C and 23-25 °C) promotes dengue transmission whereas extreme heat inhibited dengue incidence (27°C, Ref. 25.14 °C; RR: 0.74, 95% CI: 0.58, 0.93). Rainfall exerts positive and negative influence alternately on weekly dengue cases across lags but the influence was not robust in sensitivity analysis. Based on split-sample model validation, mean temperature was the best predictor of dengue in prediction part (MAE: 43.15, RMSE: 51.39).

show abstract

“…9,10,12 It should be noted that although all age ranges are equally susceptible, elderly people have more risk of developing dengue with alarm signs and severe dengue with the possibility of leading to death. 4 The temporal analysis indicated that the dengue cases followed a seasonal pattern of occurrence: they began in December and January and reached greatest incidence in February and March, coinciding with the Seasonal patterns such as this, with increased case occurrence in the early months of the year, have been found in municipalities in the states of São Paulo, 9,14,15 Piauí, 16 Rio de Janeiro 17 and Santa Catarina. 18 Increased mean temperature and relative humidity of the air were, together, capable of predicting 59.4% of infestation by the vector.…”

Section: Discussionmentioning

confidence: 89%

Características da epidemia de dengue em Pinhalzinho, Santa Catarina, 2015-2016*

Andrioli¹,

Lutinski²

2020

Epidemiologia e Serviços de Saúde

View full text Add to dashboard Cite

Objective: To describe the characteristics of the dengue epidemic in Pinhalzinho, Santa Catarina, Brazil, and to investigate the effects of climate variables on Aedes aegypti mosquito infestation. Methods: This was an ecological study using data on dengue cases, hospitalizations and deaths in 2015 and 2016; in addition to climate variables and Aedes aegypti breeding grounds from 2015 to 2018. Results: In the 2015-2016 epidemic, the dengue incidence rate was 12,695.2/100,000 inhabitants. Higher incidence was registered in the female sex (13,926.4/100,000 inhabitants) and in the 50 years and over age group (17,162.0/100,000 inhabitants). Average temperature and relative humidity showed a positive relationship with increase in Aedes aegypti breeding grounds. Conclusion: Dengue incidence during the epidemic was the highest ever recorded in the country. Climate conditions must be considered when planning vector control and dengue prevention actions.

show abstract

Environmental factors can influence dengue reported cases

Cited by 21 publications

References 4 publications

Particulate matter (PM10) enhances RNA virus infection through modulation of innate immune responses

Particulate matter (PM10) enhances RNA virus infection through modulation of innate immune responses

Weather Factors Associated with Reduced Risk of Dengue Transmission in an Urbanized Tropical City

Características da epidemia de dengue em Pinhalzinho, Santa Catarina, 2015-2016*

Contact Info

Product

Resources

About